Intensive care unit patients with lower respiratory tract nosocomial infections : the ENIRRIs project
De Pascale, Gennaro (Università Cattolica del Sacro Cuore)
Ranzani, Otavio T. (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Nseir, Saad (CHU Lille)
Chastre, Jean (Groupe Hospitalier Pitié-Salpêtrière)
Welte, Tobias (Hannover Medical School)
Antonelli, Massimo (Università Cattolica del Sacro Cuore)
Navalesi, Paolo (Università della Magna Graecia)
Garofalo, Eugenio (Università della Magna Graecia)
Bruni, Andrea (Università della Magna Graecia)
Coelho, Luis (New University of Lisbon)
Skoczynski, Szymon (Medical University of Silesia)
Longhini, Federico (Sant'Andrea Hospital)
Taccone, Fabio Silvio (Université Libre de Bruxelles)
Grimaldi, David (Université Libre de Bruxelles)
Salzer, Helmut J. F. (University of Lübeck)
Lange, Christoph (University of Lübeck)
Froes, Filipe (Hospital Pulido Valente)
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Díaz-Aparicio, Efren (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Vallés, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Rodríguez, Alejandro (Hospital Universitari Joan XXIII de Tarragona)
Panigada, Mauro (Ospedale Maggiore Policlinico)
Comellini, Vittoria (Alma Mater University)
Fasano, Luca (Alma Mater University)
Soave, Paolo M. (Università Cattolica del Sacro Cuore)
Spinazzola, Giorgia (Università Cattolica del Sacro Cuore)
Luyt, Charles-Edouard (Groupe Hospitalier Pitié-Salpêtrière)
Álvarez Lerma, Francisco (Institut Hospital del Mar d'Investigacions Mèdiques)
Marin, Judith (Institut Hospital del Mar d'Investigacions Mèdiques)
Masclans, Joan R (Institut Hospital del Mar d'Investigacions Mèdiques)
Chiumello, Davide (Università degli Studi di Milano)
Pezzi, Angelo (Università degli Studi di Milano)
Schultz, Marcus (Mahidol University)
Mohamed, Hafiz (St. James's Hospital (Irlanda))
Van Der Eerden, Menno (Erasmus MC (Rotterdam))
Hoek, Roger A. S. (Erasmus MC (Rotterdam))
Gommers, D. A. M. P. J. (Erasmus MC (Rotterdam))
Pasquale, Marta Di (IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico)
Civljak, Rok (University of Zagreb School of Medicine)
Kutleša, Marko (University of Zagreb School of Medicine)
Bassetti, Matteo (Medicine University of Udine and Santa aria Misericordia Hospital)
Dimopoulos, George (University General Hospital Attikon (Haidari, Grècia))
Nava, Stefano (Alma Mater University)
Rios, Fernando (Hospital Nacional Profesor A Posadas (Argentina))
Zampieri, Fernando G. (Hospital do Coração (Brasil))
Povoa, Pedro (New University of Lisbon)
Bos, Lieuwe D.. (Academic Medical Center (Holanda))
Aliberti, Stefano (IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico)
Torres, Antoni (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Martín-Loeches, Ignacio (St. James's Hospital (Irlanda))
Universitat Autònoma de Barcelona

Data:	2017
Resum:	The clinical course of intensive care unit (ICU) patients may be complicated by a large spectrum of lower respiratory tract infections (LRTI), defined by specific epidemiological, clinical and microbiological aspects. A European network for ICU-related respiratory infections (ENIRRIs), supported by the European Respiratory Society, has been recently established, with the aim at studying all respiratory tract infective episodes except community-acquired ones. A multicentre, observational study is in progress, enrolling more than 1000 patients fulfilling the clinical, biochemical and radiological findings consistent with a LRTI. This article describes the methodology of this study. A specific interest is the clinical impact of non-ICU-acquired nosocomial pneumonia requiring ICU admission, non-ventilator-associated LRTIs occurring in the ICU, and ventilator-associated tracheobronchitis. The clinical meaning of microbiologically negative infectious episodes and specific details on antibiotic administration modalities, dosages and duration are also highlighted. Recently released guidelines address many unresolved questions which might be answered by such large-scale observational investigations. In light of the paucity of data regarding such topics, new interesting information is expected to be obtained from our network research activities, contributing to optimisation of care for critically ill patients in the ICU. Methodology for the first European network for ICU-related respiratory infections (ENIRRIs) project.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Publicat a:	ERJ Open Research, Vol. 3 (november 2017) , ISSN 2312-0541

DOI: 10.1183/23120541.00092-2017
PMID: 29164144
PMID: 28717642

5 p, 732.0 KB

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