Home > Articles > Published articles > Males and females with first episode psychosis present distinct profiles of social cognition and metacognition |
Date: | 2022 |
Abstract: | Deficits in social cognition and metacognition impact the course of psychosis. Sex diferences in social cognition and metacognition could explain heterogeneity in psychosis. 174 (58 females) patients with frst-episode psychosis completed a clinical, neuropsychological, social cognitive, and metacognitive assessment. Subsequent latent profle analysis split by sex yielded two clusters common to both sexes (a Homogeneous group, 53% and 79. 3%, and an Indecisive group, 18. 3% and 8. 6% of males and females, respectively), a specifc male profle characterized by presenting jumping to conclusions (28. 7%) and a specifc female profle characterized by cognitive biases (12. 1%). Males and females in the homogeneous profle seem to have a more benign course of illness. Males with jumping to conclusions had more clinical symptoms and more neuropsychological defcits. Females with cognitive biases were younger and had lower self-esteem. These results suggest that males and females may beneft from specifc targeted treatment and highlights the need to consider sex when planning interventions. |
Grants: | Ministerio de Ciencia e Innovación PID2019-104830RB-I00 Instituto de Salud Carlos III PI11/01347 Instituto de Salud Carlos III PI14/00044 Instituto de Salud Carlos III PI18/00212 Generalitat de Catalunya SLT006/17/00231 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017-SGR-622 |
Note: | Altres ajuts: Royal Society of New Zealand - Marsden (E2987-3648) ; Obra Social La Caixa (RecerCaixa call 2013) ; Obra Social Sant Joan de Déu BML (RTI2018-100927-J-I00) ; Ministerio Regional de Salud Andaluz PI-0634/2011 ; Ministerio Regional de Salud Andaluz PI-0193/2014 ; Consorcio Centro de Investigación Biomédica en Red (CIBER) (CB/07/09/0028) ; Agència de Qualitat i Avaluació Sanitàries de Catalunya SLT006/17/00231 |
Rights: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. |
Language: | Anglès |
Document: | Article ; recerca ; Versió publicada |
Subject: | Sex differences ; Profiles ; Psychosis ; Schizophrenia ; Social cognition ; Metacognition |
Published in: | European Archives of Psychiatry and Clinical Neuroscience, Vol. 272 (july 2022) , p. 1169-1181, ISSN 1433-8491 |
13 p, 924.3 KB |