Theoretical frameworks and approaches used within the Reserve, Resilience and Protective Factors professional interest area of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment
Bartrés-Faz, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Arenaza-Urquijo, Eider (Pasqual Maragall Foundation)
Ewers, Michael (LMU Munich. University Hospital)
Belleville, Sylvie (Université de Montréal)
Chételat, G. (Normandie University)
Franzmeier, Nicolai (LMU Munich. University Hospital)
Gonneaud, Julie (McGill University)
de Echevarri, José María González (Pasqual Maragall Foundation)
Okonkwo, Ozioma (University of Wisconsin-Madison)
Schultz, Stephanie (University of Wisconsin-Madison)
Valenzuela, Michael (University of New South Wales)
Stern, Yaakov (Columbia University)
Vemuri, Prashanthi (Mayo Clinic Rochester Minnesota)

Date:	2020
Abstract:	Reserve, resilience, maintenance, and related concepts are intensely debated in aging and Alzheimer's disease research. Through a short survey, we gathered information about theoretical concepts and methodologies used among research groups of the Reserve, Resilience, and Protective Factors Professional Interest Area of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment. Overall 53 research groups responded. Reserve and resilience were the most frequently used conceptual frameworks. Education, occupation, leisure, and social activities were frequently used as measures, as were longitudinal designs. Neuropsychological assessments were almost universal, and usage of imaging biomarkers was frequent. In observational-epidemiological study designs, resilience and reserve together (vs reserve alone) were commonly used as theoretical frameworks. We provide a first description of concepts and methodologies used among reserve and resilience researchers. This will inform initiatives aiming to reach consensus on terminology and applications to establish common definitions.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Brain reserve ; Cognitive reserve ; Maintenance ; Methodologies ; Outcome measures ; Resilience ; Techniques
Published in:	Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 12 (november 2020) , ISSN 2352-8729

DOI: 10.1002/dad2.12115
PMID: 33204812

6 p, 668.6 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles