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30.
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8 p, 1.1 MB |
Serum circular RNAs act as blood-based biomarkers for hypertrophic obstructive cardiomyopathy
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Sonnenschein, Kristina (Hannover Medical School. Department of Cardiology and Angiology) ;
Wilczek, Adriana Luisa (Institute of Molecular and Translational Therapeutic Strategies (IMTTS). Hannover Medical School) ;
Gonzalo Calvo, David de (Institut d'Investigació Biomèdica Sant Pau) ;
Pfanne, Angelika (Institute of Molecular and Translational Therapeutic Strategies (IMTTS). Hannover Medical School) ;
Derda, Anselm Arthur (Hannover Medical School. Department of Cardiology and Angiology) ;
Zwadlo, Carolin (Hannover Medical School. Department of Cardiology and Angiology) ;
Bavendiek, Udo (Hannover Medical School. Department of Cardiology and Angiology) ;
Bauersachs, Johann (REBIRTH Center of Translational Regenerative Medicine. Hannover Medical School) ;
Fiedler, Jan (Institute of Molecular and Translational Therapeutic Strategies (IMTTS). Hannover Medical School) ;
Thum, Thomas (REBIRTH Center of Translational Regenerative Medicine. Hannover Medical School)
Hypertrophic cardiomyopathy (HCM) is one of the most common hereditary heart diseases and is associated with a high risk of sudden cardiac death. HCM is characterized by pronounced hypertrophy of cardiomyocytes, fiber disarray and development of fibrosis and can be divided into a non-obstructive (HNCM) and obstructive form (HOCM) therefore requiring personalized therapeutic therapies. [...]
2019 -  10.1038/s41598-019-56617-2
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 20350
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31.
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11 p, 1.9 MB |
Migrated T lymphocytes into malignant pleural effusions : an indicator of good prognosis in lung adenocarcinoma patients
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Nieto Sáchica, Juan Camilo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Zamora, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Porcel, José M. (Hospital Universitari Arnau de Vilanova) ;
Mulet Gual, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Pajares Ruiz, Virginia (Institut d'Investigació Biomèdica Sant Pau) ;
Muñoz-Fernandez, Ana M. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Calvo, Nuria (Institut d'Investigació Biomèdica Sant Pau) ;
Espinosa, Iñigo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Pascual-García, Mónica (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Bielsa, Silvia (Hospital Universitari Arnau de Vilanova) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
The presence of leukocyte subpopulations in malignant pleural effusions (MPEs) can have a different impact on tumor cell proliferation and vascular leakiness, their analysis can help to understand the metastatic microenvironment. [...]
2019 - 10.1038/s41598-018-35840-3
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 2996
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32.
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10 p, 1.6 MB |
Neuroprotection mediated by cystatin C-loaded extracellular vesicles
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Pérez-González, Rocío (Institut d'Investigació Biomèdica Sant Pau) ;
Sahoo, Susmita (Icahn School of Medicine at Mount Sinai) ;
Gauthier, Sebastien A. (Nathan S. Kline Institute) ;
Kim, Yohan (NYU Langone Medical Center) ;
Li, Meihua (Nathan S. Kline Institute) ;
Kumar, Asok (Nathan S. Kline Institute) ;
Pawlik, Monika (Nathan S. Kline Institute) ;
Benussi, Luisa (IRCCS Istituto Centro San Giovanni di Dio-Fatebenefratelli) ;
Ghidoni, Roberta (IRCCS Istituto Centro San Giovanni di Dio-Fatebenefratelli) ;
Levy, Efrat (Neuroscience Institute) ;
Universitat Autònoma de Barcelona
Cystatin C (CysC) is implicated in neuroprotection and repair in the nervous system in response to diverse neurotoxic conditions. In addition to being secreted from cells in a soluble form, CysC is released by cells in association with extracellular vesicles (EVs), including exosomes. [...]
2019 - 10.1038/s41598-019-47524-7
Scientific reports, Vol. 9 Núm. 1 (31 2019) , p. 11104
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33.
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10 p, 1.5 MB |
Prediction of protein subplastid localization and origin with PlastoGram
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Sidorczuk, Katarzyna (University of Wrocław) ;
Gagat, Przemysław (University of Wrocław) ;
Kała, Jakub (Warsaw University of Technology) ;
Nielsen, Henrik (Technical University of Denmark. Department of Health Technology) ;
Pietluch, Filip (University of Wrocław) ;
Mackiewicz, Paweł (University of Wrocław) ;
Burdukiewicz, Michał (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Due to their complex history, plastids possess proteins encoded in the nuclear and plastid genome. Moreover, these proteins localize to various subplastid compartments. Since protein localization is associated with its function, prediction of subplastid localization is one of the most important steps in plastid protein annotation, providing insight into their potential function. [...]
2023 - 10.1038/s41598-023-35296-0
Scientific reports, Vol. 13 (May 2023) , art. 8365
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34.
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14 p, 3.6 MB |
Unprecedented recent regional increase in organic carbon and lithogenic fluxes in high altitude Pyrenean lakes
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Vicente de Vera García, Alejandra (Pyrenean Institute of Ecology) ;
Mata-Campo, María Pilar (Geological and Mining Institute of Spain) ;
Pla-Rabes, Sergi (Centre de Recerca Ecològica i d'Aplicacions Forestals) ;
Vicente, Eduardo (Universidad de Valencia. Instituto Cavanilles) ;
Prego, Ricardo (Marine Research Institute. Department of Oceanography) ;
Frugone-Álvarez, Matías (Núcleo Milenio UPWELL) ;
Polanco-Martínez, Josué (Basque Centre for Climate Change-BC3) ;
Galofré, Marcel (Pyrenean Institute of Ecology) ;
Valero-Garcés, Blas Lorenzo (Pyrenean Institute of Ecology) ;
Universitat Autònoma de Barcelona
We have conducted a monitoring survey and paleolimnological study of a W-E transect of six high altitude lakes (1870-2630 m asl) in the western and central Pyrenees (Spain) to evaluate the regional response to current global change in high altitude Mediterranean mountains. [...]
2023 - 10.1038/s41598-023-35233-1
Scientific reports, Vol. 13 (May 2023) , art. 8586
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35.
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10 p, 2.8 MB |
A de novo evolved domain improves the cadmium detoxification capacity of limpet metallothioneins
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García-Risco, Mario (Universitat Autònoma de Barcelona. Departament de Química) ;
Calatayud, Sara (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Pedrini-Martha, Veronika (University of Innsbruck. Institute of Zoology) ;
Albalat, Ricard (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Palacios Bonilla, Òscar (Universitat Autònoma de Barcelona. Departament de Química) ;
Capdevila Vidal, Mercè (Universitat Autònoma de Barcelona. Departament de Química) ;
Dallinger, Reinhard (University of Innsbruck. Institute of Zoology)
Metallothioneins (MTs) constitute an important family of metal binding proteins. Mollusk MTs, in particular, have been used as model systems to better understand the evolution of their metal binding features and functional adaptation. [...]
2023 - 10.1038/s41598-023-35786-1
Scientific reports, Vol. 13 (June 2023) , art. 8895
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36.
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7 p, 875.8 KB |
Epidemiological and clinical characteristics of children hospitalized due to influenza A and B in the south of Europe, 2010-2016
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Jané, Mireia (Instituto de Salud Carlos III) ;
Vidal, Maria José (Agència de Salut Pública de Catalunya) ;
Soldevila, Núria (Universitat de Barcelona) ;
Romero, Arancha (Universitat de Barcelona) ;
Martínez, Ana (Instituto de Salud Carlos III) ;
Torner, Nuria (Instituto de Salud Carlos III) ;
Godoy, Pere (Instituto de Salud Carlos III) ;
Launes, Cristian (Sant Joan de Deu Children's Hospital) ;
Rius i Gibert, Maria Cristina (Agència de Salut Pública de Barcelona) ;
Marcos, Maria Angeles (Hospital Clínic i Provincial de Barcelona) ;
Domínguez, Ángela (Universitat de Barcelona) ;
Universitat Autònoma de Barcelona
Influenza produces annual epidemics that affect 5-15% of the world population. Complications and hospitalizations are more frequent in childhood. This study describes and analyses the epidemiological and clinical characteristics of children hospitalized due to confirmed influenza in influenza surveillance sentinel hospitals in Catalonia. [...]
2019 - 10.1038/s41598-019-49273-z
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 12853
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37.
