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16 p, 2.6 MB |
Brain aging in major depressive disorder : results from the ENIGMA major depressive disorder working group
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Han, L.K.M. (Vrije Universiteit & GGZinGeest) ;
Dinga, Richard (Radboud University) ;
Hahn, Tim (University of Münster) ;
Ching, Christopher R. K. (University of Southern California) ;
Eyler, Lisa (University of California San Diego) ;
Aftanas, Lybomir (Novosibirsk State University) ;
Aghajani, Moji (Vrije Universiteit & GGZinGeest) ;
Aleman, André (University of Groningen) ;
Baune, Bernhard T. (The University of Melbourne) ;
Berger, Klaus (University of Münster) ;
Brak, Ivan (Novosibirsk State University) ;
Filho, Geraldo Busatto (Universidade de Sao Paulo) ;
Carballedo, Angela (North Dublin Mental Health Services) ;
Connolly, Colm G. (Florida State University) ;
Couvy-Duchesne, Baptiste (University of Queensland) ;
Cullen, Kathryn R. (University of Minnesota Medical School) ;
Dannlowski, Udo (University of Münster) ;
Davey, Christopher (The University of Melbourne) ;
Dima, Danai (King's College London) ;
Souza-Duran, Fabio Luis (Universidade de Sao Paulo) ;
Enneking, Verena (University of Münster) ;
Filimonova, Elena (Cognitive & Translational Neuroscience) ;
Frenzel, Stefan (University Medicine Greifswald) ;
Frodl, Thomas (German Center for Neurodegenerative Diseases (DZNE)) ;
Fu, Cynthia H.Y. (University of East London) ;
Godlewska, Beata (University of Oxford) ;
Gotlib, Ian H. (Stanford University) ;
Grabe, Hans J. (German Center for Neurodegenerative Diseases) ;
Groenewold, Nynke A. (University of Cape Town) ;
Grotegerd, Dominik (University of Münster) ;
Gruber, Oliver (University of Heidelberg) ;
Hall, Geoffrey B. (McMaster University (Canadà)) ;
Harrison, Ben (The University of Melbourne & Melbourne Health) ;
Hatton, Sean N. (University of California San Diego) ;
Hermesdorf, Marco (University of Münster) ;
Hickie, Ian B. (University of Sydney) ;
Ho, Tiffany C. (Standord University) ;
Hosten, Norbert (University Medicine Greifswald) ;
Jansen, Andreas (Philipps-University Marburg) ;
Kähler, Claas (University of Münster) ;
Kircher, Tilo (Philipps-University Marburg) ;
Klimes-Dougan, Bonnie (University of Minnesota) ;
Krämer, Bernd (University of Heidelberg) ;
Krug, Axel (University of Bonn) ;
Lagopoulos, Jim (University of the Sunshine Coast QLD) ;
Leenings, Ramona (University of Münster) ;
MacMaster, Frank (Addictions and Mental Health Strategic Clinical Network) ;
MacQueen, Glenda (University of Calgary) ;
McIntosh, Andrew M. (University of Edinburgh) ;
McLellan, Quinn (University of Alberta) ;
McMahon, Katie (Queensland University of Technology) ;
Medland, Sarah Elizabeth (QIMR Berghofer Medical Research Instititute) ;
Mueller, Bryon (University of Minnesota Medical School) ;
Mwangi, Benson (DepartThe University of Texas Health Science Center at Houston) ;
