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Artículos, Encontrados 4 registros
Artículos Encontrados 4 registros  
1.
16 p, 1.0 MB The role of macroh2a histone variants in cancer / Hsu, Chen-Jen (Internal Medicine C. Greifswald University Medicine) ; Meers, Oliver (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Heidel, Florian H. (Leibniz Institute on Aging. Fritz-Lipmann Institute)
The epigenome regulates gene expression and provides a molecular memory of cellular events. A growing body of evidence has highlighted the importance of epigenetic regulation in physiological tissue homeostasis and malignant transformation. [...]
2021 - 10.3390/cancers13123003
Cancers, Vol. 13 Núm. 12 (february 2021) , p. 3003  
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2.
13 p, 2.4 MB Histone variant MacroH2A1 is downregulated in prostate cancer and influences malignant cell phenotype / Vieira-Silva, T. S. (Portuguese Oncology Institute of Porto (IPO Porto)) ; Monteiro-Reis, S. (Portuguese Oncology Institute of Porto (IPO Porto)) ; Barros-Silva, D. (Portuguese Oncology Institute of Porto (IPO Porto)) ; Ramalho-Carvalho, J. (Portuguese Oncology Institute of Porto (IPO Porto)) ; Graça, I. (Portuguese Oncology Institute of Porto (IPO Porto)) ; Carneiro, I. (Department of Pathology. Portuguese Oncology Institute of Porto (IPO Porto)) ; Martins, A. T. (Department of Pathology. Portuguese Oncology Institute of Porto (IPO Porto)) ; Oliveira, Jorge (IPO-Porto. Department of Urology) ; Antunes, L. (Portuguese Oncology Institute of Porto (IPO Porto). Department of Epidemiology) ; Hurtado-Bagès, Sarah (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Henrique, Rui (University of Porto. Department of Pathology and Molecular Immunology) ; Jerónimo, C. (University of Porto. Department of Pathology and Molecular Immunology) ; Universitat Autònoma de Barcelona
Background: Prostate cancer (PCa), a major cause of cancer-related morbidity and mortality worldwide and mostly asymptomatic at earliest stages, is characterized by disruption of genetic and epigenetic balance. [...]
2019 - 10.1186/s12935-019-0835-9
Cancer Cell International, Vol. 19 Núm. 1 (29 2019) , p. 112  
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3.
17 p, 1.9 MB The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner / Hurtado-Bagès, Sarah (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Posavec Marjanovic, Melanija (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Valero, Vanesa (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Malinverni, Roberto (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Corujo, David (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bouvet, Philippe (Centre National de la Recherche Scientifique (França)) ; Lavigne, A. C. (Center for Integrative Biology (CBI). LBME. University of Toulouse. UPS. CNRS) ; Bystricky, K. (Center for Integrative Biology (CBI). LBME. University of Toulouse. UPS. CNRS) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
MacroH2A histone variants have functions in differentiation, somatic cell reprogramming and cancer. However, at present, it is not clear how macroH2As affect gene regulation to exert these functions. [...]
2020 - 10.3390/cells9051109
Cells, Vol. 9 Núm. 5 (30 2020)  
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4.
25 p, 1.1 MB Post-Translational Modifications of H2A Histone Variants and Their Role in Cancer / Corujo, David (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Buschbeck, Marcus (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Histone variants are chromatin components that replace replication-coupled histones in a fraction of nucleosomes and confer particular characteristics to chromatin. H2A variants represent the most numerous and diverse group among histone protein families. [...]
2018 - 10.3390/cancers10030059
Cancers, Vol. 10 (february 2018)  
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