Patterns of multimorbidity and risk of disability in community-dwelling older persons
Marengoni, Alessandra (Karolinska Institutet and Stockholm University. Aging Research Center, Department of Neurobiology, Care Sciences and Society)
Akugizibwe, Roselyne (Karolinska Institutet and Stockholm University. Aging Research Center, Department of Neurobiology, Care Sciences and Society)
Vetrano, Davide L. (Università Cattolica del Sacro Cuore. Centro Medicina Dell'Invecchiamento, Fondazione Policlinico Universitario "A. Gemelli" IRCCS)
Roso-Llorach, Albert (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Onder, Graziano (Istituto Superiore Di Sanità. Department of Cardiovascular, Endocrine-Metabolic Diseases and Aging)
Welmer, Anna-Karin (Stockholm Gerontology Research Center)
Calderón-Larrañaga, Amaia (Karolinska Institutet and Stockholm University. Aging Research Center, Department of Neurobiology, Care Sciences and Society)
Universitat Autònoma de Barcelona

Date:	2021
Abstract:	The aim was to analyze the association between specific patterns of multimorbidity and risk of disability in older persons. Data were gathered from the Swedish National Study on Aging and Care in Kungsholmen (SNAC-K); 2066 60 + year-old participants living in the community and free from disability at baseline were grouped according to their multimorbidity patterns and followed-up for six years. The association between multimorbidity patterns and disability in basic (ADL) and instrumental (IADL) activities of daily living was examined through multinomial models. Throughout the follow-up, 434 (21. 0%) participants developed at least one ADL and 310 (15. 0%) at least one IADL. Compared to the unspecific pattern, which included diseases not exceeding their expected prevalence in the total sample, belonging to the cardiovascular/anemia/dementia, the sensory impairment/cancer and the musculoskeletal/respiratory/gastrointestinal patterns was associated with a higher risk of developing both ADL and IADL, whereas subjects in the metabolic/sleep disorders pattern showed a higher risk of developing only IADL. Multimorbidity patterns are differentially associated with incident disability, which is important for the design of future prevention strategies aimed at delaying functional impairment in old age, and for a better healthcare resource planning.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Multimorbidity patterns ; Disability ; Older persons
Published in:	Aging Clinical and Experimental Research, Vol. 33 (february 2021) , p. 457-462, ISSN 1720-8319

DOI: 10.1007/s40520-020-01773-z
PMID: 33580869

6 p, 500.2 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
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