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10 p, 855.6 KB Cerebrospinal fluid levels of the neurotrophic factor neuroleukin are increased in early Alzheimer's disease, but not in cerebral amyloid angiopathy / De Kort, A.M. (Department of Neurology. Radboud University Medical Center. Donders Institute for Brain. Cognition and Behaviour. Radboud Alzheimer Centre) ; Kuiperij, H.B. (Department of Neurology. Radboud University Medical Center. Donders Institute for Brain. Cognition and Behaviour. Radboud Alzheimer Centre) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Kersten, I. (Department of Neurology. Radboud University Medical Center. Donders Institute for Brain. Cognition and Behaviour. Radboud Alzheimer Centre) ; Versleijen, A.A.M. (Department of Laboratory Medicine. Radboud University Medical Center) ; Greenberg, S.M. (Massachusetts General Hospital (Boston)) ; Stoops, E. (ADx NeuroSciences) ; Schreuder, F.H.B.M. (Department of Neurology. Radboud University Medical Center. Donders Institute for Brain. Cognition and Behaviour. Radboud Alzheimer Centre) ; Klijn, C.J.M. (Department of Neurology. Radboud University Medical Center. Donders Institute for Brain. Cognition and Behaviour. Radboud Alzheimer Centre) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Claassen, Jurgen A. H. R (Radboud University Medical Centre. Department of Geriatrics) ; Verbeek, M.M. (Department of Laboratory Medicine. Radboud University Medical Center) ; Universitat Autònoma de Barcelona
Background: Neuroleukin (NLK) is a protein with neurotrophic properties and is present in a proportion of senile plaques and amyloid laden vessels. It has been suggested that NLK is part of a neuroprotective response to amyloid β-induced cell death. [...]
2021 - 10.1186/s13195-021-00899-0
Alzheimer's research & therapy, Vol. 13 Núm. 1 (december 2021) , p. 160  
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