Anemia in patients with high-risk acute coronary syndromes admitted to Intensive Cardiac Care Units
Lorente, Victòria (Hospital Universitari de Bellvitge)
Aboal, Jaime (Hospital Universitari de Girona Doctor Josep Trueta)
García, Cosme (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Sans-Roselló, Jordi (Institut d'Investigació Biomèdica Sant Pau)
Sambola, Antonia (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Andrea, Rut (Hospital Clínic i Provincial de Barcelona)
Tomás, Carlos (Hospital Arnau de Vilanova (Lleida, Catalunya))
Bonet, Gil (Hospital Universitari Joan XXIII de Tarragona)
Viñas, David (Hospital Universitari de Girona Doctor Josep Trueta)
El Ouaddi, Nabil (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Montero, Santiago (Institut d'Investigació Biomèdica Sant Pau)
Cantalapiedra, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Pujol, Margarida (Hospital Clínic i Provincial de Barcelona)
Hernández, Isabel (Hospital Arnau de Vilanova (Lleida, Catalunya))
Pérez-Rodriguez, María (Hospital Universitari Joan XXIII de Tarragona)
Llaó, Isaac (Hospital Universitari de Bellvitge)
Sánchez-Salado, José C.. (Hospital Universitari de Bellvitge)
Gual, Miquel (Hospital Universitari de Bellvitge)
Ariza-Solé, Albert (Hospital Universitari de Bellvitge)
Universitat Autònoma de Barcelona

Fecha:	2020
Resumen:	Little information exists about the role of anemia in patients with acute coronary syndromes (ACS) admitted to Intensive Cardiac Care Units (ICCU). The aim of this study was to assess the prevalence of anemia and its impact on management and outcomes in this clinical setting. All consecutive patients admitted to eight different ICCUs with diagnosis of non-ST segment elevation ACS (NSTEACS) were prospectively included. Anemia was defined as hemoglobin < 130 g/L in men and < 120 g/L in women. The association between anemia and mortality or readmission at six months was assessed by the Cox regression method. A total of 629 patients were included. Mean age was 66. 6 years. A total of 197 patients (31. 3%) had anemia. Coronary angiography was performed in most patients (96. 2%). Patients with anemia were significantly older, with a higher prevalence of comorbidities, poorer left ventricle ejection fraction and higher GRACE score values. Patients with anemia underwent less often coronary angiography, but underwent more often intraaortic counterpulsation, non-invasive mechanical ventilation and renal replacement therapies. Both ICCU and hospital stay were significantly longer in patients with anemia. Both the incidence of mortality (HR = 3. 36, 95% CI: 1. 43-7. 85, P = 0. 001) and the incidence of mortality/readmission were significantly higher in patients with anemia (HR = 2. 80, 95% CI: 2. 03-3. 86, P = 0. 001). After adjusting for confounders, the association between anemia and mortality/readmission remained significant (P = 0. 031). Almost one of three NSTEACS patients admitted to ICCU had anemia. Most patients underwent coronary angiography. Anemia was independently associated to poorer outcomes at 6 months.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra, i la creació d'obres derivades, sempre que no sigui amb finalitats comercials i que es distribueixin sota la mateixa llicència que regula l'obra original. Cal que es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Acute coronary syndromes ; Anemia ; Intensive cardiac care units ; Prognosis
Publicado en:	Journal of Geriatric Cardiology : JGC, Vol. 17 (january 2020) , p. 35-42

DOI: 10.11909/j.issn.1671-5411.2020.01.006
PMID: 32133035

8 p, 324.9 KB

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Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut de Recerca Sant Pau
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