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Articles, 2 records found
Articles 2 records found  
1.
16 p, 1.2 MB Inhibition of Prolyl Oligopeptidase Restores Prohibitin 2 Levels in Psychosis Models : Relationship to Cognitive Deficits in Schizophrenia / Vila, Èlia (Institut de Recerca Sant Joan de Déu) ; Pinacho, Raquel (Institut de Recerca Sant Joan de Déu) ; Prades, Roger (Iproteos S.L.) ; Tarragó, Teresa (Iproteos S.L.) ; Castro Fernánez, Elena (Institut de Salut Carlos III) ; Munarriz-Cuezva, Eva (Institut de Salut Carlos III) ; Meana, J. Javier (Institut de Salut Carlos III) ; Eugui-Anta, Ania (Institut de Recerca Sant Joan de Déu) ; Roldan Molina, Mònica (Hospital Sant Joan de Déu (Manresa)) ; Vera-Montecinos, América (Institut de Recerca Sant Joan de Déu) ; Ramos, Belén (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Cognitive impairment represents one of the core features of schizophrenia. Prolyl Oligopeptidase (POP) inhibition is an emerging strategy for compensating cognitive deficits in hypoglutamatergic states such as schizophrenia, although little is known about how POP inhibitors exert their pharmacological activity. [...]
2023 - 10.3390/ijms24076016
International journal of molecular sciences, Vol. 24 (march 2023)  
Detailed record - Creative Commons
2.
22 p, 1.2 MB Calcium-binding proteins are altered in the cerebellum in schizophrenia / Vidal-Domènech, Francisco (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Riquelme, Gemma (Institut de Recerca Sant Joan de Déu) ; Pinacho, Raquel (Institut de Recerca Sant Joan de Déu) ; Rodríguez-Mias, Ricard (University of Washington) ; Vera, América (Institut de Recerca Sant Joan de Déu) ; Monje, Alfonso (Parc Sanitari Sant Joan de Déu) ; Ferrer, Isidro (Institut d'Investigació Biomèdica de Bellvitge) ; Callado, Luis F. (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Meana, J. Javier (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Villén, Judit (University of Washington) ; Ramos, Belén (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Alterations in the cortico-cerebellar-thalamic-cortical circuit might underlie the diversity of symptoms in schizophrenia. However, molecular changes in cerebellar neuronal circuits, part of this network, have not yet been fully determined. [...]
2020 - 10.1371/journal.pone.0230400
PloS one, Vol. 15, Num. 7 (July 2020) , art. e0230400  
Detailed record - Creative Commons

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