Experience in Spain with the first patients in home hemodialysis treated with low-flow dialysate monitors Experiencia en España con los primeros pacientes en hemodiálisis domiciliaria tratados con monitores de bajo flujo de líquido de diálisis
Slon Roblero, Maria Fernanda (Complejo Hospitalario Navarra)
Bajo Rubio, Maria Auxiliadora (Hospital Universitario La Paz (Madrid))
González-Moya, Mercedes (Hospital Universitari Dr. Peset)
Calviño Varela, Jesús (Hospital Universitario Lucus Augusti (Lugo))
Pérez Alba, Alejandro (Consorci Hospitalari Provincial de Castelló)
Villaro Gumpert, Juan (Hospital General Universitario de Valencia)
Cigarrán, Secundino (Hospital da Costa)
Vidau, Pedro (Hospital Universitario Central de Asturias)
García Marcos, Sergio (Hospital de Poniente)
Abáigar Luquin, Pedro (Hospital Universitario de Burgos)
Coll, Elisabet (Institut d'Investigació Biomèdica Sant Pau)
Gascón Mariño, Antonio (Hospital Obispo Polanco)
Espigares, Maria José (Hospital Virgen de las Nieves (Granada, Andalusia))
Molina, Mariola D. (Universidad de Alicante)
Molina, Pablo (Universitat de València)
Universitat Autònoma de Barcelona

Date:	2022
Abstract:	Home hemodialysis (HHD) with low-flow dialysate devices has gained popularity in recent years due to its simple design, portability, and ability to provide greater freedom of movement for our patients. However, there are doubts about the adequacy that this technology offers, since it uses monitors with low-flow bath and lactate. The aim of this study was to demonstrate the clinical benefits of low-flow HHD with the NxStage System One® recently introduced in Spain. We present the results of an observational, retrospective cohort study that included the first patients who started short daily HHD with this device in 12 Spanish centers. We analyzed the evolution of 86 patients at 0, 6 and 12 months, including data related to prescription, and evolution of biochemical parameters related to dialysis dose, anemia, mineral-bone metabolism; evolution of residual renal function, medication usage, and causes of withdrawal during the followup. We were able to demonstrate that this NxStage System One® monitor, in patients with HHD, have provided an adequate dialysis dose, with optimal ultrafiltration rate, with improvement of main biochemical markers of dialysis adequacy. The usage of this technique was associated to a decrease of antihypertensive drugs, phosphate binders and erythropoietin agents, with very good results both patient and technique survival. The simplicity of the technique, together with its good clinical outcomes, should facilitate the growth and utilization of HHD, both in incident and prevalent patients.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Castellà
Document:	Article ; recerca ; Versió publicada
Subject:	Adecuación ; Adequacy ; Dializado de bajo flujo ; Hemodiálisis domiciliaria ; Hemodiálisis intensiva ; Home hemodialysis ; Intensive hemodialysis ; Lactate ; Lactato ; Low flow dialysate
Published in:	Nefrología (Madrid), Vol. 42 Núm. 4 (enero 2022) , p. 460-470, ISSN 1989-2284

DOI: 10.1016/j.nefro.2021.07.001
PMID: 34393002

11 p, 1004.9 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles