visitant ::
identificació
|
|||||||||||||||
Cerca | Lliura | Ajuda | Servei de Biblioteques | Sobre el DDD | Català English Español |
Pàgina inicial > Articles > Articles publicats > Characterisation of sperm piRNAs and their correlation with semen quality traits in swine |
Data: | 2021 |
Resum: | Piwi-interacting RNAs (piRNAs) are a class of non-coding RNAs that are essential in the transcriptional silencing of transposable elements and warrant genome stability in the mammalian germline. In this study, we have identified piRNAs in porcine sperm using male germline and zygote datasets from human, mice, cow and pig, and evaluated the relation between their abundances and sperm quality traits. In our analysis, we identified 283 382 piRNAs, 1355 of which correlated with P ≤ 0. 01 to at least one semen quality trait. Fifty-seven percent of the correlated piRNAs mapped less than 50 kb apart from any other piRNA in the pig genome. Furthermore, piRNA location was significantly enriched near long interspersed nuclear elements. Moreover, some of the significant piRNAs mapped within or close to genes relevant for fertility or spermatogenesis such as CSNK1G2 and PSMF1. |
Ajuts: | Ministerio de Economía y Competitividad AGL2013-44978-R and Ministerio de Economía y Competitividad AGL2017-86946-R Agència de Gestió d'Ajuts Universitaris i de Recerca 2014/SGR-1528 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-1060 Ministerio de Economía y Competitividad SEV-2015-0533 Ministerio de Economía y Competitividad BES-2014-070560 |
Nota: | Altres ajuts: CERCA Programme/Generalitat de Catalunya |
Drets: | Tots els drets reservats. |
Llengua: | Anglès |
Document: | Article ; recerca ; Versió acceptada per publicar |
Matèria: | Piwi-interacting RNAs ; Repeat elements ; RNA-seq ; Semen quality ; Sperm ; Swine |
Publicat a: | Animal Genetics, Vol. 52, Issue 1 (February 2021) , p. 114-120, ISSN 1365-2052 |
Article. Postprint 35 p, 524.5 KB |
Supplement Material 1 4 p, 187.4 KB |
Supplement Material 2. Arxiu xlsx 173.7 KB |