Hernia enlargement and pancreatitis in a patient with short bowel syndrome treated with teduglutide Crecimiento de hernias y pancreatitis en una paciente con síndrome de intestino corto tratada con teduglutida
Conejo, Irene (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Mas-Malagarriga, Núria (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Riera, Pau (Institut d'Investigació Biomèdica Sant Pau)
Cardenete, Juana (Institut d'Investigació Biomèdica Sant Pau)
Puig-Piña, Rocío (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Rodríguez-Blanco, Manuel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
De Pourcq, Jan T (Institut d'Investigació Biomèdica Sant Pau)

Date:	2022
Abstract:	Introduction: teduglutide (TED) is indicated for the treatment of patients with short-bowel syndrome (SBS) who are dependent on parenteral support. Case report: we report the case of a 60-year-old woman with SBS treated with TED. She had previously undergone multiple surgical resections due to Crohn's disease. Her remnant bowel included only the duodenum and 50-60 centimeters of jejunum. The patient was dependent on intravenous fluids (2,320 mL/48 h) and had a high stoma output (3,000 mL/day). After four months of TED the jejunostomy output had decreased to 2,200 mL/day with a thicker consistency, and intravenous fluid therapy was reduced to 2,010 mL/48 h. TED was withdrawn due to acute pancreatitis and enlargement of two supraumbilical hernias with high strangulation risk. Discussion: pancreatitis has been reported in clinical studies, and determination of amylase and lipase is recommended in all patients receiving TED. In contrast, there are no recommendations for the surveillance of hernia enlargement in patients on TED therapy, but we suggest the need for surveillance based on this case report.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra, i la creació d'obres derivades, sempre que no sigui amb finalitats comercials i que es distribueixin sota la mateixa llicència que regula l'obra original. Cal que es reconegui l'autoria de l'obra original.
Language:	Castellà
Document:	Altres ; recerca ; Versió publicada
Subject:	Teduglutide ; Short bowel syndrome ; Pancreatitis ; Hernia enlargement ; Case report
Published in:	Nutricion Hospitalaria, Vol. 39 Núm. 1 (January-February 2022) , p. 230-232, ISSN 1699-5198

DOI: 10.20960/nh.03879
PMID: 34903028

3 p, 185.3 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles