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11 p, 4.4 MB Lung Extracellular Matrix Hydrogels Enhance Preservation of Type II Phenotype in Primary Alveolar Epithelial Cells / Marhuenda, Esther (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Villarino, Alvaro (Universitat de Barcelona) ; Narciso, Maria Leonor (Universitat de Barcelona) ; Camprubí-Rimblas, Marta (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Farré, Ramon (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Gavara, Núria (Universitat de Barcelona) ; Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Almendros, Isaac (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Otero, Jorge (Universitat de Barcelona) ; Universitat Autònoma de Barcelona
One of the main limitations of in vitro studies on lung diseases is the difficulty of maintaining the type II phenotype of alveolar epithelial cells in culture. This fact has previously been related to the translocation of the mechanosensing Yes-associated protein (YAP) to the nuclei and Rho signaling pathway. [...]
2022 - 10.3390/ijms23094888
International journal of molecular sciences, Vol. 23 (april 2022)  
Detailed record - Creative Commons

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