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33 p, 2.5 MB Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells / Moreno Delgado, David (Universitat de Montpellier) ; Møller, Thor C. (Universitat de Montpellier) ; Ster, Jeanne (Universitat de Montpellier) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Laboratori de Neurofarmacologia Molecular i Bioinformàtica) ; Maurel, Damien (Universitat de Montpellier) ; Rovira, Xavier (Universitat de Montpellier) ; Scholler, Pauline (Universitat de Montpellier) ; Zwier, Jurriaan M. (CisBio Bioassays, Codolet) ; Perroy, Julie (Universitat de Montpellier) ; Durroux, Thierry (Universitat de Montpellier) ; Trinquet, Eric (CisBio Bioassays, Codolet) ; Prezeau, Laurent (Universitat de Montpellier) ; Rondard, Philippe (Universitat de Montpellier) ; Pin, Jean-Philippe (Universitat de Montpellier)
Metabotropic glutamate receptors (mGluRs) are mandatory dimers playing important roles in regulating CNS function. Although assumed to form exclusive homodimers, 16 possible heterodimeric mGluRs have been proposed but their existence in native cells remains elusive. [...]
2017 - 10.7554/eLife.25233
eLife, Vol. 6 (june 2017)  
Detailed record - Creative Commons

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