IAEA methodology for on-site end-to-end IMRT/VMAT audits : an international pilot study
Kazantsev, Pavel (International Atomic Energy Agency)
Lechner, Wolfgang (Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology)
Gershkevitsh, Eduard (North Estonia Medical Centre)
Clark, Catharine H. (Metrology for Medical Physics (MEMPHYS))
Venencia, Daniel (Instituto Privado de Radioterapia)
Van Dyk, Jacob (Western University)
Wesolowska, Paulina (International Atomic Energy Agency)
Hernandez Masgrau, Victor (Hospital Universitari Sant Joan de Reus (Tarragona))
Jornet, Nuria (Institut d'Investigació Biomèdica Sant Pau)
Tomsej, Milan (CHU Charleroi. Hopital Andre Vesale)
Bokulic, Tomislav (International Atomic Energy Agency)
Izewska, Joanna (International Atomic Energy Agency)
Universitat Autònoma de Barcelona

Data:	2020
Resum:	The IAEA has developed and tested an on-site, end-to-end IMRT/VMAT dosimetry audit methodology for head and neck cases using an anthropomorphic phantom. The audit methodology is described, and the results of the international pilot testing are presented. The audit utilizes a specially designed, commercially available anthropomorphic phantom capable of accommodating a small volume ion chamber (IC) in four locations (three in planning target volumes (PTVs) and one in an organ at risk (OAR)) and a Gafchromic film in a coronal plane for the absorbed dose to water and two-dimensional dose distribution measurements, respectively. The audit consists of a pre-visit and on-site phases. The pre-visit phase is carried out remotely and includes a treatment planning task and a set of computational exercises. The on-site phase aims at comparing the treatment planning system (TPS) calculations with measurements in the anthropomorphic phantom following an end-to-end approach. Two main aspects were tested in the pilot study: feasibility of the planning constraints and the accuracy of IC and film results in comparison with TPS calculations. Treatment plan quality was scored from 0 to 100. Results: Forty-two treatment plans were submitted by 14 institutions from 10 countries, with 79% of them having a plan quality score over 90. Seventeen sets of IC measurement results were collected, and the average measured to calculated dose ratio was 0. 988 ± 0. 016 for PTVs and 1. 020 ± 0. 029 for OAR. For 13 film measurement results, the average gamma passing rate was 94. 1% using criteria of 3%/3 mm, 20% threshold and global gamma. The audit methodology was proved to be feasible and ready to be adopted by national dosimetry audit networks for local implementation.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Publicat a:	Acta Oncologica, Vol. 59 Núm. 2 (january 2020) , p. 141-148, ISSN 1651-226X

DOI: 10.1080/0284186X.2019.1685128

9 p, 2.3 MB

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