Current trends and controversies in the management of warthin tumor of the parotid gland
Quer, Miquel (Institut d'Investigació Biomèdica Sant Pau)
Hernandez-Prera, Juan C. (Department of Pathology. Moffitt Cancer Center)
Silver, Carl E. (Department of Surgery. University of Arizona College of Medicine)
Casasayas, Maria (Institut d'Investigació Biomèdica Sant Pau)
Simo, Ricard S. (Department of Otorhinolaryngology Head and Neck Surgery. Guy's and St Thomas' Hospital NHS Foundation Trust)
Vander Poorten, Vincent (Department of Oncology. Section Head and Neck Oncology. KU Leuven)
Guntinas-Lichius, Orlando (Facial Nerve Center. Jena University Hospital)
Bradley, Patrick (Nottingham University Hospitals NHS Trust (Regne Unit))
Tong-Ng, Wai (Department of Clinical Oncology. LKS Faculty of Medicine. The University of Hong Kong)
Rodrigo, Juan Pablo (Instituto de Investigación Sanitaria del Principado de Asturias (ISPA). Instituto Universitario de Oncología del Principado de Asturias (IUOPA). University of Oviedo CIBERONC-ISCIII)
Mäkitie, Antti A (Karolinska University Hospital and Karolinska Institutet (Suècia))
Rinaldo, Alessandra (University of Udine School of Medicine)
Kowalski, Luiz Paulo (Head and Neck Surgery and Otorhinolaryngology Department. A.C. Camargo Cancer Center)
Sanabria, Alvaro (Department of Surgery. School of Medicine. Universidad de Antioquia. IPS Universitaria-Hospital Universitario San Vicente Fundación)
de Bree, Remco (University Medical Center Utrecht)
Takes, Robert P. (Radboud University Medical Center)
López, Fernando (Instituto de Investigación Sanitaria del Principado de Asturias (ISPA). Instituto Universitario de Oncología del Principado de Asturias (IUOPA). University of Oviedo CIBERONC-ISCIII)
Olsen, Kerry D. (Department of Otorhinolaryngology. Mayo Clinic)
Shaha, Ashok R. (Head and Neck Service. Memorial Sloan-Kettering Cancer Center)
Ferlito, Alfio (Coordinator of the International Head and Neck Scientific Group)
Universitat Autònoma de Barcelona

Data:	2021
Resum:	Purpose: To review the current options in the management of Warthin tumors (WTs) and to propose a working management protocol. Methods: A systematic literature search was conducted using PubMed and ScienceDirect database. A total of 141 publications were selected and have been included in this review. Publications were selected based on relevance, scientific evidence, and actuality. Results: The importance of parotid WTs is increasing due to its rising incidence in many countries, becoming the most frequently encountered benign parotid tumor in certain parts of the world. In the past, all WTs were treated with surgery, but because of their slow growth rate, often minimal clinical symptoms, and the advanced age of many patients, active observation has gradually become more widely used. In order to decide on active surveillance, the diagnosis of WT must be reliable, and clinical, imaging, and cytological data should be concordant. There are four clear indications for upfront surgery: uncertain diagnosis; cosmetic problems; clinical complaints, such as pain, ulceration, or recurrent infection; and the patient's wish to have the tumor removed. In the remaining cases, surgery can be elective. Active surveillance is often suggested as the first approach, with surgery being considered if the tumor progresses and/or causes clinical complaints. The extent of surgery is another controversial topic, and the current trend is to minimize the resection using partial parotidectomies and extracapsular dissections when possible. Recently, non-surgical options such as microwave ablation, radiofrequency ablation, and ultrasound-guided ethanol sclerotherapy have been proposed for selected cases. Conclusions: The management of WT is gradually shifting from superficial or total parotidectomy to more conservative approaches, with more limited resections, and to active surveillance in an increasing number of patients. Additionally, non-surgical treatments are emerging, but their role needs to be defined in future studies.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Matèria:	Warthin tumor ; Papillary cystadenoma lymphomatosum ; Cystadenolymphoma ; Adenolymphoma ; Lymphomatous adenoma ; Parotid tumor
Publicat a:	Diagnostics, Vol. 11 Núm. 8 (august 2021) , p. 1467, ISSN 2075-4418

DOI: 10.3390/diagnostics11081467
PMID: 34441400

14 p, 2.2 MB

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Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències de la salut i biociències > Institut de Recerca Sant Pau
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