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Genome-wide association study of circulating interleukin 6 levels identifies novel loci
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Ahluwalia, Tarunveer Singh (University of Copenhagen) ;
Prins, Bram Peter (University of Groningen) ;
Abdollahi, Mohammadreza (University of Groningen) ;
Armstrong, Nicola (Murdoch University) ;
Aslibekyan, Stella (University of Alabama at Birmingham School of Public Health) ;
Bain, Lisa J (Qimr Berghofer Medical Research Institute) ;
Jefferis, Barbara (University College London) ;
Baumert, Jens (Helmholtz Zentrum München-German Research Center for Environmental Health) ;
Beekman, Marian (Leiden University Medical Center) ;
Ben-Shlomo, Yoav (University of Bristol) ;
Bis, Joshua C (University of Washington) ;
Mitchell, Braxton D. (University of Maryland School of Medicine) ;
de Geus, Eco J. C (Amsterdam UMC. University Medical Center) ;
Delgado, Graciela E. (University of Heidelberg) ;
Marek, Diana (Sib Swiss Institute of Bioinformatics) ;
Eriksson, Joel (University of Gothenburg) ;
Kajantie, Eero (Helsinki University Central Hospital and University of Helsinki) ;
Kanoni, Stavroula (Queen Mary University of London) ;
Kemp, John P. (University of Bristol) ;
Lu, Chen (Boston University School of Public Health) ;
Marioni, Riccardo E. (University of Edinburgh) ;
McLachlan, Stela (University of Edinburgh) ;
Milaneschi, Yuri (Amsterdam Umc. Vrije Universiteit) ;
Nolte, Ilja M. (University of Groningen) ;
Petrelis, Alexandros M. (Université de Lorraine) ;
Porcu, Eleonora (Consiglio Nazionale Delle Ricerche) ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Naderi, Elnaz (University of Groningen) ;
Seppälä, Ilkka (Tampere University) ;
Shah, Tina (University College London) ;
Singhal, Gaurav (University of Adelaide) ;
Standl, Marie (Helmholtz Zentrum München-German Research Center for Environmental Health) ;
Teumer, Alexander (University Medicine Greifswald) ;
Thalamuthu, Anbupalam (University of New South Wales) ;
Thiering, Elisabeth (Ludwig-Maximilians-University of Munich. Dr. von Hauner Children's Hospital) ;
Trompet, Stella (Leiden University Medical Center) ;
Ballantyne, Christie M. (Baylor College of Medicine) ;
Benjamin, Emelia J. (Boston University School of Medicine) ;
Casas, Juan P. (Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC). Va Boston Healthcare System) ;
Toben, Catherine (University of Adelaide) ;
Dedoussis, George (Harokopio University) ;
Deelen, Joris (Max Planck Institute for Biology of Ageing) ;
Durda, Peter (Larner College of Medicine. University of Vermont) ;
Engmann, Jorgen (University College London) ;
Feitosa, Mary (Washington University School of Medicine) ;
Grallert, Harald (German Center for Diabetes Research (DZD)) ;
Hammarstedt, Ann (Sahlgrenska Academy at the University of Gothenburg) ;
Harris, Sarah E (University of Edinburgh) ;
Homuth, Georg (University Medicine Greifswald) ;
Hottenga, Jouke Jan (Amsterdam UMC. University Medical Center) ;
Jalkanen, Sirpa (University of Turku) ;
Jamshidi, Yalda (St George's University of London) ;
Jawahar, Magdalene C. (University of Adelaide) ;
Jess, Tine (Statens Serum Institute) ;
Kivimaki, Mika (University College London) ;
Kleber, Marcus E. (University of Heidelberg) ;
Lahti, Jari (University of Helsinki) ;
Liu, Yongmei (Wake Forest School of Medicine) ;
Marques-Vidal, Pedro (University of Lausanne) ;
Mellström, Dan (Sahlgrenska Academy at the University of Gothenburg. Centre for Bone and Arthritis Research) ;
Mooijaart, Simon P. (Leiden University Medical Center) ;
Müller-Nurasyid, Martina (Johhanes Gutenberg University) ;
Penninx, Brenda WJH (Amsterdam Umc. Vrije Universiteit) ;
Revez, Joana A. (Qimr Berghofer Medical Research Institute) ;
Rossing, Peter (University of Copenhagen) ;
Raïkkönen, Katri (University of Helsinki) ;
Sattar, Naveed (Bhf Glasgow Cardiovascular Research Centre) ;
Scharnagl, Hubert (Medical University of Graz) ;
Sennblad, Bengt (Uppsala University) ;
Silveira, Angela (Karolinska Institutet (Estocolm, Suècia)) ;
Pourcain, Beate St (Radboud University) ;
Timpson, Nicholas J. (University of Bristol) ;
Trollor, Julian (University of New South Wales) ;
Van Dongen, Jenny (Amsterdam UMC. University Medical Center) ;
Van Heemst, Diana (Baylor College of Medicine) ;
Visvikis-Siest, Sophie (Université de Lorraine. Inserm. IGE-PCV) ;
Vollenweider, Peter (University of Lausanne) ;
Völker, Uwe (University of Turku) ;
Waldenberger, Melanie (Helmholtz Zentrum München-German Research Center for Environmental Health) ;
Willemsen, Gonneke (Amsterdam UMC. University Medical Center) ;
Zabaneh, Delilah (University College London Genetics Institute) ;
Morris, Richard W. (Bristol Medical School. University of Bristol) ;
Arnett, Donna K. (University of Kentucky) ;
Baune, Bernhard T. (University of Melbourne) ;
Boomsma, Dorret I. (Amsterdam UMC. University Medical Center) ;
Chang, Yen-Pei C. (University of Maryland School of Medicine) ;
Deary, Ian J. (University of Edinburgh) ;
Deloukas, Panos (Queen Mary University of London) ;
Eriksson, Johan G. (University of Helsinki) ;
Evans, David M. (University of Bristol) ;
Ferreira, Manuel A. (Qimr Berghofer Medical Research Institute) ;
Gaunt, Tom (University of Bristol) ;
Gudnason, Vilmundur (University of Iceland) ;
Hamsten, Anders (Karolinska Institutet (Estocolm, Suècia)) ;
Heinrich, Joachim (University of Melbourne) ;
Hingorani, Aroon (University College London) ;
Humphries, Steve E. (University College London) ;
Jukema, J. Wouter (Durrer Center for Cardiogenetic Research) ;
Koenig, Wolfgang (University of Ulm) ;
Kumari, Meena (University of Essex) ;
Kutalik, Zoltan (University of Lausanne) ;
Lawlor, Deborah A. (University of Bristol) ;
Lehtimäki, Terho (Tampere University) ;
März, Winfried (Synlab Academy. Synalb Holding Deutschland GmbH) ;
Mather, Karen A (Neuroscience Research Australia) ;
Naitza, Silvia. (Consiglio Nazionale Delle Ricerche) ;
Nauck, Matthias (Dzhk (German Center for Cardiovascular Research). Partner Site Greifswald) ;
Ohlsson, Claes (University of Gothenburg) ;
Price, Jackie F. (University of Edinburgh) ;
Raitakari, Olli (Turku University Hospital (Finlàndia)) ;
Rice, Ken (University of Washington) ;
Sachdev, Perminder S. (Prince of Wales Hospital (Australia)) ;
Slagboom, Pieternella Eline (Max Planck Institute for Biology of Ageing) ;
Sørensen, Thorkild I.A. (University of Copenhagen. Department of Public Health. Section on Epidemiology) ;
Spector, Tim (King's College London. Department of Twin Research and Genetic Epidemiology) ;
Stacey, David (University of Cambridge) ;
Stathopoulou, Maria G. (Université de Lorraine. Inserm. IGE-PCV) ;
Tanaka, Toshiko (National Institute on Aging (Estats Units d'Amèrica)) ;
Wannamethee, Sasiwarang Goya (University College London) ;
Whincup, Peter (University of London) ;
Rotter, Jerome I. (The Lundquist Institute at Harbor-UCLA Medical Center) ;
Dehghan, Abbas (Erasmus Mc) ;
Boerwinkle, Eric (Baylor College of Medicine) ;
Psaty, Bruce M. (University of Washington) ;
Snieder, Harold (University Medical Center Groningen) ;
Alizadeh, Behrooz Ziad (University Medical Center Groningen)
Interleukin 6 (IL-6) is a multifunctional cytokine with both pro-A nd anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex disease pathogenesis. [...]
2021 -  10.1093/hmg/ddab023
Human Molecular Genetics, Vol. 30 Núm. 5 (january 2021) , p. 393-409
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