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Articles, 4 registres trobats
Articles 4 registres trobats  
1.
10 p, 531.5 KB Expert consensus on the use of systemic glucocorticoids for managing eosinophil-related diseases / Del Pozo, Victoria (Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD)) ; Bobolea, Irina (Hospital Clínic i Provincial de Barcelona) ; Rial, Manuel J. (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES)) ; Espigol-Frigolé, Georgina (Hospital Clínic i Provincial de Barcelona) ; Solans, Roser (Hospital Universitari Vall d'Hebron) ; Hernández Rivas, Jesús María (Hospital Universitario de Salamanca) ; Mora, Elvira (La Fe University and Polytechnic Hospital) ; Crespo Lessmann, Astrid (Hospital de la Santa Creu i Sant Pau) ; Izquierdo Alonso, José Luis (Guadalajara University Hospital) ; Domínguez Sosa, María Sandra (University Hospital of Gran Canaria Dr. Negrín) ; Maza-Solano, Juan (University Hospital, Sevilla) ; Atienza-Mateo, Belén (Instituto de Investigación Marqués de Valdecilla (IDIVAL)) ; Bañas-Conejero, David (Specialty Care Medical Department, GSK) ; Moure, Abraham L. (Specialty Care Medical Department, GSK) ; Rua Figueroa, Íñigo (University Hospital of Gran Canaria Dr. Negrín) ; Universitat Autònoma de Barcelona. Departament de Medicina
Eosinophil-related diseases represent a group of pathologic conditions with highly heterogeneous clinical presentation and symptoms ranging from mild to critical. Both systemic and localized forms of disease are typically treated with glucocorticoids. [...]
2024 - 10.3389/fimmu.2023.1310211
Frontiers in immunology, Vol. 14 (january 2024)  
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2.
12 p, 3.1 MB Remission outcomes in severe eosinophilic asthma with mepolizumab therapy : Analysis of the REDES study / Pavord, Ian (University of Oxford) ; Gardiner, Frances (GSK House) ; Heaney, Liam G. (Queen's University Belfast) ; Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Price, Robert G. (Biostatistics, GSK) ; Pullan, Alison (Plus-Project Partnership Ltd) ; Oppenheimer, John (UMDNJ-Rutgers New Jersey Medical School) ; Brusselle, Guy (Universitair Ziekenhuis Gent) ; Nagase, Hiroyuki (Teikyo University School of Medicine) ; Chupp, Geoffrey (Yale Center for Asthma and Airways Disease (YCAAD)) ; Pizzichini, Emilio (Federal University of Santa Catarina) ; Bañas-Conejero, David (GSK) ; Howarth, Peter (GSK House) ; Universitat Autònoma de Barcelona
Clinical remission as a multicomponent treatment goal in severe asthma is being explored in clinical practice. This post hoc analysis used data from the REDES study to assess the proportion of patients with severe eosinophilic asthma achieving our multicomponent definitions of clinical remission after 1 year of mepolizumab treatment. [...]
2023 - 10.3389/fimmu.2023.1150162
Frontiers in immunology, Vol. 14 (april 2023)  
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3.
6 p, 1.0 MB Potential Impact of Mepolizumab in Stepping Down Anti-Osteporotic Treatment in Corticosteroid-Dependent Asthma / Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Sogo, Ana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Casado, Enrique (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Moragón, Eva Martínez (Hospital Universitari Doctor Peset (València)) ; Blanco-Aparicio, Marina (Complejo Hospitalario Universitario de A Coruña) ; Carrillo Díaz, Teresa (Hospital Universitario de Gran Canaria Dr. Negrín) ; Bañas-Conejero, David (GSK (Espanya)) ; Serrato Sánchez, Gloria Maria Guadalupe (GSK (Espanya)) ; Universitat Autònoma de Barcelona
Oral corticosteroids (OCS) are commonly used for the acute management of severe asthma exacerbations or as maintenance therapy; however, chronic use is associated with significant toxicities, e. g. , osteoporosis. [...]
2023 - 10.3389/fphar.2023.1183156
Frontiers in Pharmacology, Vol. 14 (2023) , p. 1183156  
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4.
12 p, 1.1 MB REal worlD Effectiveness and Safety of Mepolizumab in a Multicentric Spanish Cohort of Asthma Patients Stratified by Eosinophils : The REDES Study / Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Carrillo Díaz, Teresa (Universidad de Las Palmas de Gran Canaria) ; Blanco Aparicio, Marina (H. Universitario A Coruña) ; Martínez Moragón, Eva (H. Universitario Doctor Peset, Valencia) ; Bañas-Conejero, David (GlaxoSmithKline. Specialty Care Medical Department) ; Sánchez Herrero, M. Guadalupe (GlaxoSmithKline. Specialty Care Medical Department) ; Universitat Autònoma de Barcelona. Departament de Medicina
The efficacy of mepolizumab is well documented in severe eosinophilic asthma (SEA), although the stringent selection criteria adopted by SEA clinical trials limits the generalizability of results. Our study evaluated the effectiveness and safety of mepolizumab in patients with SEA in Spain. [...]
2021 - 10.1007/s40265-021-01597-9
Drugs, Vol. 81 (september 2021) , p. 1763-1774
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