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33 p, 2.0 MB |
Diagnosis and management of AML in adults : 2022 recommendations from an international expert panel on behalf of the ELN
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Döhner, Hartmut (Ulm University Hospital. Department of Internal Medicine III) ;
Wei, Andrew H. (Peter MacCallum Cancer Centre. Royal Melbourne Hospital and University of Melbourne. Department of Haematology) ;
Appelbaum, Frederick (University of Washington. Fred Hutchinson Cancer Research Center) ;
Craddock, Charles (Centre for Clinical Haematology. Queen Elizabeth Hospital. University of Birminham) ;
DiNardo, Courtney D. (The University of Texas MD Anderson Cancer Center. Department of Leukemia) ;
Dombret, Hervé (Saint-Louis Institute for Research. Université de Paris. Hôpital Saint-Louis. Assistance Publique-Hôpitaux de Paris. Department of Hematology) ;
Ebert, Benjamin L. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Fenaux, Pierre (Service d'Hématologie Séniors. Hôpital Saint-Louis. Assistance Publique-Hôpitaux de Paris) ;
Godley, Lucy A. (The University of Chicago. Section of Hematology/Oncology. Department of Medicine) ;
Hasserjian, Robert P (Massachusetts General Hospital) ;
Larson, Richard A (University of Chicago. Department of Medicine and Comprehensive Cancer Center) ;
Levine, Ross L. (Memorial Sloan Kettering Cancer Center. Human Oncology and Pathogenesis Program and Leukemia Service. Department of Medicine) ;
Miyazaki, Yasushi (Atomic Bomb Disease Institute. Nagasaki University. Department of Hematology) ;
Niederwieser, Dietger (University of Leipzig) ;
Ossenkoppele, Gert (Department of Haematology. Amsterdam UMC. Location VU University Medical Center) ;
Röllig, Christoph (Department of Internal Medicine I. University Hospital Carl Gustav Carus TU Dresden) ;
Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ;
Stein, Eytan M. (Leukemia Service. Department of Medicine. Memorial Sloan Kettering Cancer Center) ;
Tallman, Martin S. (Leukemia Service. Department of Medicine. Memorial Sloan Kettering Cancer Center) ;
Tien, Hwei-Fang F. (Division of Hematology. Department of Internal Medicine. National Taiwan University Hospital) ;
Wang, Jianxiang (Institute of Hematology and Blood Diseases Hospital. Chinese Academy of Medical Sciences & Peking Union Medical College) ;
Wierzbowska, Agnieszka (Department of Hematology. Medical University of Lodz) ;
Löwenberg, Bob (Department of Hematology. Erasmus University Medical Center Rotterdam and Erasmus MC Cancer Institute)
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults are widely recognized among physicians and investigators. [...]
2022 -  10.1182/blood.2022016867
Blood, Vol. 140 Núm. 12 (september 2022) , p. 1345-1377
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7 p, 363.5 KB |
The EHA Research Roadmap : Malignant Myeloid Diseases
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Döhner, Hartmut (Department of Internal Medicine III. Ulm University Hospital) ;
Malcovati, Luca (Istituto di Ricovero e Cura A Carattere Scientifico (IRCCS)) ;
Ossenkoppele, Gert J. (Amsterdam UMC. Department of Hematology. VU University. Medical Center) ;
Hochhaus, Andreas (Universitätsklinikum Jena. Klinik für Innere Medizin II. Hämatologie/Onkologie) ;
Maria Vannucchi, Alessandro (Center Research and Innovation of Myeloproliferative Neoplasms. CRIMM. University of Florence) ;
Bullinger, Lars (Freie Universität Berlin) ;
Cervantes, Francisco (Hospital Clínic i Provincial de Barcelona) ;
Craddock, Charles (Centre for Clinical Haematology. Queen Elizabeth Hospital) ;
de Witte, Theo. (Radboud University. Medical Centre. Nijmegen) ;
Döhner, Konstanze (Department of Internal Medicine III. Ulm University Hospital) ;
Dombret, Hervé (Institut de Recherche Saint-Louis (IRSL). Université de Paris. Hôpital Saint-Louis) ;
Fenaux, Pierre (Département (DMU) d'Hématologie et Immunologie. Assistance Publique Hôpitaux de Paris. Hôpital St Louis. Université de Paris) ;
Geissler, Jan (Leukemia Patient Advocates Foundation) ;
Germing, Ulrich (Klinik für Hämatologie. Onkologie und Klinische Immunologie. Universitätsklinikum Düsseldorf. Heinrich-Heine Universität Düsseldorf) ;
Guilhot, Francois (University of Poitiers) ;
Harrison, Claire (Department of Haematology. Guys and St thomas'Hospital) ;
Hellström-Lindberg, Eva (Karolinska Institutet (Estocolm, Suècia)) ;
Passamonti, Francesco (Department of Clinical and Biological Sciences. University of Turin. San Luigi University Hospital) ;
Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ;
Skoda, Radek (University Hospital Basel (Basilea, Suïssa)) ;
Wierzbowska, Agnieszka. (Multi-specialized Center of Oncology and Traumatology)
In 2016, the European Hematology Association (EHA) published the EHA Roadmap for European Hematology Research1 aiming to highlight achievements in the diagnostics and treatment of blood disorders, and to better inform European policy makers and other stakeholders about the urgent clinical and scientific needs and priorities in the field of hematology. [...]
2021 - 10.1097/HS9.0000000000000635
HemaSphere, Vol. 5 Núm. 9 (2021)
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3.
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1.2 MB |
Molecular landscape and prognostic impact of FLT3 -ITD insertion site in acute myeloid leukemia : RATIFY study results
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Rücker, Frank G. (University Hospital of Ulm (Alemanya)) ;
Du, Ling (Novartis Pharmaceuticals, Cambridge) ;
Luck, Tamara J. (Charité University, Berlin) ;
Benner, Axel (German Cancer Research Center, Heidelberg) ;
Krzykalla, Julia (German Cancer Research Center, Heidelberg) ;
Gathmann, Insa (Novartis Pharmaceuticals, Basel) ;
Voso, Maria Teresa (Università di Roma "Tor Vergata", Rome) ;
Amadori, Sergio (Università di Roma "Tor Vergata", Rome) ;
Prior, Thomas W. (The Ohio State University Comprehensive Cancer Center, Columbus) ;
Brandwein, Joseph M. (University of Alberta, Edmonton) ;
Appelbaum, Frederick (Fred Hutchinson Cancer Research Center, Seattle) ;
Medeiros, Bruno (Stanford University) ;
Tallman, Martin S. (Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York) ;
Savoie, Lynn (University of Calgary, Calgary) ;
Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ;
Pallaud, Celine (Novartis Pharmaceuticals, Basel) ;
Sanz, Miguel A.. (Hospital Universitari i Politècnic La Fe (València)) ;
Jansen, Joop H. (Radboud University Medical Center, Nijmegen) ;
Niederwieser, Dietger (Hematology and Oncology, University of Leipzig, Leipzig) ;
Fischer, Thomas (Otto-von-Guericke University Magdeburg, Magdeburg) ;
Ehninger, Gerhard (Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden) ;
Heuser, Michael (Hannover Medical School, Hannover) ;
Ganser, Arnold (Oncology and Stem Cell Transplantation, Hannover) ;
Bullinger, Lars (Charité University, Berlin) ;
Larson, Richard A. (University of Chicago, Chicago) ;
Bloomfield, Clara D. (The Ohio State University Comprehensive Cancer Center, Columbus) ;
Stone, Richard M. (Dana-Farber/Partners CancerCare, Boston) ;
Döhner, Hartmut (University Hospital of Ulm (Alemanya)) ;
Thiede, Christian (Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden) ;
Döhner, Konstanze (University Hospital of Ulm (Alemanya)) ;
Universitat Autònoma de Barcelona
In acute myeloid leukemia (AML) internal tandem duplications of the FLT3 gene (FLT3- ITD) are associated with poor prognosis. Retrospectively, we investigated the prognostic and predictive impact of FLT3 -ITD insertion site (IS) in 452 patients randomized within the RATIFY trial, which evaluated midostaurin additionally to intensive chemotherapy. [...]
2021 - 10.1038/s41375-021-01323-0
Leukemia, Vol. 36 (july 2021) , p. 90-99
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