Osipov, Evgeny (Novosibirsk State University) ;
Portella, Maria J.. (Institut d'Investigació Biomèdica Sant Pau) ;
Pozzi, Elena (The University of Melbourne & Melbourne Health) ;
Reneman, Liesbeth (Amsterdam UMC. University Medical Center) ;
Repple, Jonathan (University of Münster) ;
Gomes Penteado Rosa, Pedro (Universidade de Sao Paulo) ;
Sacchet, Matthew D. (Harvard Medical School) ;
Sämann, Philipp G. (Max Planck Institute of Psychiatry) ;
Schnell, Knut (Asklepios Fachklinikum Göttingen) ;
Schrantee, Anouk (Amsterdam UMC. University Medical Center) ;
Simulionyte, Egle (McMaster University (Canadà)) ;
Soares, Jair C. (The University of Texas Health Science Center at Houston) ;
Sommer, Jens (University of Minnesota) ;
Stein, Dan J. (University of Cape Town) ;
Steinsträter, Olaf (University Medicine Greifswald) ;
Strike, Lachlan (University of Queensland) ;
Thomopoulos, Sophia I. (University of Southern California) ;
van Tol, Marie-José (University of Groningen) ;
Veer, Ilya M. (DiCharité-Universitätsmedizin Berlin) ;
Vermeiren, Robert R. J. M. (Leiden University) ;
Walter, Henrik (Charité - Universitätsmedizin Berlin) ;
van der Wee, Nic J. A. (Leiden University Medical Center) ;
van der Werff, Steven J. A. (Leiden University Medical Center) ;
Whalley, Heather (University of Edinburgh) ;
Winter, Nils Ralf (University of Münster) ;
Wittfeld, Katharina (German Center of Neurodegenerative Diseases (DZNE) Site Rostock/Greifswald) ;
Wright, Margaret J (University of Queensland) ;
Wu, Mon-Ju (The University of Texas Health Science Center at Houston) ;
Völzke, Henry (University Medicine Greifswald) ;
Yang, Tony T. (UCSF School of Medicine) ;
Zannias, Vasileios (University of Edinburgh) ;
de Zubicaray, Greig (Queensland University of Technology) ;
Zunta-Soares, Giovana B. (The University of Texas Health Science Center at Houston) ;
Abé, Christoph (Karolinska Institutet (Estocolm, Suècia)) ;
Alda, Martin (Dalhousie University) ;
Andreassen, Ole A. (Oslo University Hospital (Oslo, Noruega)) ;
Bøen, Erlend (Oslo University Hospital (Oslo, Noruega)) ;
Bonnin, Caterina del Mar (Hospital Clínic i Provincial de Barcelona) ;
Canales-Rodriguez, Erick Jorge (FIDMAG Germanes Hospitalàries Research Foundation) ;
Cannon, Dara (National University of Ireland Galway) ;
Caseras, Xavier (Cardiff University) ;
Chaim-Avancini, Tiffany M. (Universidade de Sao Paulo) ;
Elvsåshagen, Torbjørn (Oslo University Hospital (Oslo, Noruega)) ;
Favre, Pauline (Hôpitaux Universitaires Mondor) ;
Foley, Sonya (Cardiff University) ;
Fullerton, Janice M. (University of New South Wales) ;
Goikolea Alberdi, Jose Manuel (Hospital Clínic i Provincial de Barcelona) ;
Haarman, Bartholomeus C. M. (University of Groningen) ;
Hajek, Tomas (Dalhousie University) ;
Henry, Chantal (Université de Paris) ;
Houenou, Josselin (Hôpitaux Universitaires Mondor) ;
