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1.
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17 p, 3.3 MB |
Impact of 1-Year Supplementation with High-Rich Docosahexaenoic Acid (DHA) on Clinical Variables and Inflammatory Biomarkers in Pediatric Cystic Fibrosis : A Randomized Double-Blind Controlled Trial
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Ayats-Vidal, Roser (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bosque, Montserrat (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cordobilla, Begoña (Universitat de Barcelona) ;
Asensio-De la Cruz, Oscar (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
García-González, Miguel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Loureda-Pérez, Susana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Fernández-López, Elena (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Robert-Barriocanal, Eva (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Valiente-Planas, Andrea (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Domingo, Joan Carles (Universitat de Barcelona) ;
Universitat Autònoma de Barcelona
A randomized, double-blind, and placebo-controlled study was conducted to assess the effect of dietary supplementation with high-rich docosahexaenoic acid (DHA) (Tridocosahexanoin-AOX ® 70%) at 50 mg/kg/day in pediatric patients with cystic fibrosis (CF) as compared with placebo. [...]
2024 -  10.3390/nu16070970
Nutrients, Vol. 16 (march 2024)
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2.
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12 p, 333.4 KB |
Detailed comparison between organic and conventional milk from Holstein-Friesian dairy herds in Italy
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Manuelian, Carmen L (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Vigolo, V. (Università degli Studi di Padova) ;
Burbi, S. (Coventry University) ;
Righi, F. (Università degli Studi di Parma) ;
Simoni, M. (Università degli Studi di Parma) ;
De Marchi, M. (Università degli Studi di Padova)
Several studies have reported gross composition differences between organic and conventional milk; however, most studies have not considered other factors such as breed and diet ingredients, which are known to influence milk composition. [...]
2022 - 10.3168/jds.2021-21465
Journal of dairy science, Vol. 105 Núm. 7 (2022) , p. 5561-5572
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3.
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16 p, 965.4 KB |
Changes of Erythrocyte Fatty Acids after Supplementation with Highly Concentrated Docosahexaenoic Acid (DHA) in Pediatric Cystic Fibrosis : A Randomized Double-Blind Controlled Trial
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Ayats-Vidal, Roser (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bosque, Montserrat (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cordobilla, Begoña (Universitat de Barcelona) ;
Asensio-De la Cruz, Oscar (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
García-González, Miguel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
López-Rico, Irene (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Domingo, Joan Carles (Universitat de Barcelona) ;
Universitat Autònoma de Barcelona
We characterized the fatty acid profiles in the erythrocyte membrane of pediatric patients with cystic fibrosis (CF) receiving highly concentrated docosahexaenoic acid (DHA) supplementation (Tridocosahexanoin-AOX ® 70%) at 50 mg/kg/day (n = 11) or matching placebo (n = 11) for 12 months. [...]
2023 - 10.3390/jcm12113704
Journal of clinical medicine, Vol. 12 (may 2023)
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4.
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25 p, 4.7 MB |
The Impact of Fiber Source on Digestive Function, Fecal Microbiota, and Immune Response in Adult Dogs
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Montserrat-Malagarriga, Miquel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Castillejos, Lorena (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Salas-Mani, Anna (Affinity Pet Care (Hospitalet de Llobregat)) ;
Torre, Celina (Affinity Pet Care (Hospitalet de Llobregat)) ;
Martín Orúe, Susana M (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Dietary fiber has been widely recognized to have a profound impact on gut microbiota and health. However, the ideal fiber intake in dogs still needs to be determined. Fiber is not a single kind of molecule, but a plethora of compounds that are diverse in chemical composition and properties, including solubility, viscosity, and fermentability. [...]
2024 - 10.3390/ani14020196
Animals, Vol. 14 (january 2024)
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5.