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13 p, 6.6 MB |
Integrated gene expression profiles reveal a transcriptomic network underlying the thermogenic response in adipose tissue
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Rodó, Jordi (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Garcia, Miquel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Casaña Lorente, Estefania (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Muñoz, Sergio (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Jambrina Pallarés, Claudia (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Sacristan, Victor (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Franckhauser, Sylvie (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas) ;
Grass Costa, Ignasi (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Jimenez, Veronica (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Obesity and type 2 diabetes are two closely related diseases representing a serious threat worldwide. An increase in metabolic rate through enhancement of non-shivering thermogenesis in adipose tissue may represent a potential therapeutic strategy. [...]
2023 - 10.1038/s41598-023-33367-w
Scientific reports, Vol. 13 (May 2023) , art. 7226
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38.
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12 p, 2.8 MB |
Unexpected silicon localization in calcium carbonate exoskeleton of cultured and fossil coccolithophores
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Bordiga, Manuela (University of Pavia. Department of Earth and Environmental Sciences) ;
Lupi, Claudia (University of Pavia. Department of Earth and Environmental Sciences) ;
Langer, Gerald (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ;
Gianoncelli, Alessandra (Elettra Sincrotrone Trieste) ;
Birarda, Giovanni (Elettra Sincrotrone Trieste) ;
Pollastri, Susanna (Elettra Sincrotrone Trieste) ;
Bonanni, Valentina (Elettra Sincrotrone Trieste) ;
Bedolla, D. E. (AREA Science Park) ;
Vaccari, Lisa (Elettra Sincrotrone Trieste) ;
Gariani, Gianluca (Elettra Sincrotrone Trieste) ;
Cerino, Federica (National Institute of Oceanography and Applied Geophysics-OGS) ;
Cabrini, Marina (National Institute of Oceanography and Applied Geophysics-OGS) ;
Beran, Alfred (National Institute of Oceanography and Applied Geophysics-OGS) ;
Zuccotti, Maurizio (University of Pavia. Department of Biology and Biotechnologies "Lazzaro Spallanzani") ;
Fiorentino, Gabriella (University of Pavia. Department of Biology and Biotechnologies "Lazzaro Spallanzani") ;
Zanoni, Mario (University of Pavia. Department of Biology and Biotechnologies "Lazzaro Spallanzani") ;
Garagna, Silvia (University of Pavia. Department of Biology and Biotechnologies "Lazzaro Spallanzani") ;
Cobianchi, Miriam (University of Pavia. Department of Earth and Environmental Sciences) ;
Di Giulio, Andrea (University of Pavia. Department of Earth and Environmental Sciences)
Coccolithophores, marine calcifying phytoplankton, are important primary producers impacting the global carbon cycle at different timescales. Their biomineral structures, the calcite containing coccoliths, are among the most elaborate hard parts of any organism. [...]
2023 - 10.1038/s41598-023-34003-3
Scientific reports, Vol. 13 (May 2023) , art. 7417
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39.
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11 p, 4.7 MB |
Magnetic properties of FeGa/Kapton for flexible electronics
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Pradhan, Gajanan (Istituto Nazionale di Ricerca Metrologica) ;
Celegato, Federica (Istituto Nazionale di Ricerca Metrologica) ;
Barrera, Gabriele (Istituto Nazionale di Ricerca Metrologica) ;
Olivetti, Elena Sonia (Istituto Nazionale di Ricerca Metrologica) ;
Coisson, Marco (Istituto Nazionale di Ricerca Metrologica) ;
Hajduček, Jan (Brno University of Technology. Central European Institute of Technology) ;
Arregi, Jon Ander (Brno University of Technology. Central European Institute of Technology) ;
Čelko, Ladislav (Brno University of Technology. Central European Institute of Technology) ;
Uhlíř, Vojtěch (Brno University of Technology. Central European Institute of Technology) ;
Rizzi, Paola (Università di Torino. Dipartimento di Chimica) ;
Tiberto, Paola (Istituto Nazionale di Ricerca Metrologica)
Flexible materials have brought up a new era of application-based research in stretchable electronics and wearable devices in the last decade. Tuning of magnetic properties by changing the curvature of devices has significant impact in the new generation of sensor-based technologies. [...]
2022 - 10.1038/s41598-022-21589-3
Scientific reports, Vol. 12 (October 2022) , art. 17503
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