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10 p, 933.0 KB |
Long-interval intracortical inhibition in primary motor cortex related to working memory in middle-aged adults
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Redondo-Camós, María (Institut Germans Trias i Pujol. Institut Guttmann) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ;
Alviarez-Schulze, Vanessa (Universitat de Barcelona) ;
Delgado-Gallén, Selma (Institut Germans Trias i Pujol. Institut Guttmann) ;
España-Irla, Goretti (Institut Germans Trias i Pujol. Institut Guttmann) ;
Solana-Sánchez, Javier (Institut Germans Trias i Pujol. Institut Guttmann) ;
Perellón-Alfonso, Ruben (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Albu, Sergiu (Institut Germans Trias i Pujol. Institut Guttmann) ;
Tormos, José M. (Institut Germans Trias i Pujol. Institut Guttmann) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Excitability of the primary motor cortex measured with TMS has been associated with cognitive dysfunctions in patient populations. However, only a few studies have explored this relationship in healthy adults, and even fewer have considered the role of biological sex. [...]
2022 -  10.3389/fpsyg.2022.998062
Frontiers in psychology, Vol. 13 (september 2022)
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10 p, 1.0 MB |
Local Prefrontal Cortex TMS-Induced Reactivity Is Related to Working Memory and Reasoning in Middle-Aged Adults
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Redondo-Camós, María (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Cattaneo, Gabriele (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Perellón-Alfonso, Ruben (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Alviarez-Schulze, Vanessa (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Morris, Timothy P. (Northeastern University) ;
Solana-Sánchez, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ;
España-Irla, Goretti (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Delgado-Gallén, Selma (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Pachón-García, Catherine (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Albu, Sergiu (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Zetterberg, Henrik (Hong Kong Center for Neurodegenerative Diseases) ;
Tormos, Josep M. (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Pascual Leone, Álvaro (Department of Neurology, Harvard Medical School) ;
Bartrés-Faz, David (Universitat Autònoma de Barcelona. Departament de Medicina)
The prefrontal cortex (PFC) plays a crucial role in cognition, particularly in executive functions. Cortical reactivity measured with Transcranial Magnetic Stimulation combined with Electroencephalography (TMS-EEG) is altered in pathological conditions, and it may also be a marker of cognitive status in middle-aged adults. [...]
2022 - 10.3389/fpsyg.2022.813444
Frontiers in psychology, Vol. 13 (february 2022)
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25 p, 4.0 MB |
Cortical responses to noninvasive perturbations enable individual brain fingerprinting
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Ozdemir, Recep A. (Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Interventional Cognitive Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA) ;
Tadayon, Ehsan (Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Interventional Cognitive Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA) ;
Boucher, Pierre (Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Interventional Cognitive Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA) ;
Sun, Haoqi (Harvard Medical School) ;
Momi, Davide (Department of Neuroscience, Imaging and Clinical Sciences, University of Chieti-PescarA) ;
Ganglberger, Wolfgang (Harvard Medical School) ;
Westover, M. Brandon (Harvard Medical School) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Santarnecchi, Emiliano (Department of Medicine, Surgery and Neuroscience, University of Siena, Italy) ;
Shafi, Mouhsin M. (Berenson-Allen Center for Noninvasive Brain Stimulation, Division of Interventional Cognitive Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA)
In recent years, it has become increasingly apparent that characterizing individual brain structure, connectivity and dynamics is essential for understanding brain function in health and disease. However, the majority of neuroimaging and brain stimulation research has characterized human brain function by averaging measurements from groups of subjects and providing population-level inferences. [...]
2021 - 10.1016/j.brs.2021.02.005
Brain stimulation, Vol. 14 (february 2021) , p. 391-403
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15 p, 1.4 MB |
Corticomotor Plasticity Predicts Clinical Efficacy of Combined Neuromodulation and Cognitive Training in Alzheimer's Disease
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Brem, Anna-Katharine (Beth Israel Deaconess Medical Center) ;
Di Iorio, Riccardo (Polyclinic A. Gemelli Foundation - IRCCS, Rome) ;
Fried, Peter J. (Beth Israel Deaconess Medical Center) ;
Oliveira-Maia, Albino J. (Champalimaud Centre for the Unknown, Lisbon) ;
Marra, Camillo (Polyclinic A. Gemelli Foundation - IRCCS, Rome) ;
Profice, Paolo (Polyclinic A. Gemelli Foundation - IRCCS, Rome) ;
Quaranta, Davide (Polyclinic A. Gemelli Foundation - IRCCS, Rome) ;
Schilberg, Lukas (Beth Israel Deaconess Medical Center) ;
Atkinson, Natasha J. (Beth Israel Deaconess Medical Center) ;
Seligson, Erica E. (Beth Israel Deaconess Medical Center) ;
Rossini, Paolo Maria (IRCCS San Raffaele, Rome) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
To investigate the efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training for treatment of cognitive symptoms in patients with Alzheimer's disease (AD). A secondary objective was to analyze associations between brain plasticity and cognitive effects of treatment. [...]
