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Articles 2 records found  
1.
1.2 MB Molecular landscape and prognostic impact of FLT3 -ITD insertion site in acute myeloid leukemia : RATIFY study results / Rücker, Frank G. (University Hospital of Ulm (Alemanya)) ; Du, Ling (Novartis Pharmaceuticals, Cambridge) ; Luck, Tamara J. (Charité University, Berlin) ; Benner, Axel (German Cancer Research Center, Heidelberg) ; Krzykalla, Julia (German Cancer Research Center, Heidelberg) ; Gathmann, Insa (Novartis Pharmaceuticals, Basel) ; Voso, Maria Teresa (Università di Roma "Tor Vergata", Rome) ; Amadori, Sergio (Università di Roma "Tor Vergata", Rome) ; Prior, Thomas W. (The Ohio State University Comprehensive Cancer Center, Columbus) ; Brandwein, Joseph M. (University of Alberta, Edmonton) ; Appelbaum, Frederick (Fred Hutchinson Cancer Research Center, Seattle) ; Medeiros, Bruno (Stanford University) ; Tallman, Martin S. (Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York) ; Savoie, Lynn (University of Calgary, Calgary) ; Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ; Pallaud, Celine (Novartis Pharmaceuticals, Basel) ; Sanz, Miguel A.. (Hospital Universitari i Politècnic La Fe (València)) ; Jansen, Joop H. (Radboud University Medical Center, Nijmegen) ; Niederwieser, Dietger (Hematology and Oncology, University of Leipzig, Leipzig) ; Fischer, Thomas (Otto-von-Guericke University Magdeburg, Magdeburg) ; Ehninger, Gerhard (Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden) ; Heuser, Michael (Hannover Medical School, Hannover) ; Ganser, Arnold (Oncology and Stem Cell Transplantation, Hannover) ; Bullinger, Lars (Charité University, Berlin) ; Larson, Richard A. (University of Chicago, Chicago) ; Bloomfield, Clara D. (The Ohio State University Comprehensive Cancer Center, Columbus) ; Stone, Richard M. (Dana-Farber/Partners CancerCare, Boston) ; Döhner, Hartmut (University Hospital of Ulm (Alemanya)) ; Thiede, Christian (Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden) ; Döhner, Konstanze (University Hospital of Ulm (Alemanya)) ; Universitat Autònoma de Barcelona
In acute myeloid leukemia (AML) internal tandem duplications of the FLT3 gene (FLT3- ITD) are associated with poor prognosis. Retrospectively, we investigated the prognostic and predictive impact of FLT3 -ITD insertion site (IS) in 452 patients randomized within the RATIFY trial, which evaluated midostaurin additionally to intensive chemotherapy. [...]
2021 - 10.1038/s41375-021-01323-0
Leukemia, Vol. 36 (july 2021) , p. 90-99  
Detailed record - Creative Commons
2.
8 p, 732.8 KB Optimized EBMT transplant-specific risk score in myelodysplastic syndromes after allogeneic stem-cell transplantation / Gagelmann, N. (University Medical Center Hamburg-Eppendorf) ; Eikema, D. J. (EBMT Statistics) ; Stelljes, M. (University of Münster) ; Beelen, D. (University Hospital Essen (Alemanya)) ; de Wreede, Liesbeth C (EBMT Statistics) ; Mufti, G. (GKT School of Medicine) ; Knelange, N. S. (EBMT Data Office) ; Niederwieser, D. (University Hospital Leipzig) ; Friis, L. S. (University of Copenhagen) ; Ehninger, Gerhard (Universitätsklinikum Dresden) ; Nagler, Arnon (Chaim Sheba Medical Center (Israel)) ; Yakoub-Agha, Ibrahim (Université Lille2) ; Meijer, E. (Amsterdam UMC. University Medical Center) ; Ljungman, Per (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Maertens, Johan (University Hospitals Gasthuisberg (Leuven, Bélgica)) ; Kanz, L. (Universität Tübingen) ; Lopez-Corral, L. (Hospital Clínico Universitario (Salamanca)) ; Brecht, A. (Deutsche Klinik für Diagnostik) ; Craddock, Charles (Centre for Clinical Haematology) ; Finke, J. (University of Freiburg) ; Cornelissen, J. J. (Erasmus MC Cancer Institute. Erasmus University Medical Center) ; Bernasconi, P. (Fondazione IRCCS Policlinico San Matteo) ; Chevallier, Patrice (CHU Nantes) ; Sierra, Jorge (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Robin, M. (Hopital St. Louis) ; Kroeger, Nicolaus (University Medical Center Hamburg-Eppendorf) ; Universitat Autònoma de Barcelona
The aim of this study was to develop and validate a clinical and transplant-specific prognostic score using data from a large cohort of patients with myelodysplastic syndromes reported to the European Society for Blood and Marrow Transplantation registry. [...]
2019 - 10.3324/haematol.2018.200808
Haematologica, Vol. 104 Núm. 5 (30 2019) , p. 929-936  
Detailed record - Creative Commons

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