Home > Search Results: Reichenspurner, H.
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17 p, 2.1 MB Abnormal calcium handling in atrial fibrillation is linked to changes in cyclic amp dependent signaling / Reinhardt, F. (German Center for Cardiovascular Research (DZHK). Partner Site Hamburg/Kiel/Lübeck) ; Beneke, K. (Institute of Experimental Cardiovascular Research. University Medical Center Hamburg-Eppendorf (UKE)) ; Pavlidou, N. G. (Institute of Experimental Cardiovascular Research. University Medical Center Hamburg-Eppendorf (UKE)) ; Conradi, L. (Department of Cardiovascular Surgery. University Heart & Vascular Center Hamburg UKE) ; Reichenspurner, H. (Institute of Experimental Cardiovascular Research. University Medical Center Hamburg-Eppendorf (UKE)) ; Hove-Madsen, Leif (Institut d'Investigació Biomèdica Sant Pau) ; Molina, Cristina E. (Institute of Experimental Cardiovascular Research. University Medical Center Hamburg-Eppendorf (UKE)) ; Universitat Autònoma de Barcelona
Both, the decreased L-type Ca current (I) density and increased spontaneous Ca release from the sarcoplasmic reticulum (SR), have been associated with atrial fibrillation (AF). In this study, we tested the hypothesis that remodeling of 3,5-cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) signaling is linked to these compartment-specific changes (up-or down-regulation) in Ca-handling. [...]
2021 - 10.3390/cells10113042
Cells, Vol. 10 Núm. 11 (november 2021) , p. 3042  
Detailed record - Creative Commons

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