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34 p, 950.5 KB |
Hematopoietic Cell Transplantation Outcomes in Monosomal Karyotype Myeloid Malignancies
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Pasquini, Marcelo (Medical College of Wisconsin) ;
Zhang, Mei-Jie (Medical College of Wisconsin) ;
Medeiros, Bruno (Stanford University School of Medicine) ;
Armand, Philippe (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Hu, Zhen-Huan (Medical College of Wisconsin) ;
Nishihori, Taiga (H. Lee Moffitt Cancer Center and Research Institute) ;
Aljurf, Mahmoud D. (King Faisal Specialist Hospital Center and Research) ;
Akpek, Görgün (Banner MD Anderson Cancer Center) ;
Cahn, Jean-Yves (University Hospital) ;
Cairo, Mitchell S. (New York Medical College) ;
Cerny, Jan (UMass Memorial Medical Center) ;
Copelan, Edward A. (Carolinas HealthCare System) ;
Deol, Abhinav (Wayne State University) ;
Freytes, César O. (University of Texas Health Science Center San Antonio) ;
Gale, Robert Peter (Imperial College London) ;
Ganguly, Siddhartha (University of Kansas Medical Center) ;
George, Biju (Christian Medical College) ;
Gupta, Vikas (University Health Network) ;
Hale, Gregory A. (All Children's Hospital) ;
Kamble, Rammurti T. (Baylor College of Medicine) ;
Klumpp, Thomas R. (Thomas Jefferson University Hospital) ;
Lazarus, Hillard M. (University Hospitals Case Medical Center) ;
Luger, Selina M. (University of Pennsylvania Medical Center) ;
Liesveld, Jane L. (University of Rochester Medical Center) ;
Litzow, Mark Robert (Mayo Clinic) ;
Marks, David I. (University Hospitals Bristol NHS Trust) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Norkin, Maxim (University of Florida College of Medicine) ;
Olsson, Richard F. (Uppsala University) ;
Oran, Betul (The University of Texas MD Anderson Cancer Center) ;
Pawarode, Attaphol (University of Michigan) ;
Pulsipher, Michael A. (University of Southern California Keck School of Medicine) ;
Ramanathan, Muthalagu (UMass Memorial Medical Center) ;
Reshef, Ran (University of Pennsylvania Medical Center) ;
Saad, Ayman A. (University of Alabama at Birmingham) ;
Saber, Wael (Medical College of Wisconsin) ;
Savani, Bipin N. (Vanderbilt University Medical Center) ;
Schouten, Harry C. (Academische Ziekenhuis) ;
Ringdén, Olle (Centre for Allogeneic Stem Cell Transplantation) ;
Tallman, Martin S. (Memorial Sloan Kettering Cancer Center) ;
Uy, Geoffrey L. (Washington University School of Medicine) ;
Wood, William A. (University of North Carolina) ;
Wirk, Baldeep (Seattle Cancer Care Alliance) ;
Pérez, Waleska S. (Medical College of Wisconsin) ;
Batiwalla, Minoo (National Heart Lung and Blood Institute - National Institutes of Health) ;
Weisdorf, Daniel J. (University of Minnesota Medical Center) ;
Universitat Autònoma de Barcelona
The presence of monosomal karyotype (MK+) in acute myeloid leukemia (AML) is associated with dismal outcomes. We evaluated the impact of MK+ in AML (MK+AML, n = 240) and in myelodysplastic syndrome (MDS) (MK+MDS, n = 221) on hematopoietic cell transplantation outcomes compared with other cytogenetically defined groups (AML, n = 3360; MDS, n = 1373) as reported to the Center for International Blood and Marrow Transplant Research from 1998 to 2011. [...]
