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21 p, 2.7 MB Epigenome-wide gene-age interaction analysis reveals reversed effects of PRODH DNA methylation on survival between young and elderly early-stage NSCLC patients / Chen, C. (China International Cooperation Center for Environment and Human Health. Nanjing Medical University) ; Wei, Y. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Wei, Liangmin (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Chen, X. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Dong, X. (Department of Epidemiology and Biostatistics. School of Public Health. Southeast University) ; He, J. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Lin, L. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Zhu, Y. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Huang, H. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; You, D. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Lai, L. (Department of Biostatistics. Center for Global Health. School of Public Health. Nanjing Medical University) ; Shen, S. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Duan, W. (Department of Bioinformatics. School of Biomedical Engineering and Informatics. Nanjing Medical University) ; Su, L. (Department of Environmental Health. Harvard T.H. Chan School of Public Health) ; Shafer, A. (Harvard Medical School) ; Fleischer, T. (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Bjaanæs, Maria Moksnes (Department of Cancer Genetics. Institute for Cancer Research. Oslo University Hospital) ; Karlsson, A. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Planck, M. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Wang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Staaf, J. (Division of Oncology and Pathology. Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research. Lund University) ; Helland, Å. (Institute of Clinical Medicine. University of Oslo) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Zhang, R. (Department of Medical Oncology. Jinling Hospital. School of Medicine. Nanjing University) ; Chen, F. (Jiangsu Key Lab of Cancer Biomarkers. Prevention and Treatment. Cancer Center. Collaborative Innovation Center for Cancer Personalized Medicine. Nanjing Medical University) ; Christiani, David C (Harvard Medical School) ; Universitat Autònoma de Barcelona
DNA methylation changes during aging, but it remains unclear whether the effect of DNA methylation on lung cancer survival varies with age. Such an effect could decrease prediction accuracy and treatment efficacy. [...]
2020 - 10.18632/aging.103284
Aging (Albany NY), Vol. 12 Núm. 11 (15 2020) , p. 10642-10662  

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