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25 p, 4.8 MB |
Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities
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Kakularam, Kumar R. (Charité-Universitätsmedizin Berlin. Department of Biochemistry) ;
Canyelles-Niño, Miquel (Universitat Autònoma de Barcelona. Departament de Química) ;
Chen, Xin (Charité-Universitätsmedizin Berlin. Department of Biochemistry) ;
Lluch López, Josep Maria (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
González-Lafont, Àngels (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Kuhn, Hartmut (Charité-Universitätsmedizin Berlin. Department of Biochemistry)
The arachidonic acid lipoxygenase 15B (ALOX15B) orthologs of men and mice form different reaction products when arachidonic acid is used as the substrate. Tyr603Asp+His604Val double mutation in mouse arachidonic acid lipoxygenase 15b humanized the product pattern and an inverse mutagenesis strategy murinized the specificity of the human enzyme. [...]
2023 - 10.3390/ijms241210046
International journal of molecular sciences, Vol. 24, Issue 12 (June 2023) , art. 10046
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6.
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9 p, 298.3 KB |
Comparison of chemical composition of organic and conventional Italian cheeses from parallel production
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Manuelian, Carmen L (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ;
Pozza, M. (University of Padova. Department of Agronomy, Food, Natural resources, Animals and Environment) ;
Franzoi, Marco (University of Padova. Department of Agronomy, Food, Natural resources, Animals and Environment) ;
Righi, Federico (Università degli Studi di Parma. Department of Veterinary Science) ;
Schmutz, U. (Coventry University. Centre for Agroecology, Water and Resilience) ;
De Marchi, Massimo (University of Padova. Department of Agronomy, Food, Natural resources, Animals and Environment)
Although there are several studies comparing organic and conventional milk characteristics, very few focused on dairy processed products such as cheese. Thus, this study aimed for a detailed controlled examination of gross composition, minerals, and the fatty acid profile of organic (ORG) and conventional (CON) Italian cheeses from parallel production. [...]
2023 - 10.3168/jds.2022-22730
Journal of dairy science, Vol. 106 Núm. 10 (2023) , p. 6646-6654
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7.
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6.8 MB |
Efecto de la suplementación con ácido docosahexaenoico (DHA) en pacientes pediátricos con fibrosis quística : Ensayo clínico aleatorizado controlado con placebo
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Ayats-Vidal, Roser ;
Bosque, Montserrat, dir. ;
Domingo i Pedrol, Joan Carles, dir. ;
Blanch Torra, Lluís, dir.
Introducció: En els pacients amb fibrosi quística (FQ) s'ha descrit una alteració al metabolisme dels àcids grassos (AG) caracteritzada per un descens dels nivells d'àcid docosahexaenoic (DHA), associat a un augment de la inflamació basal. [...]
Introducción: En los pacientes con fibrosis quística (FQ) se ha descrito una alteración en el metabolismo de los ácidos grasos (AG) caracterizada por un descenso de los niveles de ácido docosahexaenoico (DHA), asociado a un aumento de la inflamación basal. [...]
Background: Cystic fibrosis (CF) patients have an alteration in fatty acid (FA) metabolism, characterized by a low docosahexaenoic acid (DHA), associated with an increase in basal inflammation. Supplementing these patients with DHA could have an anti-inflammatory effect for which there is currently not enough evidence to recommend it. [...]
2023
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7 p, 330.2 KB |
Dietary Fat Patterns and Outcomes in Acute Pancreatitis in Spain
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García-Rayado, G. (Instituto de Investigaciones Sanitarias de Aragón (IIS Aragón)) ;
Varela-Moreiras, G. (Universidad CEU San Pablo) ;
Lanas, Á. (Instituto de Investigaciones Sanitarias de Aragón (IIS Aragón)) ;
Ferrández, Á. (Instituto de Investigaciones Sanitarias de Aragón (IIS Aragón)) ;
Balza-Lareu, N. (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Cervera, J.I. (Hospital Clínico Universitario) ;
Bodenlle-Bello, M.P. (Hospital Meixoeiro) ;
Argüelles-Arias, A.M. (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Latorre, P. (Hospital Universitari Doctor Peset (València)) ;
Udaondo-Cascante, M.A. (Hospital Clínico Universitario) ;
Soria-de-la-Cruz, M.J. (Hospital Universitario Puerta del Mar (Cadis, Andalusia)) ;
Lariño-Noia, J. (Complejo Hospitalario Universitario de Santiago de Compostela) ;
García-Figueiras, R. (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Gil-García-Ollauri, C. (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Ituarte-Uriarte, R. (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Rosales-Alexander, C.L. (Hospital Universitari de Girona Doctor Josep Trueta) ;
Soriano, J. (Hospital Universitari de Girona Doctor Josep Trueta) ;
Rodríguez-Peláez, M. (Hospital Universitario Central de Asturias) ;
Mesa-Álvarez, A. (Hospital Universitario Central de Asturias) ;
Oblitas, Elida (Institut d'Investigació Biomèdica Sant Pau) ;
Menso, Maria (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Bertoletti, Federico (Institut d'Investigació Biomèdica Sant Pau) ;
Rodríguez-Prada, J.I. (Hospital Xeral) ;
Guzmán-Suárez, S. (Hospital Xeral) ;
Closa, D. (Institut d'Investigacions Biomèdiques de Barcelona (IIBB-CSIC)) ;
de-Madaria, E. (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Universitat Autònoma de Barcelona
Evidence from basic and clinical studies suggests that unsaturated fatty acids (UFAs) might be relevant mediators of the development of complications in acute pancreatitis (AP). The aim of this study was to analyze outcomes in patients with AP from regions in Spain with different patterns of dietary fat intake. [...]
