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Articles, 2 records found
Articles 2 records found  
1.
33 p, 2.0 MB Diagnosis and management of AML in adults : 2022 recommendations from an international expert panel on behalf of the ELN / Döhner, Hartmut (Ulm University Hospital. Department of Internal Medicine III) ; Wei, Andrew H. (Peter MacCallum Cancer Centre. Royal Melbourne Hospital and University of Melbourne. Department of Haematology) ; Appelbaum, Frederick (University of Washington. Fred Hutchinson Cancer Research Center) ; Craddock, Charles (Centre for Clinical Haematology. Queen Elizabeth Hospital. University of Birminham) ; DiNardo, Courtney D. (The University of Texas MD Anderson Cancer Center. Department of Leukemia) ; Dombret, Hervé (Saint-Louis Institute for Research. Université de Paris. Hôpital Saint-Louis. Assistance Publique-Hôpitaux de Paris. Department of Hematology) ; Ebert, Benjamin L. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; Fenaux, Pierre (Service d'Hématologie Séniors. Hôpital Saint-Louis. Assistance Publique-Hôpitaux de Paris) ; Godley, Lucy A. (The University of Chicago. Section of Hematology/Oncology. Department of Medicine) ; Hasserjian, Robert P (Massachusetts General Hospital) ; Larson, Richard A (University of Chicago. Department of Medicine and Comprehensive Cancer Center) ; Levine, Ross L. (Memorial Sloan Kettering Cancer Center. Human Oncology and Pathogenesis Program and Leukemia Service. Department of Medicine) ; Miyazaki, Yasushi (Atomic Bomb Disease Institute. Nagasaki University. Department of Hematology) ; Niederwieser, Dietger (University of Leipzig) ; Ossenkoppele, Gert (Department of Haematology. Amsterdam UMC. Location VU University Medical Center) ; Röllig, Christoph (Department of Internal Medicine I. University Hospital Carl Gustav Carus TU Dresden) ; Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ; Stein, Eytan M. (Leukemia Service. Department of Medicine. Memorial Sloan Kettering Cancer Center) ; Tallman, Martin S. (Leukemia Service. Department of Medicine. Memorial Sloan Kettering Cancer Center) ; Tien, Hwei-Fang F. (Division of Hematology. Department of Internal Medicine. National Taiwan University Hospital) ; Wang, Jianxiang (Institute of Hematology and Blood Diseases Hospital. Chinese Academy of Medical Sciences & Peking Union Medical College) ; Wierzbowska, Agnieszka (Department of Hematology. Medical University of Lodz) ; Löwenberg, Bob (Department of Hematology. Erasmus University Medical Center Rotterdam and Erasmus MC Cancer Institute)
The 2010 and 2017 editions of the European LeukemiaNet (ELN) recommendations for diagnosis and management of acute myeloid leukemia (AML) in adults are widely recognized among physicians and investigators. [...]
2022 - 10.1182/blood.2022016867
Blood, Vol. 140 Núm. 12 (september 2022) , p. 1345-1377  
2.
12 p, 506.4 KB Results from a First-in-Human Phase I Study of Siremadlin (HDM201) in Patients with Advanced Wild-Type TP53 Solid Tumors and Acute Leukemia / Stein, Eytan M. (Memorial Sloan Kettering Cancer Center (New York)) ; DeAngelo, Daniel J. (Dana-Farber Cancer Institute (Boston, Massachusetts)) ; Chromik, Jörg (Goethe University Frankfurt) ; Chatterjee, Manik (University Hospital of Würzburg) ; Bauer, Sebastian (German Consortium of Translational Cancer Research (DKTK)) ; Lin, Chia-Chi (National Taiwan University Hospital (Taipei, Taiwan)) ; Suárez, Cristina (Vall d'Hebron Institut d'Oncologia) ; de Vos, Filip (University Medical Center Utrecht) ; Steeghs, Neeltje (The Netherlands Cancer Institute (Amsterdam, Països Baixos)) ; Cassier, Philippe A. (Léon Bérard Center) ; Tai, David (National Cancer Center Singapore) ; Kiladjian, Jean-Jacques (Université de Paris) ; Yamamoto, Noboru (National Cancer Center Hospital (Tokyo, Japó)) ; Mous, Rogier (University Medical Center Utrecht) ; Esteve Reyner, Jordi (Hospital Clínic i Provincial de Barcelona) ; Minami, Hironobu (Kobe University Graduate School of Medicine and Hospital (Japó)) ; Ferretti, Stephane (Novartis Institutes for Biomedical Research) ; Guerreiro, Nelson (Novartis Institutes for Biomedical Research) ; Meille, Christophe (Novartis Institutes for Biomedical Research) ; Radhakrishnan, Rajkumar (Novartis Healthcare Private Limited (Hyderabad, India)) ; Pereira, Bernard (Novartis Institutes for BioMedical Research (Cambridge, Massachusetts)) ; Mariconti, Luisa (Novartis Institutes for Biomedical Research) ; Halilovic, Ensar (Novartis Institutes for BioMedical Research (Cambridge, Massachusetts)) ; Fabre, Claire (Novartis Institutes for Biomedical Research) ; Carpio Segura, Cecilia del Carmen (Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona
This phase I, dose-escalation study investigated the recommended dose for expansion (RDE) of siremadlin, a p53-MDM2 inhibitor, in patients with wild-type TP53 advanced solid or hematologic cancers. Initial dosing regimens were: 1A (day 1; 21-day cycle; dose 12. [...]
2021 - 10.1158/1078-0432.CCR-21-1295
Clinical Cancer Research, Vol. 28 (december 2021) , p. 870-881  

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1 Stein, E.A.
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