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4 p, 384.4 KB Chronic Sleep Fragmentation Mimicking Sleep Apnea Does Not Worsen Left-Ventricular Function in Healthy and Heart Failure Mice / Cabrera-Aguilera, Ignacio (Departament of Human Movement Sciences, Faculty of Health Sciences, School of Kinesiology, Universidad de Talca) ; Benito, Begoña (Universitat Autònoma de Barcelona. Departament de Medicina) ; Tajes, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ; Farré, Ramon (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Gozal, David (Department of Child Health and Child Health Research Institute, The University of Missouri School of Medicine) ; Almendros, Isaac (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Farré, Núria (Hospital del Mar (Barcelona, Catalunya))
Aims: Obstructive sleep apnea (OSA) has been associated with heart failure (HF). Sleep fragmentation (SF), one of the main hallmarks of OSA, induces systemic inflammation, oxidative stress and sympathetic activation, hence potentially participating in OSA-induced cardiovascular consequences. [...]
2020 - 10.3389/fneur.2019.01364
Frontiers in neurology, Vol. 10 (january 2020)  
Detailed record - Creative Commons

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