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1.
14 p, 563.4 KB Clinical management of epidermal growth factor receptor mutation-positive non-small cell lung cancer patients after progression on previous epidermal growth factor receptor tyrosine kinase inhibitors : The necessity of repeated molecular analysis / González-Larriba, José Luis (Hospital Universitario Clínico San Carlos (Madrid)) ; Lázaro-Quintela, Martín (Complexo Hospitalario Universitario de Vigo) ; Cobo, Manuel (Hospital Regional Universitario de Málaga) ; Dómine, Manuel (Hospital Universitario Fundación Jiménez Díaz) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; García-Campelo, Rosario (Complejo Hospitalario Universitario de A Coruña) ; Universitat Autònoma de Barcelona
One of the most important advances in the treatment of non-small cell lung cancer (NSCLC) has been the identification of molecular alterations vulnerable to targeted inhibition, such as mutations in the epidermal growth factor receptor (EGFR) gene. [...]
2017 - 10.21037/tlcr.2017.10.03
Translational Lung Cancer Research, Vol. 6 (january 2017) , p. S21-S34  
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2.
11 p, 474.2 KB Phase 1/2 Study of the CD56-Targeting Antibody-Drug Conjugate Lorvotuzumab Mertansine (IMGN901) in Combination With Carboplatin/Etoposide in Small-Cell Lung Cancer Patients With Extensive-Stage Disease / Socinski, Mark A. (Univeristy of Pittsburgh Cancer Institute) ; Kaye, Frederic J. (University of Florida College of Medicine) ; Spigel, David R. (Sarah Cannon Research Institute) ; Kudrik, Fred J. (South Carolina Oncology Associates) ; Ponce, Santiago (Hospital 12 de Octubre (Madrid)) ; Ellis, Peter M. (Juravinski Cancer Centre) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Lorigan, Paul (University of Manchester/Christie NHS Foundation Trust) ; Gandhi, Leena (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; Gutierrez, Martin E. (Holy Cross Hospital) ; Nepert, Dale (Clinical Development. ImmunoGen Inc) ; Corral, Jesus (Hospital 12 de Octubre (Madrid)) ; Ares, Luis Paz (Hospital 12 de Octubre (Madrid)) ; Universitat Autònoma de Barcelona
Lorvotuzumab mertansine (LM, IMGN901) is a CD56-targeting antibody-drug conjugate developed for tumor-selective delivery of the cytotoxic maytansinoid DM1. This phase 1/2 study evaluated the combination of LM with first-line carboplatin/etoposide chemotherapy in patients with extensive-disease small-cell lung cancer. [...]
2017 - 10.1016/j.cllc.2016.09.002
Clinical Lung Cancer, Vol. 18 Núm. 1 (january 2017) , p. 68-76.e2  
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3.
11 p, 639.3 KB Seroprevalence and immunological memory against SARS-CoV-2 in lung cancer patients : the SOLID study / Provencio, Mariano (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Rodríguez-Abreu, Delvys (Hospital Universitario Insular de Gran Canaria) ; Ortega Granados, Ana Laura (Hospital Universitario de Jaén) ; Serrano, Gloria (Hospital Universiario Infanta Leonor (Madrid)) ; Aguado, Carlos (Hospital Clínico San Carlos (Madrid)) ; Franco, Fernando (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Gutierrez, Vanesa (Hospital Universitario Regional de Málaga) ; López-Vivanco, Guillermo (Hospital Universitario Cruces (Barakaldo, País Basc)) ; Guirado Risueño, María (Hospital General Universitario de Elche) ; Benítez, Gretel (Hospital Universitario Insular de Gran Canaria) ; Estival, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Calvo, Virginia (Hospital Universitario Puerta de Hierro Majadahonda) ; Jiménez, Beatriz (Hospital Universitario HM Sanchinarro (Madrid)) ; Arasanz, Hugo (Complejo Hospitalario Navarra-Navarrabiomeed) ; Coves, Juan (Hospital Universitari Son LLàtzer (Palma de Mallorca, Balears)) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Massutí, Bartomeu (Hospital General Universitario de Alicante (Alacant, País Valencià)) ; Vázquez, Sergio (Hospital Universitario Lucus Augusti (Lugo)) ; Juan, Óscar (Hospital Universitario y Politécnico La Fe) ; Collazo-Lorduy, Ana (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Gozálvez, Clara L. (Hospital Universitari Sant Joan de Reus (Tarragona)) ; Barco, Edel D. (Hospital Clínico Universitario (Salamanca)) ; Rosero, Adriana (Hospital Universitario Infanta Cristina) ; Bosch-Barrera, J. (Institut Català d'Oncologia) ; Moreno, María A. (Hospital Universitario de Puerto Real (Cadis)) ; Mielgo-Rubio, X. (Hospital Universitario Fundación Alcorcón) ; Villa, J.C. (Hospital General Universitario Ciudad Real) ; López-Martin, A. (Hospital Universitario Severo Ochoa) ; Córdoba Ortega, Juan Felipe (Hospital Universitario Arnau de Vilanova) ; de Asís Aparisi, F. (Hospital General Universitario de Valencia) ; Zafra, M. (Hospital General Universitario Morales Meseguer (Múrcia)) ; Mosquera, J. (Complejo Hospitalario Universitario de A Coruña) ; Altozano, J.P. (Hospital Virgen de los Lirios) ; Nadal, E. (Institut Català d'Oncologia. Hospitalet de Llobregat) ; Catot, S. (Altaia. Xarxa Assistencial Universitaria Manresa) ; Balsalobre, J. (Hospital General Universitario Santa Lucia Cartagena) ; de Portugal, T. (Complejo Hospitalario de Zamora) ; Martín, P. (Hospital Clínic Universitari (València)) ; de Juan, S.C. (Laboratorio Central) ; Cobo, M. (Hospital Universitario Regional de Málaga) ; Universitat Autònoma de Barcelona
At present, we did not find any articles that studied seroprevalence and its persistence several months later in lung cancer patients in the setting of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. [...]
