Lynam, Lorna - Search Results - UAB Digital Repository of Documents

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16 p, 3.1 MB

Ursolic Acid Inhibits Collective Cell Migration and Promotes JNK-Dependent Lysosomal Associated Cell Death in Glioblastoma Multiforme Cells / Conway, Gillian E. (In-Vitro Toxicology Group, Institute of Life Science, Swansea University Medical School) ; Zizyte, Deimante (School of Food Science and Environmental Health, Technological University Dublin) ; Mondala, Julie Rose Mae (School of Food Science and Environmental Health, Technological University Dublin) ; He, Zhonglei (Environmental Sustainability and Health Institute (ESHI) and FOCAS Research Institute, Technological University Dublin) ; Lynam, Lorna (School of Food Science and Environmental Health, Technological University Dublin) ; Lecourt, Mathilde (School of Food Science and Environmental Health, Technological University Dublin) ; Barcia, Carlos (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Howe, Orla (School of Biological Sciences and Health Sciences, Technological University Dublin) ; Curtin, James (Dublin Institute of Technology. School of Food Science and Environmental Health)
Ursolic acid (UA) is a bioactive compound which has demonstrated therapeutic efficacy in a variety of cancer cell lines. UA activates various signalling pathways in Glioblastoma multiforme (GBM) and offers a promising starting point in drug discovery; however, understanding the relationship between cell death and migration has yet to be elucidated. [...]
2021 - DOI (Digital Object Identifier)

10.3390/ph14020091
Pharmaceuticals, Vol. 14 (january 2021)

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