Howells, Fleur M. (University of Cape Town) ;
Ingvar, Martin (Karolinska Institutet (Estocolm, Suècia)) ;
Kuplicki, Rayus (Laureate Institute for Brain Research) ;
Lafer, B. (University of Sao Paulo (FMUSP)) ;
Landén, Mikael (Karolinska Institutet (Estocolm, Suècia)) ;
Machado-Vieira, Rodrigo (University of Sao Paulo (FMUSP)) ;
Malt, Ulrik (Oslo University Hospital (Oslo, Noruega)) ;
McDonald, Colm (National University of Ireland Galway) ;
Mitchell, Philip B. (Prince of Wales Hospital (Australia)) ;
Nabulsi, Leila (National University of Ireland Galway) ;
Otaduy, Maria C. G. (Universidade de Sao Paulo) ;
Overs, Bronwyn J. (Neuroscience Research Australia) ;
Polosan, Mircea (Grenoble Institut des Neurosciences) ;
Pomarol-Clotet, Edith (FIDMAG Germanes Hospitalàries Research Foundation) ;
Radua, Joaquim (Hospital Clínic i Provincial de Barcelona) ;
Rive, Maria M. (Amsterdam UMC. University Medical Center) ;
Roberts, Gloria (Prince of Wales Hospital (Australia)) ;
Ruhe, Henricus G. (Radboud University Medical Center) ;
Salvador, Raymond (FIDMAG Germanes Hospitalàries Research Foundation) ;
Sarró, Salvador (FIDMAG Germanes Hospitalàries Research Foundation) ;
Satterthwaite, Theodore D (University of Pennsylvannia Perelman School of Medicine) ;
Savitz, Jonathan (The University of Tulsa) ;
Schene, Aart H. (Radboud University Medical Center) ;
Schofield, Peter R. (University of New South Wales) ;
Serpa, Mauricio (Universidade de Sao Paulo) ;
Sim, Kang (National University of Singapore) ;
Soeiro-de-Souza, M.G. (University of Sao Paulo (FMUSP)) ;
Sutherland, Ashley N. (University of California San Diego) ;
Temmingh, Henk S. (Valkenberg Psychiatric Hospital) ;
Timmons, Garrett M. (University of California San Diego) ;
Uhlmann, Anne (University of Cape Town) ;
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona) ;
Wolf, Daniel H. (University of Pennsylvannia Perelman School of Medicine) ;
Zanetti, Marcus Vinicius (Hospital Sírio-Libanês) ;
Jahanshad, Neda (University of Southern California) ;
Thompson, Paul M. (University of Southern California) ;
Veltman, Dick J. (Vrije Universiteit & GGZinGeest) ;
Penninx, Brenda WJH. (Vrije Universiteit & GGZinGeest) ;
Marquand, Andre F. (Radboud University Medical Centre) ;
Cole, James Howard (University College London) ;
Schmaal, Lianne (The University of Melbourne) ;
Universitat Autònoma de Barcelona
Major depressive disorder (MDD) is associated with an increased risk of brain atrophy, aging-related diseases, and mortality. We examined potential advanced brain aging in adult MDD patients, and whether this process is associated with clinical characteristics in a large multicenter international dataset. [...]
2021 -  10.1038/s41380-020-0754-0
Molecular psychiatry, Vol. 26 Núm. 9 (september 2021) , p. 5124-5139
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33 p, 892.7 KB |
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
