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8 p, 973.9 KB |
PCSK9 plasma concentration is associated with epicardial adipose tissue volume and metabolic control in patients with type 1 diabetes
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Sardà, Helena (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Colom, Cristina (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Benitez, Sonia (Institut de Recerca Sant Pau) ;
Carreras, Gemma (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Amigó, Judit (Hospital Universitari Vall d'Hebron) ;
Miñambres, Inka (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Viladés Medel, David (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Blanco Vaca, Francisco (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sanchez-Quesada, Jose Luis (Institut de Recerca Sant Pau) ;
Pérez Pérez, Antonio (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
Patients with type 1 diabetes (T1D) have a greater risk of cardiovascular disease. Proconvertase subtilisin-kexin 9 (PCSK9) is involved in the atherosclerosis process. This study aimed to determine the relationship between PCSK9 levels and epicardial adipose tissue (EAT) volume and cardiometabolic variables in patients with T1D. [...]
2024 -  10.1038/s41598-024-57708-5
Scientific reports, Vol. 14 (march 2024)
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19 p, 2.0 MB |
Lyophilized maqui (Aristotelia chilensis) berry induces browning in the subcutaneous white adipose tissue and ameliorates the insulin resistance in high fat diet-induced obese mice
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Sandoval, Viviana (Universitat de Barcelona. Institut de Recerca en Nutrició i Seguretat Alimentària) ;
Femenias, Antoni (Universitat de Lleida. Departament de Tecnologia d'Aliments) ;
Martínez-Garza, Úrsula (Universitat de Barcelona. Institut de Recerca en Nutrició i Seguretat Alimentària) ;
Sanz-Lamora, Hèctor (Universitat de Barcelona. Institut de Recerca en Nutrició i Seguretat Alimentària) ;
Castagnini, Juan Manuel (Universidad Nacional de Entre Ríos. Facultad de Ciencias de la Alimentación) ;
Quifer-Rada, Paola (Institut d'Investigació Biomèdica Sant Pau) ;
Lamuela-Raventós, Rosa M (CIBER Physiopathology of Obesity and Nutrition (CIBER-OBN). Instituto de Salud Carlos III) ;
Marrero, Pedro F. (Universitat de Barcelona. Institut de Biomedicina) ;
Haro, Diego (Universitat de Barcelona. Institut de Biomedicina) ;
Relat, Joana (CIBER Physiopathology of Obesity and Nutrition (CIBER-OBN). Instituto de Salud Carlos III)
Maqui (Aristotelia Chilensis) berry features a unique profile of anthocyanidins that includes high amounts of delphinidin-3-O-sambubioside-5-O-glucoside and delphinidin-3-O-sambubioside and has shown positive effects on fasting glucose and insulin levels in humans and murine models of type 2 diabetes and obesity. [...]
2019 - 10.3390/antiox8090360
Antioxidants, Vol. 8 Núm. 9 (september 2019) , p. 360
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9 p, 8.0 MB |
Overexpressing high levels of human vaspin limits high fat diet-induced obesity and enhances energy expenditure in a transgenic mouse
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Rapöhn, Inka (University of Leipzig) ;
Elias Puigdomenech, Ivet (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Weiner, Juliane (University of Leipzig Medical Center) ;
Pujol, Anna (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Kehr, Stephanie (Leipzig University) ;
Chadt, Alexandra (German Center for Diabetes Research) ;
Al-Hasani, Hadi (German Center for Diabetes Research) ;
Burkhardt, Ralph (University Hospital Regensburg) ;
Klöting, Nora (University of Leipzig) ;
Stumvoll, Michael (University of Leipzig) ;
Bosch i Tubert, Fàtima (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ;
Kovacs, Peter (German Center for Diabetes Research) ;
Heiker, John T. (University of Leipzig Medical Center) ;
Breitfeld, Jana (Leipzig Medical Center)
Adipose tissue inflammation and insulin resistance are hallmarks in the development of metabolic diseases resulting from overweight and obesity, such as type 2 diabetes and non-alcoholic fatty liver disease. [...]
