A randomized, phase 2 study of deoxyuridine triphosphatase inhibitor, TAS-114, in combination with S-1 versus S-1 alone in patients with advanced non-small-cell lung cancer
Yamamoto, Nobuyuki (Wakayama Medical University. Third Department of Internal Medicine)
Hayashi, Hidetoshi (Kindai University Faculty of Medicine. Department of Medical Oncology)
Planchard, David (Institut Gustave Roussy (Villejuif, França))
Morán, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Gregorc, Vanesa (IRCCS Ospedale San Raffaele. Department of Oncology, Division of Experimental Medicine)
Dowell, Jonathan (University of Texas Southwestern Medical Center. Department of Internal Medicine)
Sakai, Hiroshi (Saitama Cancer Center. Department of Thoracic Oncology)
Yoh, Kiyotaka (National Cancer Center Hospital East. Department of Thoracic Oncology)
Nishio, Makoto (The Cancer Institute Hospital of the Japanese Foundation for Cancer Research. Department of Thoracic Medical Oncology)
Cortot, Alexis B. (Centre Hospitalier Universitaire de Lille. Thoracic Oncology Department)
Benhadji, Karim A. (Taiho Oncology, Inc. Department of Clinical Development)
Soni, Nital (Taiho Oncology, Inc. Department of Clinical Development)
Huang, Jinhong (Taiho Pharmaceutical Co., Ltd. Department of Pharmacovigilance)
Makris, Lukas (Stathmi, Inc, 125 Brownsburg Rd, New Hope, PA 18938 USA)
Cedrés, Susana (Vall d'Hebron Institut d'Oncologia)
Universitat Autònoma de Barcelona

Date:	2020
Abstract:	The online version of this article (10. 1007/s10637-020-00930-5) contains supplementary material, which is available to authorized users.
Note:	Altres ajuts: The authors would like to thank Keyra Martinez Dunn, MD and Sarah Bubeck, PhD, of Edanz Medical Writing, for providing medical writing support which was funded by Taiho Pharmaceutical Co., Ltd.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	DUTPase ; Non-small-cell lung cancer ; 5-fluorouracil ; Progression-free survival
Published in:	Investigational New Drugs, Vol. 38 (april 2020) , p. 1588-1597, ISSN 1573-0646

DOI: 10.1007/s10637-020-00930-5
PMID: 32246224

10 p, 2.7 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles