Efficacy and Safety of Topical Application of Olive Oil for Preventing Pressure Ulcers : A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Hernández-Vásquez, Akram (Centro de Excelencia en Investigaciones Económicas y Sociales en Salud. Vicerrectorado de Investigación. Universidad San Ignacio de Loyola)
Visconti-Lopez, Fabriccio J. (Facultad de Ciencias de la Salud. Universidad Peruana de Ciencias Aplicadas)
Cabanillas-Ramirez, Cielo (Facultad de Ciencias de la Salud. Universidad Peruana de Ciencias Aplicadas)
Díaz-Seijas, Deysi (Instituto Nacional Cardiovascular INCOR. EsSalud)
Meléndez-Escalante, Jessica (Instituto Nacional Cardiovascular INCOR. EsSalud)
Comandé, Daniel (Instituto de Efectividad Clínica y Sanitaria (IECS-CONICET))
Santero, Marilina (Institut d'Investigació Biomèdica Sant Pau)

Date:	2022
Abstract:	The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized controlled trials (RCTs) involving patients at risk of developing PUs, testing the topical application of olive oil versus other products for PU prevention. We assessed the risk of bias using the RoB 2 tool, and the certainty of the evidence with GRADE. Four RCTs met the eligibility criteria. All studies were judged at a low risk of bias overall. The meta-analysis showed that the clinical efficacy of olive oil for prevention occurs by reducing the incidence of PUs (RR = 0. 56, 95% CI = 0. 30 to 0. 79, I = 0%); with no differences in adverse effects, it may be associated with a shorter development time of PUs and shorter hospital stays. The certainty of the evidence assessed by the GRADE approach was moderate and low. The topical application of olive oil is effective and safe in reducing the incidence of PUs compared to other treatments. These findings could provide new insights into olive oil as a preventive and alternative treatment for PUs as it is accessible and inexpensive compared to other products.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article de revisió ; recerca ; Versió publicada
Subject:	Humans ; Pressure ulcer ; Bedsore ; Olive oil ; Prevention and control ; GRADE approach ; Randomized controlled trial
Published in:	International journal of environmental research and public health, Vol. 19 Núm. 22 (november 2022) , p. 14921, ISSN 1660-4601

DOI: 10.3390/ijerph192214921
PMID: 36429639

12 p, 1.2 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles