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1.
11 p, 3.4 MB PIVOT-12 : a phase III study of adjuvant bempegaldesleukin plus nivolumab in resected stage III/IV melanoma at high risk for recurrence / Eggermont, Alexander M. (Princess Máxima Center for Pediatric Oncology & University Medical Center Utrecht) ; Ascierto, Paolo A. (Istituto Nazionale Tumori IRCCS Fondazione G Pascale) ; Khushalani, Nikhil I. (H Lee Moffitt Cancer Center & Research Institute) ; Schadendorf, Dirk (West German Cancer Center at the University Hospital Essen) ; Boland, Genevieve (Massachusetts General Hospital (Boston)) ; Weber, Jeffrey (Perlmutter Cancer Center at NYU Langone Health) ; Lewis, Karl D. (University of Colorado Cancer Center) ; Johnson, Daniel (Ochsner Medical Center) ; Rivalland, Gareth (University of Auckland & Auckland City Hospital) ; Khattak, Adnan (Hollywood Private Hospital. Edith Cowan University) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Gogas, Helen (National & Kapodistrian University of Athens) ; Long, Georgina V. (Melanoma Institute Australia. University of Sydney. Royal North Shore & Mater Hospitals) ; Currie, Sue L. (Nektar Therapeutics, San Francisco, CA 94158, USA) ; Chien, David (Nektar Therapeutics, San Francisco, CA 94158, USA) ; Tagliaferri, Mary A. (Nektar Therapeutics, San Francisco, CA 94158, USA) ; Carlino, Matteo S. (Westmead & Blacktown Hospitals & Melanoma Institute Australia. University of Sydney) ; Diab, Adi (University of Texas MD Anderson Cancer Center)
Bempegaldesleukin (BEMPEG: NKTR-214) is an immunostimulatory IL-2 cytokine prodrug engineered to deliver a controlled, sustained and preferential IL-2 pathway signal. Nivolumab (NIVO), a PD-1 inhibitor, has been shown to prolong survival in patients with advanced melanoma and recurrence-free survival in the adjuvant setting. [...]
2022 - 10.2217/fon-2021-1286
Future oncology (London, England), Vol. 18 Núm. 8 (january 2022) , p. 903-913  
2.
35 p, 1.4 MB Weak tradeoff between xylem safety and xylem-specific hydraulic efficiency across the world's woody plant species / Gleason, Sean M. (Macquarie University. Department of Biological Sciences) ; Westoby, Mark (Macquarie University. Department of Biological Sciences) ; Jansen, Steven (University of Ulm. Institute of Systematic Botany and Ecology) ; Choat, Brendan (University of Western Sydney. Hawkesbury Institute for the Environment) ; Hacke, Uwe G. (University of Alberta. Department of Renewable Resource) ; Pratt, Robert B. (California State University, Bakersfield. Department of Biology) ; Bhaskar, Radika (Haverford College. Department of Biology) ; Brodribb, Tim J. (University of Tasmania. School of Biological Sciences) ; Bucci, Sandra J. (Universidad Nacional de la Patagonia San Juan Bosco. Grupo de Estudios Biofısicos y Eco-fisiológicos) ; Cao, Kun-Fang (Guangxi da xue. Plant Ecophysiology and Evolution Group) ; Cochard, Hervé (Institut National de la Recherche Agronomique (França)) ; Delzon, Sylvain (Institut National de la Recherche Agronomique (França)) ; Domec, Jean-Christophe (Institut National de la Recherche Agronomique (França)) ; Fan, Ze-Xin (Chinese Academy of Sciences. Xishuangbanna Tropical Botanical Garden) ; Feild, Taylor S. (James Cook University of North Queensland. School of Marine and Tropical Biology) ; Jacobsen, Anna L. (California State University, Bakersfield. Department of Biology) ; Johnson, Daniel M. (University of Idaho. Department of Forest, Rangeland and Fire Sciences) ; Lens, Frederic (Rijksuniversiteit te Leiden. Naturalis Biodiversity Center) ; Maherali, Hafiz (University of Guelph (Canadà). Department of Integrative Biology) ; Martínez Vilalta, Jordi, 1975- (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Mayr, Stefan (Universität Innsbruck. Institut für Botanik) ; McCulloh, Katherine A. (University of Wisconsin-Madison. Department of Botany) ; Mencuccini, Maurizio (University of Edinburgh. School ofGeoSciences) ; Mitchell, Patrick J. (CSIRO (Australia). Land and Water) ; Morris, Hugh (University of Ulm. Institute of Systematic Botany and Ecology) ; Nardini, Andrea (Università degli studi di Trieste. Dipartimento Scienze della Vita) ; Pittermann, Jarmila (University of California. Department of Ecology and Evolutionary Biology) ; Plavcová, Lenka (University of Alberta. Department of Renewable Resource) ; Schreiber, Stefan G. (University of Alberta. Department of Renewable Resource) ; Sperry, John S. (University of Utah. Biology Department) ; Wright, Ian J. (Macquarie University. Department of Biological Sciences) ; Zanne, A. E (George Washington University. Department of Biological Sciences)
The evolution of lignified xylem allowed for the efficient transport of water under tension, but also exposed the vascular network to the risk of gas emboli and the spread of gas between xylem conduits, thus impeding sap transport to the leaves. [...]
2016 - 10.1111/nph.13646
The new phytologist, Vol. 209, Issue 1 (Jan. 2016) , p. 123-136
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