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Mullins, Niamh ;
Kang, JooEun ;
Campos, Adrian I. ;
Coleman, Jonathan R.I. ;
Edwards, Alexis C. ;
Galfalvy, Hanga ;
Levey, Daniel F. ;
Lori, Adriana ;
Shabalin, Andrey ;
Starnawska, Anna ;
Su, Mei-Hsin ;
Watson, Hunna J. ;
Adams, Mark ;
Awasthi, Swapnil ;
Gandal, Michael ;
Hafferty, Jonathan D. ;
Hishimoto, Akitoyo ;
Kim, Minsoo ;
Okazaki, Satoshi ;
Otsuka, Ikuo ;
Ripke, Stephan ;
Ware, Erin B. ;
Bergen, Andrew W. ;
Berrettini, Wade H. ;
Bohus, Martin ;
Brandt, Harry ;
Chang, Xiao ;
Chen, Wei J. ;
Chen, Hsi-Chung ;
Crawford, Steven ;
Crow, Scott ;
DiBlasi, Emily ;
Duriez, Philibert ;
Fernández-Aranda, Fernando (Hospital Universitari de Bellvitge) ;
Fichter, Manfred M. ;
Gallinger, Steven ;
Glatt, Stephen J. ;
Gorwood, Philip ;
Guo, Yiran ;
Hakonarson, Hakon ;
Halmi, Katherine A. ;
Hwu, Hai-Gwo ;
Jain, Sonia ;
Jamain, Stéphane ;
Jiménez-Murcia, Susana (Hospital Universitari de Bellvitge) ;
Johnson, Craig ;
Kaplan, Allan S. ;
Kaye, Walter H. ;
Keel, Pamela K. ;
Kennedy, James L. ;
Klump, Kelly L. ;
Li, Dong (Children's Hospital of Philadelphia (Pennsilvània)) ;
Liao, Shih-Cheng ;
Lieb, Klaus ;
Lilenfeld, Lisa ;
Liu, Chih-Min ;
Magistretti, Pierre J. ;
Marshall, Christian R. ;
Mitchell, James E. ;
Monson, Eric T. ;
Myers, Richard M. ;
Pinto, Dalila ;
Powers, Abigail ;
Ramoz, Nicolas ;
Roepke, Stefan ;
Rozanov, Vsevolod ;
Scherer, Stephen W. ;
Schmahl, Christian ;
Sokolowski, Marcus ;
Strober, Michael ;
Thornton, Laura M. ;
Treasure, Janet ;
Tsuang, Ming T. ;
Witt, Stephanie H. ;
Woodside, D. Blake ;
Yilmaz, Zeynep ;
Zillich, Lea ;
Adolfsson, Rolf ;
Agartz, Ingrid ;
Air, Tracy M. ;
Alda, Martin ;
Alfredsson, Lars ;
Andreassen, Ole A. ;
Anjorin, Adebayo ;
Appadurai, Vivek ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron) ;
Van der Auwera, Sandra ;
Azevedo, M. Helena ;
Bass, Nicholas ;
Bau, Claiton Henrique Dotto ;
Baune, Bernhard T. ;
Bellivier, Frank ;
Berger, Klaus ;
Biernacka, Joanna M. ;
Bigdeli, Tim B. ;
Binder, Elisabeth B. ;
Boehnke, Michael ;
Boks, Marco P. ;
Bosch, Rosa (Hospital Universitari Vall d'Hebron) ;
Braff, David L. ;
Bryant, Richard ;
Budde, Monika ;
Byrne, Enda M. ;
Cahn, Wiepke ;
Casas Brugué, Miquel (Hospital Universitari Vall d'Hebron) ;
Castelao, Enrique ;
Cervilla, Jorge A. ;
Chaumette, Boris ;
Cichon, Sven ;
Corvin, Aiden ;
Craddock, Nicholas ;
Craig, David ;
Degenhardt, Franziska ;
Djurovic, Srdjan ;
Edenberg, Howard J. ;
Fanous, Ayman H. ;
Foo, Jerome C. ;
Forstner, Andreas J. ;
Frye, Mark ;
Fullerton, Janice M. ;
Gatt, Justine M. ;
Gejman, Pablo V. ;
Giegling, Ina ;
Grabe, Hans J. ;
Green, Melissa J. ;
Grevet, Eugenio H. ;
Grigoroiu-Serbanescu, Maria ;
Gutierrez, Blanca ;
Guzman-Parra, Jose ;
Hamilton, Steven P. ;
Hamshere, Marian L. ;
Hartmann, Annette ;
Hauser, Joanna ;
Heilmann-Heimbach, Stefanie ;
Hoffmann, Per ;
Ising, Marcus ;
Jones, Ian ;
Jones, Lisa A. ;
Jonsson, Lina ;
