Chronic nodular prurigo : A european cross-sectional study of patient perspectives on therapeutic goals and satisfaction
Pereira, Manuel Pedro (University Hospital of Münster (Alemanya))
Zeidler, Claudia (University Hospital of Münster (Alemanya))
Wallengren, Joanna (Department of Clinical Sciences Lund. Dermatology and Venereology. Lund University. Lund Sweden. Skåne University Hospital)
Halvorsen, Jon Anders (Oslo University Hospital (Oslo, Noruega))
Weisshaar, Elke (Department of Social Medicine. Occupational and Environmental Dermatology. University of Heidelberg)
Garcovich, Simone (Università Cattolica del Sacro Cuore)
Misery, Laurent (University Hospital of Brest)
Brenaut, Emilie (Department of Dermatology. University Hospital of Brest)
Savk, Ekin (Department of Dermatology. Aydın Adnan Menderes University)
Potekaev, Nikolay (Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology)
Lvov, Andrey (Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology)
Bobko, Svetlana (Moscow Scientific and Practical Center of Dermatovenereology and Cosmetology)
Szepietowski, Jacek C. (Wroclaw Medical University. Department of Dermatology. Venereology and Allergology)
Reich, Adam (University of Rzeszów. Department of Dermatology)
Bożek, Agnieszka (University of Information Technology and Management. School of Medicine)
Legat, Franz Josef (Medical University of Graz. Department of Dermatology)
Metz, Martin (Charité - Universitätsmedizin Berlin)
Streit, Markus (Department of Dermatology. Kantonsspital Aarau)
Serra-Baldrich, E (Institut d'Investigació Biomèdica Sant Pau)
Gonçalo, Margarida (University of Coimbra. Department of Dermatology)
Storck, Michael (University of Münster. Institute of Medical Informatics)
Nau, Teresa (University Hospital of Münster (Alemanya))
Hoffmann, Vincent (University Hospital of Münster (Alemanya))
Steinke, Sabine (University Hospital of Münster (Alemanya))
Greiwe, Ina (University Hospital of Münster (Alemanya))
Dugas, Martin (Institute of Medical Informatics. University of Münster)
Augustin, Matthias (University Medical Center Hamburg-Eppendorf)
Ständer, Sonja (University Hospital Muenster (Alemanya))

Data:	2021
Resum:	Chronic nodular prurigo is characterized by recalcitrant itch. Patient perspectives on therapeutic goals, satisfaction with therapy and efficacy of therapeutic regimens for this condition are unknown. This questionnaire study examined these issues in 406 patients with chronic nodular prurigo from 15 European dermatological centres. Improvements in itch, skin lesions and sleep were the most important goals. Emollients, topical corticosteroids and antihistamines were the most frequently used treatments, while a minority of patients were prescribed potent medications, such as systemic immunosuppressants and gabapentinoids. Most patients were not satisfied with their previous therapy (56. 8%), while 9. 8% did not receive any therapy despite having active disease. A substantial number of respondents (28. 7%) considered none of the therapeutic options effective. Although chronic nodular prurigo is a severe disease, most patients were not treated with potent systemic drugs, which may contribute to the high levels of dissatisfaction and disbelief in available therapies. Specific guidelines for chronic nodular prurigo and the development of novel therapies are necessary to improve care.
Nota:	Altres ajuts: European Academy of Dermatology and Venereology (EADV, 2016-012); Galderma S.A; Kiniksa Pharmaceuticals; Menlo Therapeutics.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Nodular prurigo ; Chronic nodular prurigo ; Patient-­reported outcome ; Itch ; Pruritus ; Therapy
Publicat a:	Acta dermato-venereologica, Vol. 101 Núm. 2 (2021) , p. adv00403, ISSN 1651-2057

DOI: 10.2340/00015555-3726
PMID: 33320272

7 p, 720.5 KB

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