Determinants of Depressive Symptoms in People Living with HIV : Findings from a Population-Based Study with a Gender Perspective
Bayes-Marin, Ivet (Universitat Internacional de Catalunya)
Egea Cortés, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Palacio-Vieira, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Bruguera Riera, Andreu (Universitat Autònoma de Barcelona. Departament de Pediatria, d'Obstetrícia i Ginecologia i de Medicina Preventiva)
Mesías-Gazmuri, Jocelyn (Universitat Autònoma de Barcelona. Departament de Pediatria, d'Obstetrícia i Ginecologia i de Medicina Preventiva)
Llibre, Josep M.. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Fernández, Emma (Hospital Clínic i Provincial de Barcelona)
Imaz, Arkaitz (Institut d'Investigació Biomèdica de Bellvitge)
Forero, Carlos G. (Universitat Internacional de Catalunya)
Agustí, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Arbones-Fernández, Laia (Hospital de Mataró. Consorci Sanitari del Maresme)
Miró, José M. (Universitat de Barcelona)
Casabona-Barbarà, Jordi (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública)
Reyes-Ureña, Juliana (Generalitat de Catalunya)

Date:	2023
Abstract:	Depressive symptoms are common among people living with HIV (PLWH). The aim of this study was to identify the determinants of depressive symptoms in PLWH in Spain. A total of 1060 PLWH participated in this cross-sectional study and completed the Patient Health Questionnaire-9. The odds ratios for the presence of depressive symptoms were analyzed in a multivariable logistic regression model, including sociodemographic data, comorbidities, health-related behaviors, and social-environment-related variables. We found an overall prevalence of depressive symptoms of 21. 42%; by subgroup, namely men, women, and transgender persons, prevalence was 18. 13%, 32. 81%, and 37. 14%, respectively. Moreover, social isolation (OR = 1. 05 [CI, 1. 02-1. 08]) and poor physical and mental quality of life (OR = 1. 06 [CI, 1. 02-1. 09] and OR = 1. 13 [CI, 1. 09-1. 17], respectively) were associated with depressive symptoms. As protective factors, we identified serodisclosure to more people (vs. none; OR = 0. 39 [CI, 0. 17-0. 87]), satisfaction with social roles (OR = 0. 86 [CI, 0. 79-0. 94]), better cognitive function (OR = 0. 92 [CI, 0. 89-0. 95]), and sexualized drug use once in a lifetime (OR = 0. 52 [CI, 0. 29-0. 93]). This study showed a high prevalence of depressive symptoms in PLWH, especially among women and transgender people. The association between psychosocial variables and depressive symptoms highlights the multidimensionality of the problem and identifies areas for intervention. This study found that the management of mental health issues is an area that needs to be improved and tailored to specific groups, with the aim of enhancing the well-being of PLWH.
Grants:	"la Caixa" Foundation COVIHCAT
Note:	Altres ajuts: Fundació La Marató de TV3 (239/C/2018)
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Depressive symptoms ; Health-related quality of life ; HIV/AIDS ; Gender ; Transgender
Published in:	International journal of environmental research and public health, Vol. 20 (february 2023) , ISSN 1660-4601

DOI: 10.3390/ijerph20043687
PMID: 36834381

19 p, 436.8 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles