Development of a prioritisation tool for the updating of clinical guideline questions : The UpPriority Tool protocol
Martínez García, Laura (Institut d'Investigació Biomèdica Sant Pau)
Pardo-Hernandez, Hector (Institut d'Investigació Biomèdica Sant Pau)
De Guzman, Ena Niño (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Superchi, Cecilia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Ballesteros Silva, Mónica Patricia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
McFarlane, Emma (National Institute for Health and Care Excellence)
Penman, Katrina (National Institute for Health and Care Excellence)
Posso, Margarita (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Roqué i Figuls, Marta (Institut d'Investigació Biomèdica Sant Pau)
Sanabria, Andrea Juliana (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Selva, A (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Vernooij, Robin W.M. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau)
Universitat Autònoma de Barcelona

Date:	2017
Abstract:	Due to a continuous emergence of new evidence, clinical guidelines (CGs) require regular surveillance of evidence to maintain their trustworthiness. The updating of CGs is resource intensive and time consuming; therefore, updating may include a prioritisation process to efficiently ensure recommendations remain up to date. The objective of our project is to develop a pragmatic tool to prioritise clinical questions for updating within a CG. To develop the tool, we will use the results and conclusions of a systematic review of methodological research on prioritisation processes for updating and will adopt a methodological approach we have successfully implemented in a previous experience. We will perform a multistep process including (1) generation of an initial version of the tool, (2) optimisation of the tool (feasibility test of the tool, semistructured interviews, Delphi consensus survey, external review by CG methodologists and users and pilot test of the tool) and (3) approval of the final version of the tool. At each step of the process, we will (1) calculate absolute frequencies and proportions (quantitative data), (2) use content analysis to summarise and draw conclusions (qualitative data) and (3) draft a final report, discuss results and refine the previous versions of the tool. Finally, we will calculate intraclass coefficients with 95% CIs for each item and overall as indicators of agreement among reviewers. We have obtained a waiver of approval from the Clinical Research Ethics Committee at the Hospital de la Santa Creu i Sant Pau (Barcelona). The results of the study will be published in peer-reviewed journal and communicated to interested stakeholders. The tool could support the standardisation of prioritisation processes for updating CGs and therefore have important implications for a more efficient use of resources in the CG field.
Grants:	Ministerio de Economía y Competitividad PI15/00325 Ministerio de Economía y Competitividad JR15/00004 Ministerio de Economía y Competitividad PI15/00034
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Clinical guidelines ; Evidence-based medicine ; Methodology ; Prioritisation ; Updating
Published in:	BMJ open, Vol. 7 Núm. 8 (january 2017) , p. e017226, ISSN 2044-6055

DOI: 10.1136/bmjopen-2017-017226
PMID: 28775194

8 p, 322.7 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles