Results overview: Found 5 records in 0.02 seconds.
Articles, 5 records found
Articles 5 records found  
1.
58 p, 970.8 KB RiboTag : Ribosomal tagging strategy to analyze cell type specific mRNA expression in vivo / Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bean, Jonathan C. (University of Washington. Department of Pharmacology) ; Carey, Daniel P. (University of Washington. Department of Pharmacology) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; McKnight, G. Stanley (University of Washington. Department of Pharmacology)
Ribosome tagging has become a very useful in vivo approach for analyzing gene expression and mRNA translation in specific cell types that are difficult and time consuming to isolate by conventional methods. [...]
2019 - 10.1002/cpns.77
Current Protocols in Neuroscience, 2019  
2.
9 p, 846.3 KB Striatal GPR88 modulates foraging efficiency / Rainwater, Aundrea (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Palmiter, Richard D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències)
The striatum is anatomically and behaviorally implicated in behaviors that promote efficient foraging. To investigate this function, we studied instrumental choice behavior in mice lacking GPR88, a striatum-enriched orphan G-protein-coupled receptor that modulates striatal medium spiny neuron excitability. [...]
2017 - 10.1523/JNEUROSCI.2439-16.2017
The Journal of Neuroscience, Vol. 37, Núm. 33 (August 2017) , p. 7939-7947  
3.
8 p, 2.2 MB Loss of mitochondrial Ndufs4 in striatal medium spiny neurons mediates progressive motor impairment in a mouse model of leigh syndrome / Chen, Byron (University of Washington. Howard Hughes Medical Institute) ; Hui, Jessica (Seattle Children's Research Institute (Seattle, Estats Units d'Amèrica)) ; Montgomery, Kelsey S. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gella, Alejandro (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bolea Tomás, Irene (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Palmiter, Richard D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències)
Inability of mitochondria to generate energy leads to severe and often fatal myoencephalopathies. Among these, Leigh syndrome (LS) is one of the most common childhood mitochondrial diseases; it is characterized by hypotonia, failure to thrive, respiratory insufficiency and progressive mental and motor dysfunction, leading to early death. [...]
2017 - 10.3389/fnmol.2017.00265
Frontiers in molecular neuroscience, Vol. 10 (August 2017) , article 265  
4.
16 p, 7.0 MB RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo. / Sanz Iglesias, Elisenda (University of Washington. Department of Pharmacology) ; Evanoff, Ryan (Washington State University. School of Molecular Biosciences) ; Quintana Romero, Albert (University of Washington. Department of Biochemistry) ; Evans, Elizabeth (Washington State University. School of Molecular Biosciences) ; Miller, Jeremy A. (Allen Institute for Brain Science (Seattle, Washington)) ; Ko, Chemyong (University of Illinois. Department of Comparative Biosciences) ; Amieux, Paul S. (University of Washington. Department of Pharmacology) ; Griswold, Michael D. (Washington State University. School of Molecular Biosciences) ; McKnight, G. Stanley (University of Washington. Department of Pharmacology)
Male spermatogenesis is a complex biological process that is regulated by hormonal signals from the hypothalamus (GnRH), the pituitary gonadotropins (LH and FSH) and the testis (androgens, inhibin). The two key somatic cell types of the testis, Leydig and Sertoli cells, respond to gonadotropins and androgens and regulate the development and maturation of fertilization competent spermatozoa. [...]
2013 - 10.1371/journal.pone.0066179
PLoS one, Vol. 8, Num. 6 (2013) , p. e66179  
5.
28 p, 14.2 MB Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state / Padilla, Stephanie L. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Qiu, Jian (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Soden, Marta E. (University of Washington (Seattle, Estats Units d'Amèrica)) ; Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Nestor, Casey C. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Barker, Forrest D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica)) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Zweifel, Larry S. (University of Washington (Seattle, Estats Units d'Amèrica)) ; Rønnekleiv, Oline K. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Kelly, Martin J. (Oregon Health and Science University (Oregon, Estats Units d'Amèrica)) ; Palmiter, Richard D. (Howard Hughes Medical Institute (Maryland, Estats Units d'Amèrica))
In the face of starvation, animals will engage in high-risk behaviors that would normally be considered maladaptive. Starving rodents, for example, will forage in areas that are more susceptible to predators and will also modulate aggressive behavior within a territory of limited or depleted nutrients. [...]
2016 - 10.1038/nn.4274
Nature neuroscience, Vol. 19, Num. 5 (May 2016) , p. 734-741  

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