2016 -  10.1016/j.bbmt.2015.08.024
Biology of blood and marrow transplantation, Vol. 22 Núm. 2 (january 2016) , p. 248-257
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9 p, 1.0 MB |
Improved survival after acute graft-versus-host disease diagnosis in the modern era
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Khoury, Hanna J. (Winship Cancer Institute of Emory University) ;
Wang, Tao (Medical College of Wisconsin) ;
Hemmer, Michael T. (Medical College of Wisconsin) ;
Couriel, Daniel (Utah Blood and Marrow Transplant) ;
Alousi, Amin (The University of Texas MD Anderson Cancer Center) ;
Cutler, Corey (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Aljurf, Mahmoud (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
Battiwalla, Minoo (Lung and Blood Institute-NIH) ;
Cahn, Jean-Yves (University Hospital) ;
Cairo, Mitchell (New York Medical College) ;
Chen, Yi-Bin (Massachusetts General Hospital) ;
Gale, Robert Peter (Imperial College London) ;
Hashmi, Shahrukh (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
Hayashi, Robert J. (Washington University School of Medicine in St. Louis) ;
Jagasia, Madan (Vanderbilt University Medical Center) ;
Juckett, Mark (University of Wisconsin Hospital and Clinics) ;
Kamble, Rammurti T. (Baylor College of Medicine) ;
Kharfan-Dabaja, Mohamed (H. Lee Moffitt Cancer Center and Research Institute) ;
Litzow, Mark (Mayo Clinic Rochester) ;
Majhail, Navnnet (Cleveland Clinic Taussig Cancer Institute) ;
Miller, Alan (Baylor College of Medicine) ;
Nishihori, Taiga (H. Lee Moffitt Cancer Center and Research Institute) ;
Qayed, Muna (Emory University School of Medicine) ;
Antin, Joseph H. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Schoemans, Helene (University Hospitals Leuven (Bèlgica)) ;
Schouten, Harry C. (Academische Ziekenhuis) ;
Socie, Gerard (Hopital Saint Louis) ;
Storek, Jan (University of Calgary) ;
Verdonck, Leo (Isala Clinics Zwolle) ;
Vij, Ravi (Washington University School of Medicine) ;
Wood, Willian A. (University of North Carolina) ;
Yu, Lolie (Children's Hospital/Louisiana State University Medical Center) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Carabasi, Matthew (Thomas Jefferson University Hospital) ;
Dandoy, Christopher (Cincinnati Children's Hospital Medical Center) ;
Gergis, Usama (New York Presbyterian Hospital/Weill Cornell Medical Center) ;
Hematti, Peiman (University of Wisconsin Hospital and Clinics) ;
Solh, Melham (The Blood and Marrow Transplant Group of Georgia) ;
Jamani, Kareem (University of Calgary) ;
Lehmann, Leslie (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ;
Savani, Bipin (Vanderbilt University Medical Center) ;
Schultz, Kirk R. (The University of British Columbia) ;
Wirk, Baldeep M. (Seattle Cancer Care Alliance) ;
Spellman, Stephen (Center for International Blood and Marrow Transplant Research) ;
Arora, Mukta (University of Minnesota Medical Center) ;
Pidala, Joseph (H. Lee Moffitt Cancer Center and Research Institute) ;
Universitat Autònoma de Barcelona
Acute graft-versus-host disease remains a major threat to a successful outcome after allogeneic hematopoietic cell transplantation. While improvements in treatment and supportive care have occurred, it is unknown whether these advances have resulted in improved outcome specifically among those diagnosed with acute graft-versus-host disease. [...]
