UAB Digital Repository of Documents 69 records found  beginprevious60 - 69  jump to record: Search took 0.01 seconds. 
60.
15 p, 1.7 MB Fast sequence evolution of Hox and Hox-derived genes in the genus Drosophila / Casillas Viladerrams, Sònia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Negre de Bofarull, Bárbara (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Barbadilla Prados, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Ruiz, Alfredo, (Ruiz Panadero) (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Background: It is expected that genes that are expressed early in development and have a complex expression pattern are under strong purifying selection and thus evolve slowly. Hox genes fulfill these criteria and thus, should have a low evolutionary rate. [...]
2006 - 10.1186/1471-2148-6-106
BMC evolutionary biology, Vol. 6, N. 106 (December 2006) , p. 1-15  
61.
15 p, 522.3 KB Thermal evolution of gene expression profiles in Drosophila subobscura / Laayouni, Hafid (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; García-Franco, Francisco (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Chávez Sandoval, Blanca Estela (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Trotta, Vincenzo (Università di Bologna (Itàlia). Dipartimento di Biologia Evoluzionistica Sperimentale) ; Beltran i Agulló, Sergi (Universitat de Barcelona. Departament de Genètica) ; Santos, Mauro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Corominas, Montserrat (Universitat de Barcelona. Departament de Genètica)
Background: Despite its pervasiveness, the genetic basis of adaptation resulting in variation directly or indirectly related to temperature (climatic) gradients is poorly understood. By using 3-fold replicated laboratory thermal stocks covering much of the physiologically tolerable temperature range for the temperate (i. [...]
2007 - 10.1186/1471-2148-7-42
BMC evolutionary biology, Vol. 7, N. 42 (March 2007) , p. 1-15  
62.
15 p, 546.4 KB Chromosomal instability in Afrotheria : fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies / Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Robinson, Terence J. (Universita' degli Studi di Pavia. Dipartimento di Genetica e Microbiologia (Itàlia))
Background: Extant placental mammals are divided into four major clades (Laurasiatheria, Supraprimates, Xenarthra and Afrotheria). Given that Afrotheria is generally thought to root the eutherian tree in phylogenetic analysis of large nuclear gene data sets, the study of the organization of the genomes of afrotherian species provides new insights into the dynamics of mammalian chromosomal evolution. [...]
2007 - 10.1186/1471-2148-7-199
BMC evolutionary biology, Vol. 7, N. 199 (October 2007) , p. 1-15  
63.
12 p, 535.3 KB Mutation patterns of mtDNA : empirical inferences for the coding region / Pereira dos Santos, Cristina Maria (University of the Azores. Center for Research in Natural Resources) ; Montiel, Rafael (University of the Azores. Center for Research in Natural Resources) ; Arruda, Adriana (University of the Azores. Center for Research in Natural Resources) ; Álvarez, Luis (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Aluja París, Maria Pilar (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Lima, Manuela (University of the Azores. Center for Research in Natural Resources)
Background: Human mitochondrial DNA (mtDNA) has been extensively used in population and evolutionary genetics studies. Thus, a valid estimate of human mtDNA evolutionary rate is important in many research fields. [...]
2008 - 10.1186/1471-2148-8-167
BMC evolutionary biology, Vol. 8, N. 167 (June 2008) , p. 1-12
2 documents
64.
12 p, 404.5 KB Genetic hitchhiking can promote the initial spread of strong altruism / Santos, Mauro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Szathmáry, Eörs (Collegium Budapest. Institute for Advanced Study (Hongria))
Background: The evolutionary origin of strong altruism (where the altruist pays an absolute cost in terms of fitness) towards non-kin has never been satisfactorily explained since no mechanism (except genetic drift) seems to be able to overcome the fitness disadvantage of the individual who practiced altruism in the first place. [...]
2008 - 10.1186/1471-2148-8-281
BMC evolutionary biology, Vol. 8, N. 281 (October 2008) , p. 1-12  
65.
13 p, 386.5 KB Distribution of the transposable elements bilbo and gypsy in original and colonizing populations of Drosophila subobscura / García Guerreiro, María Pilar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Chávez Sandoval, Blanca Estela (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Balanyà i Maymó, Joan (Universitat de Barcelona. Departament de Genètica) ; Serra i Camó, Lluís (Universitat de Barcelona. Departament de Genètica) ; Fontdevila, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Background: Transposable elements (TEs) constitute a substantial amount of all eukaryotic genomes. They induce an important proportion of deleterious mutations by insertion into genes or gene regulatory regions. [...]
2008 - 10.1186/1471-2148-8-234
BMC evolutionary biology, Vol. 8, N. 234 (August 2008) , p. 1-13  
66.
12 p, 2.4 MB Osvaldo and Isis retrotransposons as markers of the Drosophila buzzatii colonization in Australia / Fontdevila, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; García Guerreiro, María Pilar (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Background: Transposable elements (TEs) constitute an important source of genetic variability owing to their jumping and regulatory properties, and are considered to drive species evolution. Several factors that are able to induce TE transposition in genomes have been documented (for example environmental stress and inter- and intra-specific crosses) but in many instances the reasons for TE mobilisation have yet to be elucidated. [...]
2011 - 10.1186/1471-2148-11-111
BMC evolutionary biology, Vol. 11, N. 111 (April 2011) , p. 1-12  
67.
7 p, 1.0 MB Variational modularity at the cell level : insights from the sperm head of the house mouse / Medarde González, Núria Estel (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Muñoz Muñoz, Francesc (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; López Fuster, María José (Universitat de Barcelona. Departament de Biologia Animal) ; Ventura Queija, Jacinto (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Background: Modularity is an important feature in the evolvability of organisms, since it allows the occurrence of complex adaptations at every single level of biological systems. While at the cellular level the modular organization of molecular interactions has been analyzed in detail, the phenotypic modularity (or variational modularity) of cell shape remains unexplored. [...]
2013 - 10.1186/1471-2148-13-179
BMC evolutionary biology, Vol. 13, N. 179 (September, 2013)  
68.
10 p, 323.1 KB Optimization of immunomagnetic separation for cord blood-derived hematopoietic stem cells / Kekarainen, Tuija (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Mannelin, Sirkka (Finnish Red Cross Blood Service (Helsinki, Finlàndia)) ; Laine, Jarmo (Finnish Red Cross Blood Service (Helsinki, Finlàndia)) ; Jaatinen, Taina (Finnish Red Cross Blood Service (Helsinki, Finlàndia))
Background: There is a growing interest in cord blood as a source of primitive stem cells with the capacity for multilineage differentiation. Pure cell fractions are needed for the characterization and in vitro expansion of stem cells as well as for their use in preclinical research. [...]
2006 - 10.1186/1471-2121-7-30
BMC Cell biology, Vol. 7, N. 30 (August 2006) , p. 1-10  
69.
14 p, 1.9 MB Assessing the structural conservation of protein pockets to study functional and allosteric sites: implications for drug discovery / Panjkovich, Alejandro (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Daura i Ribera, Xavier (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Background: With the classical, active-site oriented drug-development approach reaching its limits, protein ligand-binding sites in general and allosteric sites in particular are increasingly attracting the interest of medicinal chemists in the search for new types of targets and strategies to drug development. [...]
2010 - 10.1186/1472-6807-10-9
BMC Structural biology, Vol. 10, Núm. 9 (March 2010) , p. 9-9  

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