2020 - 10.3389/fnagi.2020.00200
Frontiers in aging neuroscience, Vol. 12 (july 2020)
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14 p, 2.2 MB |
Continuous Theta-Burst Stimulation in Children With High-Functioning Autism Spectrum Disorder and Typically Developing Children
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Jannati, Ali (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Block, Gabrielle (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Ryan, Mary A. (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Kaye, Harper L. (Harvard Medical School) ;
Kayarian, Fae B. (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Bashir, Shahid (Neuroscience Center, King Fahad Specialist Hospital Dammam) ;
Oberman, Lindsay M. (Neuroplasticity and Autism Spectrum Disorder Program, Department of Psychiatry and Human Behavior, E. P. Bradley Hospital, Warren Alpert Medical School, Brown University) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Rotenberg, Alexander (Berenson-Allen Center for Noninvasive Brain Stimulation and Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School) ;
Universitat Autònoma de Barcelona
Objectives : A neurophysiologic biomarker for autism spectrum disorder (ASD) is highly desirable and can improve diagnosis, monitoring, and assessment of therapeutic response among children with ASD. [...]
2020 - 10.3389/fnint.2020.00013
Frontiers in Integrative Neuroscience, Vol. 14 (march 2020)
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14 p, 2.1 MB |
Differential tDCS and tACS Effects on Working Memory-Related Neural Activity and Resting-State Connectivity
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Abellaneda-Pérez, Kilian (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Vaqué-Alcázar, Lídia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Perellón-Alfonso, Ruben (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Bargalló, Núria (Hospital Clínic i Provincial de Barcelona) ;
Kuo, Min-Fang (Leibniz Research Centre for Working Environment and Human Factors) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Nitsche, Michael A. (Department of Neurology, University Medical Hospital Bergmannsheil) ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Transcranial direct and alternating current stimulation (tDCS and tACS, respectively) entail capability to modulate human brain dynamics and cognition. However, the comparability of these approaches at the level of large-scale functional networks has not been thoroughly investigated. [...]
2020 - 10.3389/fnins.2019.01440
Frontiers in Neuroscience, Vol. 13 (january 2020)
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12 p, 7.2 MB |
Reduction of intratumoral brain perfusion by noninvasive transcranial electrical stimulation
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Sprugnoli, G. (Brain Investigation and Neuromodulation Laboratory. Department of Medicine. Surgery and Neuroscience. Unit of Neurology and Clinical Neurophysiology. Siena Medical School) ;
Monti, L. (Unit of Neuroimaging and Neurointervention. "Santa Maria Alle Scotte" Medical Center) ;
Lippa, L. (Unit of Neurosurgery. "Santa Maria Alle Scotte" Medical Center) ;
Neri, F. (Brain Investigation and Neuromodulation Laboratory. Department of Medicine. Surgery and Neuroscience. Unit of Neurology and Clinical Neurophysiology. Siena Medical School) ;
Mencarelli, L. (Brain Investigation and Neuromodulation Laboratory. Department of Medicine. Surgery and Neuroscience. Unit of Neurology and Clinical Neurophysiology. Siena Medical School) ;
Ruffini, G. (Neuroelectrics) ;
Salvador, R. (Neuroelectrics) ;
Oliveri, G. (Unit of Neurosurgery. "Santa Maria Alle Scotte" Medical Center) ;
Batani, B. (Unit of Neurosurgery. "Santa Maria Alle Scotte" Medical Center) ;
Momi, Davide (Brain Investigation and Neuromodulation Laboratory. Department of Medicine. Surgery and Neuroscience. Unit of Neurology and Clinical Neurophysiology. Siena Medical School) ;
Cerase, A. (Unit of Neuroimaging and Neurointervention. "Santa Maria Alle Scotte" Medical Center) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Rossi, A. (Department of Medicine. Surgery and Neuroscience. Human Physiology Section. Siena Medical School) ;
Rossi, S. (Department of Medicine. Surgery and Neuroscience. Human Physiology Section. Siena Medical School) ;
Santarnecchi, E. (Berenson-Allen Center for Noninvasive Brain Stimulation. Beth Israel Medical Center. Harvard Medical School) ;
Universitat Autònoma de Barcelona
Malignant brain neoplasms have a poor prognosis despite aggressive treatments. Animal models and evidence from human bodily tumors reveal that sustained reduction in tumor perfusion via electrical stimulation promotes tumor necrosis, therefore possibly representing a therapeutic option for patients with brain tumors. [...]
2019 - 10.1126/sciadv.aau9309
Science advances, Vol. 5 Núm. 8 (14 2019) , p. eaau9309
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16 p, 1.3 MB |
Test-retest reliability of the effects of continuous theta-burst stimulation
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Jannati, Ali (Berenson-Allen Center for Noninvasive Brain Stimulation. Division of Cognitive Neurology. Department of Neurology. Harvard Medical School) ;
Fried, P. J. (Berenson-Allen Center for Noninvasive Brain Stimulation. Division of Cognitive Neurology. Department of Neurology. Harvard Medical School) ;
Block, G. (School of Medicine. New York Medical College) ;
Oberman, L. M. (Department of Medical and Clinical Psychology. Uniformed Services University of Health Sciences) ;
Rotenberg, Alexander (Boston Children's Hospital (Boston, Estats Units d'Amèrica)) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Objectives: The utility of continuous theta-burst stimulation (cTBS) as index of cortical plasticity is limited by inadequate characterization of its test-retest reliability. We thus evaluated the reliability of cTBS aftereffects, and explored the roles of age and common single-nucleotide polymorphisms in the brain-derived neurotrophic factor (BDNF) and apolipoprotein E (APOE) genes. [...]
2019 - 10.3389/fnins.2019.00447
Frontiers in Neuroscience, Vol. 13 Núm. MAY (2019) , p. 447
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