Non-Invasive Cerebellar Stimulation in Neurodegenerative Ataxia : A Literature Review
Benussi, Alberto (University of Brescia)
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann)
Borroni, Barbara (University of Brescia)

Date:	2020
Abstract:	Cerebellar ataxias are a heterogenous group of degenerative disorders for which we currently lack effective and disease-modifying interventions. The field of non-invasive brain stimulation has made much progress in the development of specific stimulation protocols to modulate cerebellar excitability and try to restore the physiological activity of the cerebellum in patients with ataxia. In light of limited evidence-based pharmacologic and non-pharmacologic treatment options for patients with ataxia, several different non-invasive brain stimulation protocols have emerged, particularly employing repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) techniques. In this review, we summarize the most relevant rTMS and tDCS therapeutic trials and discuss their implications in the care of patients with degenerative ataxias.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Transcranial magnetic stimulation ; Transcranial direct current stimulation ; Non-invasive brain stimulation ; Neurodegenerative ataxia ; Cerebellar ataxia ; Therapy
Published in:	International journal of molecular sciences, Vol. 21 (march 2020) , ISSN 1422-0067

DOI: 10.3390/ijms21061948
PMID: 32178459

14 p, 300.2 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles