Acute Sleep Deprivation Induces a Local Brain Transfer Information Increase in the Frontal Cortex in a Widespread Decrease Context
Alonso, Joan Francesc (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina)
Romero, Sergio (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina)
Mañanas, Miguel A. (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina)
Alcalá, Marta (Universitat Politècnica de Catalunya)
Antonijoan Arbós, Rosa Ma (Centro de Investigación Biomédica en Red de Salud Mental)
Giménez, Sandra (Institut d'Investigació Biomèdica Sant Pau)
Universitat Autònoma de Barcelona

Date:	2016
Abstract:	Sleep deprivation (SD) has adverse effects on mental and physical health, affecting the cognitive abilities and emotional states. Specifically, cognitive functions and alertness are known to decrease after SD. The aim of this work was to identify the directional information transfer after SD on scalp EEG signals using transfer entropy (TE). Using a robust methodology based on EEG recordings of 18 volunteers deprived from sleep for 36 h, TE and spectral analysis were performed to characterize EEG data acquired every 2 h. Correlation between connectivity measures and subjective somnolence was assessed. In general, TE showed medium- and long-range significant decreases originated at the occipital areas and directed towards different regions, which could be interpreted as the transfer of predictive information from parieto-occipital activity to the rest of the head. Simultaneously, short-range increases were obtained for the frontal areas, following a consistent and robust time course with significant maps after 20 h of sleep deprivation. Changes during sleep deprivation in brain network were measured effectively by TE, which showed increased local connectivity and diminished global integration. TE is an objective measure that could be used as a potential measure of sleep pressure and somnolence with the additional property of directed relationships.
Grants:	Ministerio de Economía, Industria y Competitividad DPI2014-59049-R
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Prolonged wakefulness ; Sleep deprivation (SD) ; Electroencephalography (EEG) ; Transfer entropy (TE)
Published in:	Sensors (Basel, Switzerland), Vol. 16 (april 2016) , ISSN 1424-8220

DOI: 10.3390/s16040540
PMID: 27089346

14 p, 3.0 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
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