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Artículos Encontrados 2 registros  
1.
35 p, 10.2 MB Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders / Segal, Ashlea (Monash University) ; Parkes, Linden (Rutgers University. Department of Psychiatry) ; Aquino, Kevin (BrainKey (Estats Units d'Amèrica)) ; Kia, Seyed Mostafa (Tilburg University. Department of Cognitive Science and Artificial Intelligence) ; Wolfers, Thomas (University of Tübingen. Department of Psychiatry and Psychotherapy) ; Franke, Barbara (Radboud University Medical Center. Department of Human Genetics) ; Hoogman, Martine (Radboud University Medical Center. Department of Human Genetics) ; Beckmann, Christian F. (University of Oxford. Nuffield Department of Clinical Neurosciences) ; Westlye, Lars T. (University of Oslo) ; Andreassen, Ole A. (University of Oslo) ; Zalesky, Andrew (The University of Melbourne. Department of Biomedical Engineering) ; Harrison, Ben J. (The University of Melbourne. Department of Psychiatry) ; Davey, Christopher (University of Melbourne. Department of Psychiatry) ; Soriano-Mas, Carles (Universitat de Barcelona. Departament de Psicologia Social i Psicologia Quantitativa) ; Cardoner, N. (Narcís) (Universitat Autònoma de Barcelona) ; Tiego, Jeggan (Monash University) ; Yücel, Murat (QIMR Berghofer Medical Research Institute (Austràlia)) ; Braganza, Leah (Monash University) ; Suo, Chao (Monash eResearch Centre (Austràlia)) ; Berk, Michael (Florey Institute for Neuroscience and Mental Health) ; Cotton, Sue (University of Melbourne. Centre for Youth Mental Health) ; Bellgrove, Mark A. (Monash University) ; Marquand, Andre F. (King's College London. Department of Neuroimaging) ; Fornito, Alex (Monash University)
The substantial individual heterogeneity that characterizes people with mental illness is often ignored by classical case-control research, which relies on group mean comparisons. Here we present a comprehensive, multiscale characterization of the heterogeneity of gray matter volume (GMV) differences in 1,294 cases diagnosed with one of six conditions (attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, depression, obsessive-compulsive disorder and schizophrenia) and 1,465 matched controls. [...]
2023 - 10.1038/s41593-023-01404-6
Nature Neuroscience, Vol. 26 (august 2023) , p. 1613-1629  
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2.
11 p, 1.3 MB Specific patterns of brain alterations underlie distinct clinical profiles in Huntington's disease / Garcia-Gorro, Clara (Departament de Cognició, Desenvolupament i Psicologia de l'Educació) ; Llera, A. (Radboud University Medical Centre. Centre for Cognitive Neuroimaging) ; Martinez-Horta, Saul (Institut d'Investigació Biomèdica Sant Pau) ; Pérez-Pérez, Jesús (Institut d'Investigació Biomèdica Sant Pau) ; Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ; Rodriguez-Dechicha, N. (Hospital Duran i Reynals (Barcelona)) ; Vaquer, Irene (Hospital Duran i Reynals (Barcelona)) ; Subira, Susana (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ; Calopa, Matilde (Hospital Universitari de Bellvitge) ; Muñoz García, José Esteban (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut) ; Santacruz, Pilar (Hospital Clínic i Provincial de Barcelona) ; Ruiz-Idiago, J. (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Mareca, Celia (Hospital Mare de Deu de la Mercè) ; Beckmann, Christian F (Donders Institute for Brain. Cognition and Behaviour. Department of Cognitive Neuroscience. Radboud University Medical Center) ; de Diego-Balaguer, Ruth (Institució Catalana de Recerca i Estudis Avançats) ; Camara, Estela (Institut d'Investigació Biomèdica de Bellvitge)
Huntington's disease (HD) is a genetic neurodegenerative disease which involves a triad of motor, cognitive and psychiatric disturbances. However, there is great variability in the prominence of each type of symptom across individuals. [...]
2019 - 10.1016/j.nicl.2019.101900
NeuroImage, Vol. 23 (2019) , p. 101900  
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