2020 - 10.3389/fmed.2020.00126
Frontiers in Medicine, Vol. 7 (september 2020) , p. 126
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10.
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11 p, 2.5 MB |
Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis
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Kandel, Prasanna (Department of Biochemistry and Molecular Biomedicine. Institute of Biomedicine. University of Barcelona) ;
Semerci, Fatih (Universitat de Barcelona. Institut de Biomedicina. Departament de Bioquímica i Biomedicina Molecular) ;
Mishra, Rachana (Jan and Dan Duncan Neurological Research Institute. Texas Children's Hospital) ;
Choi, Willian (Medical Scientist Training Program. Baylor College of Medicine) ;
Bajic, Aleksandar (Department of Molecular and Human Genetics. Baylor College of Medicine) ;
Baluya, Dodge (Department of Interventional Radiology. University of Texas MD Anderson Cancer Center) ;
Ma, Li Hua (NMR and Drug Metabolism Advanced Technology Cores. Baylor College of Medicine) ;
Chen, Kevin (Department of Biosciences. Rice University) ;
Cao, Austin C. (Department of Chemistry. Rice University) ;
Phongmekhin, Tipwarin (Department of Biosciences. Rice University) ;
Matinyan, Nick (Verna and Marrs McLean Department of Biochemistry and Molecular Biology. Baylor College of Medicine) ;
Jimenez-Panizo, Alba (Universitat de Barcelona. Institut de Biomedicina. Departament de Bioquímica i Biomedicina Molecular) ;
Chamakuri, Srinivas (Department of Pathology and Immunology. Baylor College of Medicine) ;
Raji, Idris O. (Department of Pharmacology & Chemical Biology. Baylor College of Medicine) ;
Chang, Lyra (Department of Pharmacology & Chemical Biology. Baylor College of Medicine) ;
Fuentes-Prior, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
MacKenzie, Kevin R. (Department of Molecular and Cellular Biology. Baylor College of Medicine) ;
Benn, Caroline L. (Pfizer Regenerative Medicine) ;
Estebanez-Perpiña, Eva (Department of Biochemistry and Molecular Biomedicine. Institute of Biomedicine. University of Barcelona) ;
Venken, Koen (Verna and Marrs McLean Department of Biochemistry and Molecular Biology. Baylor College of Medicine) ;
Moore, David D. (Department of Molecular and Cellular Biology. Baylor College of Medicine) ;
Young, Damian W. (Center for Drug Discovery. Baylor College of Medicine) ;
Maletic-Savatic, Mirjana (Department of Neuroscience. Baylor College of Medicine)
Neural stem cells, the source of newborn neurons in the adult hippocampus, are intimately involved in learning and memory, mood, and stress response. Despite considerable progress in understanding the biology of neural stem cells and neurogenesis, regulating the neural stem cell population precisely has remained elusive because we have lacked the specific targets to stimulate their proliferation and neurogenesis. [...]
2022 - 10.1073/pnas.2023784119
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119 Núm. 13 (March 2022) , p. e2023784119
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