2023 - 10.3389/fendo.2023.1146454
Frontiers in Endocrinology, Vol. 14 (April 2023) , art. 1146454
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13 p, 3.5 MB |
Electrophysiological effects of adipose graft transposition procedure (AGTP) on the post-myocardial infarction scar : A multimodal characterization of arrhythmogenic substrate
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Adeliño, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez-Falguera, Daina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Curiel, Carolina (Boston Scientific Department. Barcelona Delegation) ;
Teis, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Marsal, Roger (Boston Scientific Department. Barcelona Delegation) ;
Rodríguez-Leor, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prat-Vidal, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Fadeuilhe, Edgar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Aranyó, Júlia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Revuelta-López, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sarrias, Axel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bazán, Víctor (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Andrés-Cordón, Joan Francesc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Villuendas-Sabaté, Roger (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bisbal, Felipe (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
To assess the arrhythmic safety profile of the adipose graft transposition procedure (AGTP) and its electrophysiological effects on post-myocardial infarction (MI) scar. Myocardial repair is a promising treatment for patients with MI. [...]
2022 - 10.3389/fcvm.2022.983001
Frontiers in Cardiovascular Medicine, Vol. 9 (september 2022)
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16 p, 3.3 MB |
Smoking Suppresses the Therapeutic Potential of Adipose Stem Cells in Crohn's Disease Patients through Epigenetic Changes
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Boronat-Toscano, Albert (Hospital Universitari Joan XXIII de Tarragona) ;
Vañó, Irene (Institut d'Investigació Sanitària Pere Virgili) ;
Monfort-Ferré, Diandra (Hospital Universitari Joan XXIII de Tarragona) ;
Menacho, Margarita (Hospital Universitari Joan XXIII de Tarragona) ;
Valldosera, Gemma (Hospital Universitari Joan XXIII de Tarragona) ;
Caro, Aleidis (Hospital Universitari Joan XXIII de Tarragona) ;
Espina, Beatriz (Hospital Universitari Joan XXIII de Tarragona) ;
Mañas, Maria José (Hospital Sant Pau i Santa Tecla (Tarragona)) ;
Marti-Gallostra, Marc (Hospital Universitari Vall d'Hebron) ;
Espin-Basany, Eloy (Hospital Universitari Vall d'Hebron) ;
Saera-Vila, Alfonso (Sequentia Biotech) ;
Serena, Carolina (Institut d'Investigació Sanitària Pere Virgili) ;
Universitat Autònoma de Barcelona
Patients with Crohn's disease (CD) who smoke are known to have a worse prognosis than never-smokers and a higher risk for post-surgical recurrence, whereas patients who quit smoking after surgery have significantly lower post-operative recurrence. [...]
2023 - 10.3390/cells12071021
Cells, Vol. 12 (march 2023)
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11 p, 2.0 MB |
Adipose tissue aging partially accounts for fat alterations in HIV lipodystrophy
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Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Giralt, Marta (Institut de Recerca Sant Joan de Déu) ;
Gavaldà i Navarro, Aleix (Institut de Recerca Sant Joan de Déu) ;
Blasco-Roset, Albert (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Delgado-Anglés, Alejandro (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Gallego-Escuredo, José Miguel (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Gutierrez, Mª del Mar (Institut d'Investigació Biomèdica Sant Pau) ;
Mateo, María Gracia (Institut d'Investigació Biomèdica Sant Pau) ;
Cereijo, Rubén (Institut d'Investigació Biomèdica Sant Pau) ;
Domingo, Joan Carles (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ;
Villarroya, Francesc (Institut de Recerca Sant Joan de Déu) ;
Villarroya, Joan (Institut de Recerca Sant Joan de Déu)
Lipodystrophy is a major disturbance in people living with HIV-1 (PLWH). Several systemic alterations in PLWH are reminiscent of those that occur in ageing. It is unknown whether the lipodystrophy in PLWH is the consequence of accelerated ageing in adipose tissue. [...]
2022 - 10.1080/21623945.2022.2042962
Adipocyte, Vol. 11 Núm. 1 (2022) , p. 143-152
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21 p, 33.2 MB |
Microsomal prostaglandin E synthase-1 is involved in the metabolic and cardiovascular alterations associated with obesity
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Ballesteros-Martínez, Constanza (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ;
Rodrigues-Díez, Raquel (CIBER de Enfermedades Cardiovasculares. ISCIII) ;
Beltrán, Luis M. (Instituto de Biomedicina de Sevilla) ;
Moreno-Carriles, Rosa (Hospital Universitario de la Princesa (Madrid)) ;
Martínez-Martínez, Ernesto (Universidad Complutense de Madrid. Departamento de Fisiología) ;
González-Amor, María (CIBER de Enfermedades Cardiovasculares. ISCIII) ;
Martínez-González, José (Institut d'Investigació Biomèdica Sant Pau) ;
Rodríguez, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Cachofeiro, Victoria (Universidad Complutense de Madrid. Departamento de Fisiología) ;
Salaices, Mercedes (CIBER de Enfermedades Cardiovasculares. ISCIII) ;
Briones, Ana M. (CIBER de Enfermedades Cardiovasculares. ISCIII)
Background and Purpose: Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible isomerase responsible for prostaglandin E production in inflammatory conditions. We evaluated the role of mPGES-1 in the development and the metabolic and cardiovascular alterations of obesity. [...]
2022 - 10.1111/bph.15776
British Journal of Pharmacology, Vol. 179 Núm. 11 (june 2022) , p. 2733-2753
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13 p, 1.4 MB |
Effects of a Calorie-Restricted Cafeteria Diet and Oleuropein Supplementation on Adiposity and mRNA Expression of Energy Balance Related Genes in Obese Male Rats
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Subias-Gusils, Alex (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Álvarez-Monell, Adam (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Boqué, Noemí (Eurecat, Centre Tecnològic de Catalunya, Biotechnology Area and Technological Unit of Nutrition and Health) ;
Caimari, Antoni (Eurecat, Centre Tecnològic de Catalunya, Biotechnology Area and Technological Unit of Nutrition and Health) ;
Mariné-Casadó, Roger (Eurecat, Centre Tecnològic de Catalunya, Biotechnology Area and Technological Unit of Nutrition and Health) ;
Escorihuela, Rosa M (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Solanas i Garcia, Montserrat (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Supplementation with natural bioactive compounds has been proposed to be a complementary tool to the calorie-restricted diets and physical exercise programs used to tackle human overweight, obesity and Metabolic syndrome. [...]
2023 - 10.3390/metabo13020147
Metabolites, Vol. 13 (january 2023)
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13 p, 1.2 MB |
Effect of polyphenols intake on obesity-induced maternal programming
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Fortunato, Isabela Monique (Post Graduate Program in Health Science. Universidade São Francisco (USF)) ;
Dos Santos, Tanila Wood (Post Graduate Program in Health Science. Universidade São Francisco (USF)) ;
Ferraz, Lucio Fábio Caldas (Post Graduate Program in Health Science. Universidade São Francisco (USF)) ;
Santos, Juliana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ribeiro, Marcelo Lima (Post Graduate Program in Health Science. Universidade São Francisco (USF))
Excess caloric intake and body fat accumulation lead to obesity, a complex chronic disease that represents a significant public health problem due to the health-related risk factors. There is growing evidence showing that maternal obesity can program the offspring, which influences neonatal phenotype and predispose offspring to metabolic disorders such as obesity. [...]
2021 - 10.3390/nu13072390
Nutrients, Vol. 13 Núm. 7 (july 2021) , p. 2390
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