2017 - 10.3324/haematol.2016.156356
Haematologica, Vol. 102 Núm. 5 (30 2017) , p. 958-966
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10 p, 680.7 KB |
Lower Graft-versus-Host Disease and Relapse Risk in Post-Transplant Cyclophosphamide-Based Haploidentical versus Matched Sibling Donor Reduced-Intensity Conditioning Transplant for Hodgkin Lymphoma
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Ahmed, Sairah (University of Texas) ;
Kanakry, Jennifer A. (National Institutes of Health (Bethesda, Estats Units d'Amèrica)) ;
Ahn, Kwang Woo (Medical College of Wisconsin) ;
Litovich, Carlos Alejandro (Medical College of Wisconsin) ;
Abdel-Azim, Hisham (University of Southern California Keck School of Medicine) ;
Aljurf, Mahmoud Deeb (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
Bacher, Vera Ulrike (Inselspital. Bern University Hospital) ;
Bejanyan, Nelli (Immunotherapy. Moffitt Cancer Center) ;
Cohen, Jonathon B. (Emory University School of Medicine) ;
Farooq, Umar (University of Iowa Hospitals and Clinics) ;
Fuchs, Ephraim Joseph (The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins) ;
Bolaños-Meade, Javier (The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins) ;
Ghosh, Nilanjan S. (Levine Cancer Institute. Atrium Health) ;
Herrera, Alex F. (City of Hope National Medical Center) ;
Hossain, Nasheed (Loyola University Chicago-Stritch School of Medicine) ;
Inwards, David (Mayo Clinic) ;
Kanate, Abraham Sebastian (West Virginia University) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Munshi, Pashna (Georgetown University Hospital) ;
Murthy, Hemant S. (University Florida College of Medicine) ;
Mussetti, Alberto (Institut Català d'Oncologia-Hospitalet) ;
Nieto, Yago (University of Texas) ;
Perales, Miguel-Angel (Memorial Sloan Kettering Cancer Center) ;
Romee, Rizwan (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Savani, Bipin N. (Vanderbilt University Medical Center) ;
Seo, Sachiko (Dokkyo Medical University) ;
Wirk, Baldeep Mona (Seattle Cancer Care Alliance) ;
Yared, Jean A. (University of Maryland) ;
Sureda, Anna (Institut Català d'Oncologia-Hospitalet) ;
Fenske, Timothy S. (Medical College of Wisconsin) ;
Hamadani, Mehdi (Medical College of Wisconsin) ;
Universitat Autònoma de Barcelona
Classic Hodgkin lymphoma (cHL) patients with relapsed or refractory disease may benefit from allogeneic hematopoietic cell transplantation (allo-HCT), but many lack a matched sibling donor (MSD). Herein, we compare outcomes of 2 reduced-intensity conditioning (RIC) HCT platforms in cHL: T cell-replete related donor haploidentical (haplo) HCT with a post-transplant cyclophosphamide (PTCy)-based approach versus an MSD/calcineurin inhibitor (CNI)-based approach. [...]
2019 - 10.1016/j.bbmt.2019.05.025
Biology of blood and marrow transplantation, Vol. 25 Núm. 9 (september 2019) , p. 1859-1868
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10 p, 523.7 KB |
Risk Factors for Graft-versus-Host Disease in Haploidentical Hematopoietic Cell Transplantation Using Post-Transplant Cyclophosphamide
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Im, Annie (University of Pittsburgh/UPMC Hillman Cancer Center) ;
Rashidi, Armin (University of Minnesota) ;
Wang, Tao (Medical College of Wisconsin) ;
Hemmer, Michael (Medical College of Wisconsin) ;
MacMillan, Margaret L. (University of Minnesota) ;
Pidala, Joseph (H. Lee Moffitt Cancer Center and Research Institute) ;
Jagasia, Madan (Vanderbilt University Medical Center) ;
Pavletic, Steven (National Cancer Institute of Bethesda) ;
Majhail, Navneet S. (Cleveland Clinic Taussig Cancer Institute) ;
Weisdorf, Daniel (University of Minnesota) ;
Abdel-Azim, Hisham (University of Southern California Keck School of Medicine) ;
Agrawal, Vaibhav (Indiana University School of Medicine) ;