Kahn, René S. ;
Kelsoe, John R. ;
Kendler, Kenneth S. ;
Kloiber, Stefan ;
Koenen, Karestan C. ;
Kogevinas, M ;
Konte, Bettina ;
Krebs, Marie-Odile ;
Landén, Mikael ;
Lawrence, Jacob ;
Leboyer, Marion ;
Lee, Phil H. ;
Levinson, Douglas F. ;
Liao, Calwing ;
Lissowska, Jolanta ;
Lucae, Susanne ;
Mayoral-Cleries, Fermín ;
McElroy, Susan L. ;
McGrath, Patrick ;
McGuffin, Peter ;
McQuillin, Andrew ;
Medland, Sarah E. ;
Mehta, Divya ;
Melle, Ingrid ;
Milaneschi, Yuri ;
Mitchell, Philip B. ;
Molina, Esther ;
Morken, Gunnar ;
Bo Mortensen, Preben ;
Müller-Myhsok, Bertram ;
Nievergelt, Caroline ;
Nimgaonkar, Vishwajit ;
Nöthen, Markus M. ;
O'Donovan, Michael C. (Cardiff University) ;
Ophoff, Roel A. ;
Owen, Michael J. ;
Pato, Carlos ;
Pato, Michele T. ;
Penninx, Brenda WJH ;
Pimm, Jonathan ;
Pistis, Giorgio ;
Potash, James B. ;
Power, Robert A. ;
Preisig, Martin ;
Quested, Digby ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Reif, Andreas ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron) ;
Richarte, Vanesa (Hospital Universitari Vall d'Hebron) ;
Rietschel, Marcella ;
Rivera, Margarita ;
Roberts, Andrea ;
Roberts, Gloria ;
Rouleau, Guy A. ;
Rovaris, Diego L. ;
Rujescu, Dan ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron) ;
Sanders, Alan R. ;
Schofield, Peter R. ;
Schulze, Thomas G. ;
Scott, Laura J. ;
Serretti, Alessandro ;
Shi, Jianxin ;
Shyn, Stanley I. ;
Sirignano, Lea ;
Sklar, Pamela ;
Smeland, Olav B. ;
Smoller, Jordan W. ;
Sonuga-Barke, Edmund J.S. ;
Spalletta, Gianfranco ;
Strauss, John S. ;
Świątkowska, Beata ;
Trzaskowski, Maciej ;
Turecki, Gustavo ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron) ;
Vincent, John B. ;
Völzke, Henry ;
Walters, James T.R. ;
Weickert, Cynthia Shannon ;
Weickert, Thomas W. ;
Weissman, Myrna M. ;
Williams, Leanne M. ;
Wray, Naomi R. ;
Zai, Clement C. ;
Ashley-Koch, Allison E. ;
Beckham, Jean C. ;
Hauser, Elizabeth R. ;
Hauser, Michael A. ;
Kimbrel, Nathan A. ;
Lindquist, Jennifer H. ;
McMahon, Benjamin ;
Oslin, David W. ;
Qin, Xuejun ;
Agerbo, Esben ;
Børglum, Anders D. ;
Breen, Gerome ;
Erlangsen, Annette ;
Esko, Tõnu ;
Gelernter, Joel ;
Hougaard, David M. ;
Kessler, Ronald C. ;
Kranzler, Henry R. ;
Li, Qingqin S. ;
Martin, Nicholas G. ;
McIntosh, Andrew M. ;
Mors, Ole ;
Nordentoft, Merete ;
Olsen, Catherine M. ;
Porteous, David ;
Ursano, Robert J. ;
Wasserman, Danuta ;
Werge, Thomas ;
Whiteman, David C. ;
Bulik, Cynthia M. ;
Coon, Hilary ;
Demontis, Ditte ;
Docherty, Anna R. ;
Kuo, Po-Hsiu ;
Lewis, Cathryn M. ;
Mann, J. John ;
Rentería, Miguel E. ;
Smith, Daniel J. ;
Stahl, Eli A. ;
Stein, Murray B. ;
Streit, Fabian ;
Willour, Virginia ;
Ruderfer, Douglas M. ;
Universitat Autònoma de Barcelona
Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. [...]
2021 - 10.1016/j.biopsych.2021.05.029
Biological psychiatry, Vol. 91 (september 2021) , p. 313-327
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