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Artículos, Encontrados 2 registros
Artículos Encontrados 2 registros  
1.
33 p, 20.4 MB Hyaluronic acid-GPRC5C signalling promotes dormancy in haematopoietic stem cells / Zhang, Yu Wei (University of Freiburg, Germany) ; Mess, Julian (University of Freiburg, Germany) ; Aizarani, Nadim (University of Freiburg, Germany) ; Mishra, Pankaj (University of Freiburg, Germany) ; Johnson, Carys (University of Cambridge, UK) ; Romero-Mulero, Mari Carmen (University of Freiburg, Germany) ; Rettkowski, Jasmin (University of Freiburg, Germany) ; Schönberger, Katharina (University of Freiburg, Germany) ; Obier, Nadine (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Jäcklein, Karin (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Woessner, Nadine M. (University of Freiburg, Germany) ; Lalioti, Maria Eleni (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Velasco-Hernandez, Talia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Sikora, Katarzyna (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Wäsch, Ralph (University of Freiburg, Germany) ; Lehnertz, Bernhard (University of Montreal, Canada) ; Sauvageau, Guy (University of Montreal, Canada) ; Manke, Thomas (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Menendez, Pablo (Institució Catalana de Recerca i Estudis Avançats) ; Walter, Sebastian Gottfried (University Hospital of Cologne, Germany) ; Minguet, Susana (University of Freiburg, Germany) ; Laurenti, Elisa (University of Cambridge, UK) ; Günther, Stefan (University of Freiburg, Germany) ; Grün, Dominic (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Cabezas-Wallscheid, Nina (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany)
Bone marrow haematopoietic stem cells (HSCs) are vital for lifelong maintenance of healthy haematopoiesis. In inbred mice housed in gnotobiotic facilities, the top of the haematopoietic hierarchy is occupied by dormant HSCs, which reversibly exit quiescence during stress. [...]
2022 - 10.1038/s41556-022-00931-x
Nature Cell Biology, Vol. 24 Núm. 7 (july 2022) , p. 1038-1048  
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2.
14 p, 2.7 MB GPRC5C drives branched-chain amino acid metabolism in leukemogenesis / Zhang, Yu Wei (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Velasco-Hernández, Talia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Mess, Julian (University of Freiburg) ; Lalioti, Maria Eleni (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Romero-Mulero, Mari Carmen (University of Freiburg, Germany) ; Obier, Nadine (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Karantzelis, Nikolaos (University Medical Center Freiburg, Germany) ; Rettkowski, Jasmin (University of Freiburg, Germany) ; Schönberger, Katharina (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Karabacz, Noemie (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Jäcklein, Karin (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany) ; Morishima, Tatsuya (Kumamoto University, Japan) ; Trincado Alonso, Juan Luis, 1987- (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Romecin, Paola (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Martinez, Alba (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Takizawa, Hitoshi (Kumamoto University, Japan) ; Shoumariyeh, Khalid (University of Freiburg, Germany) ; Renders, Simon (Heidelberg University Hospital (Alemanya)) ; Zeiser, Robert (University of Freiburg, Germany) ; Pahl, Heike L. (University Medical Center Freiburg, Germany) ; Béliveau, François (Quebec leukemia cell bank. Hopital Maisonneuve-Rosemont, Montreal, Canada) ; Hébert, Josee (Quebec leukemia cell bank. Hopital Maisonneuve-Rosemont, Montreal, Canada) ; Lehnertz, Bernhard (University of Montreal, Canada) ; Sauvageau, Guy (University of Montreal, Canada) ; Menendez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Cabezas-Wallscheid, Nina (Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany)
Leukemia stem cells (LSCs) share numerous features with healthy hematopoietic stem cells (HSCs). G-protein coupled receptor family C group 5 member C (GPRC5C) is a regulator of HSC dormancy. However, GPRC5C functionality in acute myeloid leukemia (AML) is yet to be determined. [...]
2023 - 10.1182/bloodadvances.2023010460
Blood advances, Vol. 7 Núm. 24 (december 2023) , p. 7525-7538  
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