2022 - 10.21037/tlcr-21-504
Translational Lung Cancer Research, Vol. 11 Núm. 1 (january 2022) , p. 53-63  
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4.
12 p, 843.6 KB Association of hepatitis B virus infection status with outcomes of non-small cell lung cancer patients undergoing anti-PD-1/PD-L1 therapy / Zhang, Xuanye (Sun Yat-sen University Cancer Center) ; Tian, Dan (Guangdong Academy of Medical Sciences) ; Chen, Yue (The Eighth Affiliated Hospital of Sun Yat-sen University) ; Chen, Chen (Sun Yat-sen University Cancer Center) ; He, Li-Na (Sun Yat-sen University Cancer Center) ; Zhou, Yixin (Sun Yat-sen University Cancer Center) ; Li, Haifeng (Sun Yat-sen University Cancer Center) ; Lin, Zuan (Sun Yat-sen University Cancer Center) ; Chen, Tao (Sun Yat-sen University Cancer Center) ; Wang, Yuhong (Sun Yat-sen University Cancer Center) ; Russo, Alessandro (A.O. Papardo) ; Nadal, Ernest (Hospital Universitari de Bellvitge) ; Passiglia, Francesco (S. Luigi Gonzaga Hospital) ; Soo, Ross Andrew (National University Health System) ; Watanabe, Satoshi (Niigata University Graduate School of Medical and Dental Sciences) ; Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Oh, In-Jae (Hwasun Hospital) ; Fu, Sha (Sun Yat-sen University) ; Hong, Shaodong (Sun Yat-sen University Cancer Center) ; Zhang, Li (Sun Yat-sen University Cancer Center) ; Universitat Autònoma de Barcelona
The aim of this study was to evaluate the safety and survival outcomes of anti-programmed cell death (PD)-1/programmed cell death-ligand 1 (PD-L1) monotherapy in patients with advanced non-small cell lung cancer (NSCLC) and different hepatitis B virus (HBV) infection status. [...]
2021 - 10.21037/tlcr-21-455
Translational Lung Cancer Research, Vol. 10 (july 2021) , p. 3191-3202  
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5.
12 p, 608.0 KB Characteristics and Management of Patients with Refractory or Unexplained Chronic Cough in Outpatient Hospital Clinics in Spain : A Retrospective Multicenter Study / Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Dávila, Ignacio (Universidad de Salamanca) ; Puente, Luis (Hospital General Universitario Gregorio Marañón) ; Quirce Gancedo, Santiago (Hospital Universitario La Paz (Madrid)) ; Arismendi, Ebymar (Hospital Clínic i Provincial de Barcelona) ; Díaz Palacios, Miguel (Hospital Universitari i Politècnic La Fe (València)) ; Pereira-Vega, Antonio (Hospital Juan Ramón Jiménez (Huelva)) ; De Diego, Alfredo (Hospital Universitari i Politècnic La Fe (València)) ; Rodriguez Hermosa, Juan Luis (Universidad Complutense de Madrid) ; Cea-Calvo, Luis (MSD España) ; Sánchez Jareño, Marta (MSD España) ; López Cotarelo, Pilar (MSD España) ; Universitat Autònoma de Barcelona
Purpose: Chronic cough (cough that persists for ≥ 8 weeks) can cause a range of physical symptoms and psychosocial effects that significantly impair patients' quality of life. Refractory chronic cough (RCC) and unexplained chronic cough (UCC) are challenging to diagnose and manage, with substantial economic implications for healthcare systems. [...]
Springer New York, 2023 - 10.1007/s00408-023-00620-y
Lung  
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6.
15 p, 607.8 KB PD-L1 testing and clinical management of newly diagnosed metastatic non-small cell lung cancer in Spain : MOREL study / Rubio-Viqueira, Belen (Department of Medical Oncology. Quirónsalud Madrid Hospital. Pozuelo de Alarcón) ; Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ; Lázaro, Martín (Hospital Álvaro Cunqueiro (Vigo)) ; Estévez, Sergio Vázquez (Hospital Universitario Lucus Augusti (Lugo)) ; Córdoba Ortega, Juan Felipe (Hospital Arnau de Vilanova (Lleida, Catalunya)) ; Maiques, Inmaculada Maestu (Hospital Universitari Doctor Peset (València)) ; González, Jorge García (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ; Cordellat, Ana Blasco (Hospital General Universitario de Valencia) ; Valdivia-Bautista, Javier (Hospital Universitario Virgen de las Nieves (Granada)) ; Arenas, Carmen González (Department of Medical Oncology. Msd) ; Sánchez Torres, José Miguel (Hospital Universitario de la Princesa (Madrid))
Aim: To describe the clinical management and PD-L1 testing of patients with newly diagnosed stage IV non-small cell lung cancer (NSCLC) without driver mutations in Spain. Methods: Multicenter, retrospective study. [...]
2021 - 10.2217/lmt-2021-0008
Lung Cancer Management, Vol. 10 Núm. 4 (december 2021) , p. LMT53  
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