Al-Homsi, A.Samer (New York University Langone Medical Center) ;
Aljurf, Mahmoud (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ;
Askar, Medhat (Baylor University Medical Center) ;
Auletta, Jeffery J (Nationwide Children's Hospital) ;
Bashey, Asad (Blood and Marrow Transplant Program at Northside Hospital) ;
Beitinjaneh, Amer (University of Miami) ;
Bhatt, Vijaya Raj (University of Nebraska Medical Center) ;
Byrne, Michael (Vanderbilt University Medical Center) ;
Cahn, Jean-Yves (CHU Grenoble Alpes) ;
Cairo, Mitchell S (New York Medical College) ;
Castillo, Paul (UF Health Shands Children's Hospital) ;
Cerny, Jan (University of Massachusetts Medical Center) ;
Chhabra, Saurabh (Medical College of Wisconsin) ;
Choe, Hannah (The Ohio State University Wexner Medical Center) ;
Ciurea, Stefan (The University of Texas MD Anderson Cancer Center) ;
Daly, Andrew (Tom Baker Cancer Center) ;
Perez, Miguel Angel Diaz (Hospital Infantil Universitario Nino Jesus) ;
Farhadfar, Nosha (University of Florida College of Medicine) ;
Gadalla, Shahinaz M. (NIH-NCI Clinical Genetics Branch) ;
Gale, Robert (Imperial College London) ;
Ganguly, Siddhartha (University of Kansas Health System) ;
Gergis, Usama (Thomas Jefferson University) ;
Hanna, Rabi (Cleveland Clinic Foundation) ;
Hematti, Peiman (University of Wisconsin) ;
Herzig, Roger (University of Kentucky Chandler Medical Center) ;
Hildebrandt, Gerhard C. (University of Kentucky) ;
Lad, Deepesh P. (Postgraduate Institute of Medical Education and Research) ;
Lee, Catherine (University of Utah) ;
Lehmann, Leslie (Dana-Farber Cancer Institute/Boston Children's Hospital) ;
Lekakis, Lazaros (University of Miami) ;
Kamble, Rammurti T. (Baylor College of Medicine) ;
Kharfan-Dabaja, Momamed A. (Mayo Clinic) ;
Khandelwal, Pooja (University of Cincinnati) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Murthy, Hemant S. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ;
Nishihori, Taiga (H. Lee Moffitt Cancer Center and Research Institute) ;
O'Brien, Tracey A. (Sydney Children's Hospital) ;
Olsson, Richard F. (Uppsala University) ;
Patel, Sagar S. (University of Utah) ;
Perales, Miguel-Angel (Memorial Sloan Kettering Cancer Center) ;
Prestidge, Tim (Starship Children's Hospital (Auckland, Nova Zelanda)) ;
Qayed, Muna (Emory University School of Medicine) ;
Romee, Rizwan (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ;
Schoemans, Hélène (University Hospitals Leuven (Bèlgica)) ;
Seo, Sachiko (Dokkyo Medical University) ;
Sharma, Akshay (St. Jude Children's Research Hospital (Memphis, Estats Units d'Amèrica)) ;
Solh, Melhem (Northside Hospital) ;
Strair, Roger (Rutgers University) ;
Teshima, Takanori (Hokkaido University Hospital) ;
Urbano-Ispizua, Alvaro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Van der Poel, Marjolein (Maastricht University Medical Center) ;
Vij, Ravi (Washington University School of Medicine) ;
Wagner, John L. (Thomas Jefferson University) ;
William, Basem (The Ohio State University) ;
Wirk, Baldeep (Penn State Cancer Institute) ;
Yared, Jean A. (University of Maryland) ;
Spellman, Steve R. (Medical College of Wisconsin) ;
Arora, Mukta (University of Minnesota Medical Center) ;
Hamilton, Betty K. (Cleveland Clinic Taussig Cancer Institute) ;
Universitat Autònoma de Barcelona
Post-transplant cyclophosphamide (PTCy) has significantly increased the successful use of haploidentical donors with a relatively low incidence of graft-versus-host disease (GVHD). Given its increasing use, we sought to determine risk factors for GVHD after haploidentical hematopoietic cell transplantation (haplo-HCT) using PTCy. [...]
2020 - 10.1016/j.bbmt.2020.05.001
Biology of blood and marrow transplantation, Vol. 26 Núm. 8 (august 2020) , p. 1459-1468
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