Jacobson, Kenneth A - Resultados de la búsqueda - Depósito Digital de Documentos de la UAB

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Artículos	Encontrados 4 registros

12 p, 2.9 MB

Adenosine a2a receptors are upregulated in peripheral blood mononuclear cells from atrial fibrillation patients / Godoy-Marín, H. (Institut d'Investigació Biomèdica de Bellvitge) ; Duroux, R. (Molecular Recognition Section. Laboratory of Bioorganic Chemistry. National Institute of Diabetes and Digestive and Kidney Diseases. National Institutes of Health) ; Jacobson, Kenneth A (Molecular Recognition Section. Laboratory of Bioorganic Chemistry. National Institute of Diabetes and Digestive and Kidney Diseases. National Institutes of Health) ; Soler, C. (Universitat de Barcelona) ; Colino-Lage, Hildegard (Institut d'Investigacions Biomèdiques de Barcelona) ; Jiménez-Sábado, Verónica (Institut d'Investigació Biomèdica Sant Pau) ; Montiel, José (Institut d'Investigació Biomèdica Sant Pau) ; Hove-Madsen, Leif (Institut d'Investigació Biomèdica Sant Pau) ; Ciruela, Francisco (Institut d'Investigació Biomèdica de Bellvitge)
Atrial fibrillation (AF) is the most common form of cardiac arrhythmia seen in clinical practice. While some clinical parameters may predict the transition from paroxysmal to persistent AF, the molecular mechanisms behind the AF perpetuation are poorly understood. [...]
2021 - DOI (Digital Object Identifier)

10.3390/ijms22073467
International journal of molecular sciences, Vol. 22 Núm. 7 (january 2021) , p. 3467

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18 p, 826.7 KB

Remote control of movement disorders using a photoactive adenosine A 2A receptor antagonist / Taura, Jaume (Universitat de Barcelona. Institut de Neurociències) ; Nolen, Ernest G. (Colgate University) ; Cabré Segura, Gisela (Universitat Autònoma de Barcelona. Departament de Química) ; Hernando Campos, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ; Squarcialupi, Lucia (National Institutes of Health. National Institute of Diabetes and Digestive and Kidney Diseases (USA)) ; López Cano, Marc (Universitat de Barcelona. Institut de Neurociències) ; Jacobson, Kenneth A. (National Institutes of Health. National Institute of Diabetes and Digestive and Kidney Diseases (USA)) ; Fernández-Dueñas, Víctor (Universitat de Barcelona. Institut de Neurociències) ; Ciruela, Francisco (Universitat de Barcelona. Institut de Neurociències)
G protein-coupled adenosine receptors are promising therapeutic targets for a wide range of neuropathological conditions, including Parkinson's disease (PD). However, the ubiquity of adenosine receptors and the ultimate lack of selectivity of certain adenosine-based drugs have frequently diminished their therapeutic use. [...]
2018 - DOI (Digital Object Identifier)

10.1016/j.jconrel.2018.05.033
Journal of Controlled Release, Vol. 283 (August 2018) , p. 135-142

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17 p, 1000.6 KB

Optical control of adenosine A3 receptor function in psoriasis / López-Cano, Marc (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Filgaira, Ingrid (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Nolen, Ernest G. (Colgate University) ; Cabré Segura, Gisela (Universitat Autònoma de Barcelona. Departament de Química) ; Hernando Campos, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ; Tosh, Dilip K. (National Institutes of Health. National Institute of Diabetes and Digestive and Kidney Diseases (USA)) ; Jacobson, Kenneth A. (National Institutes of Health. National Institute of Diabetes and Digestive and Kidney Diseases (USA)) ; Soler, Concepció (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Ciruela, Francisco (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental)
Psoriasis is a chronic and relapsing inflammatory skin disease lacking a cure that affects approximately 2% of the population. Defective keratinocyte proliferation and differentiation, and aberrant immune responses are major factors in its pathogenesis. [...]
2021 - DOI (Digital Object Identifier)

10.1016/j.phrs.2021.105731
Pharmacological Research, Vol. 170 (August 2021) , art. 105731

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8 p, 1.6 MB

Photomodulation of G protein-coupled adenosine receptors by a novel light-switchable ligand / Bahamonde, María Isabel (Institut de Bioenginyeria de Catalunya) ; Taura, Jaume (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Paoletta, Silvia (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Gakh, Anadrei A. (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Chakraborty, Saibal (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Hernando Campos, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ; Fernández-Dueñas, Víctor (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental) ; Jacobson, Kenneth A. (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ; Gorostiza, Pau (Institut de Bioenginyeria de Catalunya) ; Ciruela, Francisco (Universitat de Barcelona. Departament de Patologia i Terapèutica Experimental)
The adenosinergic system operates through G protein-coupled adenosine receptors, which have become promising therapeutic targets for a wide range of pathological conditions. However, the ubiquity of adenosine receptors and the eventual lack of selectivity of adenosine-based drugs have frequently diminished their therapeutic potential. [...]
2014 - DOI (Digital Object Identifier)

10.1021/bc5003373
Bioconjugate chemistry, Vol. 25, Issue 10 (October 2014) , p. 1847-1854

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3	Jacobson, Kenneth A.
1	Jacobson, Kirstine

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