Recent advances in the management of patients with non-muscle-invasive bladder cancer using a multidisciplinary approach : Practical recommendations from the spanish oncology genitourinary (sogug) working group
Rubio-briones, José (Hospital Vithas Valencia 9 de Octubre)
Algaba, Ferran (Institut d'Investigació Biomèdica Sant Pau)
Gallardo, Enrique (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Marcos-Rodríguez, José Antonio (Hospital Universitario Virgen Macarena (Sevilla, Andalusia))
Climent, Miguel Ángel (Medical Oncology Service. Fundación Instituto Valenciano de Oncología)
Gomez-Caamaño, Antonio (Hospital Clínico Universitario (Santiago de Compostela, Galícia))
Garcia Vicente, Ana M. (Spanish Oncology Genitourinary)
Maroto Rey, Pablo (Institut d'Investigació Biomèdica Sant Pau)
Rodriguez Antolín, Alfredo (Spanish Oncology Genitourinary)
Sanz, Julian (Spanish Oncology Genitourinary)
Vera González, Maria Almudena (Spanish Oncology Genitourinary)
González-del-Alba, Aránzazu (Spanish Oncology Genitourinary)
Conde Moreno, Antonio José (Spanish Oncology Genitourinary)
González-Haba, Eva (Spanish Oncology Genitourinary)
González-Peramato, Pilar (Spanish Oncology Genitourinary)
Linares Espinós, Estefania (Spanish Oncology Genitourinary)
López-Beltran, Antonio (Spanish Oncology Genitourinary)
Pelechano, Paula (Spanish Oncology Genitourinary)
Garrido, Marga (Spanish Oncology Genitourinary)
Gironés Sarrió, Regina (Spanish Oncology Genitourinary)
Zapatero, Almudena (Spanish Oncology Genitourinary)
Arranz Alija, Jose Ángel (Spanish Oncology Genitourinary)
Universitat Autònoma de Barcelona

Date:	2021
Abstract:	On the basis of the discussion of the current state of research on relevant topics of non-muscle-invasive bladder cancer (NMIBC) among a group of experts of the Spanish Oncology Gen-itourinary (SOGUG) Working Group, recommendations were proposed to overcome the challenges posed by the management of NMIBC in clinical practice. A unified definition of the term 'microhe-maturia' and the profile of the patient at risk are needed. Establishing a 'hematuria clinic' would contribute to a centralized and more efficient evaluation of patients with this clinical sign. Second or repeated transurethral resection (re-TUR) needs to be defined, including the time window after the first procedure within which re-TUR should be performed. Complete tumor resection is man-datory when feasible, with specification of the presence or absence of muscle. Budding should be used as a classification system, and stratification of T1 tumors especially in extensive and deep tu-mors, is advisable. The percentage of the high-grade component should always be reported, and, in multiple tumors, grades should be reported separately. Luminal and basal subtypes can be identi-fied because of possibly different clinical outcomes. Molecular subtypes and immunotherapy are incorporated in the management of muscle-invasive bladder cancer but data on NMIBC are still preliminary.
Note:	Altres ajuts: AstraZeneca.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Subject:	Non-muscle-invasive bladder cancer ; Microhematuria ; Transurethral resection ; Histological variants ; Molecular subtypes ; Immunotherapy
Published in:	Cancers, Vol. 13 Núm. 19 (October 2021) , p. 4762, ISSN 2072-6694

DOI: 10.3390/cancers13194762
PMID: 34638247

17 p, 1.2 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles