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Multidimensional predictors of negative symptoms in antipsychotic-naive first-episode psychosis / Toll, Alba (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Blanco Hinojo, Laura (Institut Hospital del Mar d'Investigacions Mèdiques) ; Bergé Baquero, Daniel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Duran-Jordà, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ; Canosa, Irene (Institut Hospital del Mar d'Investigacions Mèdiques) ; Legido, Teresa (Institut Hospital del Mar d'Investigacions Mèdiques) ; Mármol, Federico (Universitat de Barcelona. Departament de Fonaments Clínics) ; Pérez Solà, Víctor (Institut Hospital del Mar d'Investigacions Mèdiques) ; Fernández Egea, Emilio (University of Cambridge. Department of Psychiatry and Behavioral and Clinical Neuroscience Institute) ; Mané, Anna (Institut Hospital del Mar d'Investigacions Mèdiques)
Despite a large body of schizophrenia research, we still have no reliable predictors to guide treatment from illness onset. The present study aimed to identify baseline clinical or neurobiological factors - including peripheral brain-derived neurotrophic factor (BDNF) levels and amygdala or hippocampal relative volumes - that could predict negative symptomatology and persistent negative symptoms in first-episode psychosis after 1 year of follow-up. [...]
2022 - DOI (Digital Object Identifier)

10.1503/jpn.210138
Journal of Psychiatry & Neuroscience : JPN, Vol. 47 (january 2022) , p. E21-E31

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