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Artículos publicados Encontrados 5 registros  La búsqueda tardó 0.02 segundos. 
1.
9 p, 1.2 MB Genetic variants of CTLA4 are associated with clinical outcome of patients with multiple myeloma / Gonzalez-Montes, Yolanda (Universitat de Girona) ; Rodriguez-Romanos, Rocío (Universitat de Girona) ; Villavicencio, Alicia (Universitat de Girona) ; Osca-Gelis, Gemma (Universitat de Girona) ; González-Bártulos, Marta (Universitat de Girona) ; Llopis, Francesca (Universitat de Girona) ; Clapes, Victòria (Hospital Universitari de Bellvitge) ; Oriol, Albert (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sureda, Anna (Hospital Universitari de Bellvitge) ; Escoda, Lourdes (Universitat Rovira i Virgili) ; Sarrà, Josep (Universitat Rovira i Virgili) ; Garzó, Ana (Universitat de Girona) ; Lloveras, Natàlia (Universitat de Girona) ; Díez, Isabel (Universitat de Girona) ; Granada, Isabel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Gallardo, David (Universitat de Girona)
Immune dysfunction in patients with multiple myeloma (MM) affects both the innate and adaptive immune system. Molecules involved in the immune checkpoint pathways are essential to determine the ability of cancer cells to escape from the immune system surveillance. [...]
2023 - 10.3389/fimmu.2023.1158105
Frontiers in immunology, Vol. 14 (april 2023)  
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2.
16 p, 3.4 MB CAR-Ts redirected against the Thomsen-Friedenreich antigen CD176 mediate specific elimination of malignant cells from leukemia and solid tumors / Dragon, Anna Christina (Hannover Medical School) ; Beermann, Luca Marie (Hannover Medical School) ; Umland, Melina (Hannover Medical School) ; Bonifacius, Agnes (Hannover Medical School) ; Malinconico, Chiara (Hannover Medical School) ; Ruhl, Louisa (Hannover Medical School) ; Kehler, Patrik (Glycotope GmbH) ; Gellert, Johanna (Glycotope GmbH) ; Weiß, Lisa (Glycotope GmbH) ; Mayer-Hain, Sarah (Glycotope GmbH) ; Zimmermann, Katharina (Hannover Medical School) ; Riese, Sebastian (Hannover Medical School) ; Thol, F. (Department of Hematology. Hannover Medical School) ; Beutel, Gernot (Hannover Medical School) ; Maecker-Kolhoff, B. (Department of Pediatric Hematology and Oncology. Hannover Medical School) ; Yamamoto, Felicitas (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Blasczyk, Rainer (Hannover Medical School) ; Schambach, Axel (Hannover Medical School) ; Hust, Michael (Department of Medical Biotechnology. Technical University of Braunschweig) ; Hudecek, Michael (Department of Internal Medicine II. University Hospital of Würzburg) ; Eiz-Vesper, Britta (Hannover Medical School) ; Universitat Autònoma de Barcelona
Introduction: Chimeric antigen receptor-engineered T cells (CAR-Ts) are investigated in various clinical trials for the treatment of cancer entities beyond hematologic malignancies. A major hurdle is the identification of a target antigen with high expression on the tumor but no expression on healthy cells, since "on-target/off-tumor" cytotoxicity is usually intolerable. [...]
2023 - 10.3389/fimmu.2023.1219165
Frontiers in immunology, Vol. 14 (2023) , p. 1219165  
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3.
22 p, 2.9 MB Advancing CART therapy for acute myeloid leukemia : recent breakthroughs and strategies for future development / Pérez-Amill, Lorena (Department of Immunology. Centre de Diagnòstic Biomèdic (CDB). Hospital Clínic de Barcelona) ; Bataller, Alex (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Delgado, Julio (Universitat de Barcelona) ; Esteve, Jordi (Universitat de Barcelona) ; Juan, Manel (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ; Klein-González, Nelia (Hospital Clínic i Provincial de Barcelona)
Chimeric antigen receptor (CAR) T therapies are being developed for acute myeloid leukemia (AML) on the basis of the results obtained for other haematological malignancies and the need of new treatments for relapsed and refractory AML. [...]
2023 - 10.3389/fimmu.2023.1260470
Frontiers in immunology, Vol. 14 (2023) , p. 1260470  
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4.
16 p, 2.1 MB Brewpitopes : a pipeline to refine B-cell epitope predictions during public health emergencies / Farriol-Duran, Roc (Barcelona Supercomputing Center) ; López-Aladid, Ruben (Pneumology Department. Hospital Clínic) ; Porta-Pardo, Eduard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Torres, Antoni (Hospital Clínic i Provincial de Barcelona) ; Fernández-Barat, Laia (Hospital Clínic i Provincial de Barcelona)
The application of B-cell epitope identification to develop therapeutic antibodies and vaccine candidates is well established. However, the validation of epitopes is time-consuming and resource-intensive. [...]
2023 - 10.3389/fimmu.2023.1278534
Frontiers in immunology, Vol. 14 (2023) , p. 1278534  
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5.
2 p, 292.1 KB Corrigendum : The paradigm of IL-23-independent production of IL-17F and IL-17A and their role in chronic inflammatory diseases(Front. Immunol., (2023), 14, (1191782), 10.3389/fimmu.2023.1191782) / Navarro-Compán, Victoria (Hospital Universitario La Paz (Madrid)) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau) ; Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ; Ramírez, Julio (Hospital Clínic i Provincial de Barcelona) ; Llamas-Velasco, Mar (Hospital Universitario de la Princesa (Madrid)) ; Fernández-Carballido, Cristina (Hospital Universitario San Juan de Alicante) ; Almodóvar, Raquel (Hospital Universitario Fundación Alcorcón) ; Pinto, José Antonio (Complejo Hospitalario Universitario de A Coruña) ; Galíndez-Aguirregoikoa, Eva (Hospital Universitario de Basurto) ; Zarco, Pedro (Hospital Universitario Fundación Alcorcón) ; Joven, Beatriz (Hospital 12 de Octubre (Madrid)) ; Gratacós, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Juanola, Xavier (Hospital Universitari de Bellvitge) ; Blanco, Ricardo (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Arias-Santiago, Salvador (Universidad de Granada) ; Sanz Sanz, Jesús (Hospital Universitario Puerta del Hierro Majadahonda) ; Queiro, Ruben (Hospital Universitario Central de Asturias) ; Cañete, Juan D. (Hospital Clínic i Provincial de Barcelona) ; Universitat Autònoma de Barcelona
In the published article, there was an error in Table 1 as published. The cell corresponding to ixekizumab in HS must be yellow rather than green, since it is not approved for that indication, nor has phase 3 clinical development been published. [...]
2023 - 10.3389/fimmu.2023.1332177
Frontiers in immunology, Vol. 14 (2023) , p. 1332177  
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