Pretreatment with ibrutinib reduces cytokine secretion and limits the risk of obinutuzumab-induced infusion-related reactions in patients with CLL : analysis from the iLLUMINATE study
Greil, Richard (Salzburg Cancer Research Institute-CCCIT, Cancer Cluster Salzburg. IIIrd Medical Department Paracelsus Medical University)
Tedeschi, Alessandra (Department of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy)
Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau)
Anz, Bertrand (Tennessee Oncology. Department of Medical Oncology)
Larratt, Loree (University of Alberta Hospital. Department of Clinical Hematology)
Simkovic, Martin (University Hospital Hradec Kralove (República Txeca))
Gill, Devinder (Princess Alexandra Hospital. Department of Clinical Hematology)
Gribben, John G. (Queen Mary University of London, Barts Cancer Institute. Centre for Haemato-Oncology)
Flinn, Ian W. (Sarah Cannon Research Institute/Tennessee Oncology)
Wang, Zhengyuan (Pharmacyclics LLC, an AbbVie Company. Translational Medicine)
Cheung, Leo W. K. (Pharmacyclics LLC, an AbbVie Company. Translational Medicine)
Nguyen, Aaron N. (Pharmacyclics LLC, an AbbVie Company. Translational Medicine)
Zhou, Cathy (Pharmacyclics LLC, an AbbVie Company. Biostatistics)
Styles, Lori (Pharmacyclics LLC, an AbbVie Company. Clinical Science)
Demirkan, Fatih (Dokuz Eylül University. Department of Hematology)
Universitat Autònoma de Barcelona

Date:	2021
Abstract:	The online version contains supplementary material available at 10. 1007/s00277-021-04536-6.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Infusion-related reactions ; Ibrutinib ; Obinutuzumab ; Cytokines
Published in:	Annals of Hematology, Vol. 100 (may 2021) , p. 1733-1742, ISSN 1432-0584

DOI: 10.1007/s00277-021-04536-6
PMID: 34018029

10 p, 631.8 KB

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Articles > Research articles
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