2026-03-18
15:49 |
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9 p, 920.8 KB |
Isolated IgG elevation in patients with persistently normal transaminases does not affect the outcome of autoimmune hepatitis
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Díaz-González, Álvaro (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Schregel, Ida (University Medical Center Hamburg-Eppendorf) ;
Carballo, Lorena (Hospital Universitario Central de Asturias) ;
Álvarez-Navascués, Carmen (Hospital Universitario Central de Asturias) ;
Frisancho-Morales, Enrique (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Miquel Planas, Mireia (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Retortillo, Montserrat García (Parc de Salut MAR de Barcelona) ;
Gómez, Judith (Hospital Universitario de Burgos) ;
Horta Sangenís, Diana (Hospital Universitari MútuaTerrassa) ;
Mateos Muñoz, Beatriz (Hospital Universitario Ramón y Cajal (Madrid)) ;
Engel, Bastian (Hannover Medical School) ;
Volmer, Felix (Hannover Medical School) ;
Barrio, María del (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Rodríguez-Tajes, Sergio (Universitat de Barcelona) ;
Olivas, Ignasi (Universitat de Barcelona) ;
Hartl, Johannes (University Medical Center Hamburg-Eppendorf) ;
González, Carla Amaral (Hospital Universitario de Canarias (La Laguna)) ;
Hernandez-Guerra, Manuel (Hospital Universitario de Canarias (La Laguna)) ;
Castello, Inmaculada (Hospital General Universitario de Valencia) ;
Pérez-Medrano, Indhira (Complejo Hospitalario Universitario de Pontevedra) ;
González Santiago, Jesús M. (Complejo Asistencial Universitario de Salamanca) ;
Arencibía, Ana (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Gómez, Alberto (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Rodríguez-Perálvarez, Manuel (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Crespo García, Javier (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Sala, Margarita (Hospital Universitari de Girona Doctor Josep Trueta) ;
Salcedo, Magdalena (Hospital General Universitario Gregorio Marañón) ;
Barreira-Diaz, Ana (Hospital Universitari Vall d'Hebron) ;
Riveiro Barciela, Mar (Hospital Universitari Vall d'Hebron) ;
Taubert, Richard (Hannover Medical School) ;
Schramm, Christoph (University Medical Center Hamburg-Eppendorf) ;
Londoño, María-Carlota (Universitat de Barcelona)
The goal of treatment for autoimmune hepatitis is to achieve a complete biochemical response, defined as normalization of transaminases and immunoglobulin G (IgG) levels. Recent data suggest that IgG normalization does not significantly affect survival. [...]
2025 -  10.1016/j.jhepr.2025.101562
JHEP Reports, Vol. 7, Num. 11 (August 2025) , art. 101562
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2026-03-18
20:12 |
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23 p, 1.1 MB |
Therapeutic Alliances for Optimizing the Management of Patients with Prostate Cancer : SOGUG Multidisciplinary Expert Panel Recommendations
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González-del-Alba, Aránzazu (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Martínez Ballesteros, Claudio (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Arranz, José Ángel (Hospital General Universitario Gregorio Marañón) ;
Gallardo Díaz, Enrique (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Gironés Sarrió, Regina (Hospital Universitari i Politècnic La Fe (València)) ;
Lopez Campos, Fernando (Hospital Universitario Ramón y Cajal (Madrid)) ;
Muñoz-Rodríguez, Jesús (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Méndez-Vidal, María José (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Gómez de Iturriaga, Alfonso (Hospital Universitario de Cruces (Barakaldo, País Basc))
Prostate cancer (PCa) is a clinically relevant disease because it is one of the most common cancer types in men and one of the leading causes of cancer-related death. Prostate cancer is a heterogeneous disease, although most cases of PCa are slow and often indolent, with a low propensity to progress. [...]
2025 - 10.3390/cancers17193208
Cancers, Vol. 17, Num. 19 (October 2025) , art. 3208
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2026-03-23
16:12 |
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12 p, 1.1 MB |
Efficacy of inhaled nebulised unfractionated heparin to prevent intubation or death in hospitalised patients with COVID-19 : an investigator-initiated international meta-trial of randomised clinical studies
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van Haren, Frank M.P. (Australian National University) ;
Neto, Ary Serpa (St George Hospital) ;
Schultz, Marcus J. (Mahidol University (Tailàndia)) ;
Laffey, John (University of Galway (Escòcia)) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Dixon, Barry (St Vincent's Hospital (Sydney)) ;
Vilaseca, Alicia B (San Camilo Clinic) ;
Barbera, Ruben A (San Camilo Clinic) ;
Ismail, Tarek I (Helwan University) ;
Mahrous, Rabab S (Alexandria University (Egipte)) ;
Badr, Mohamed (Helwan University) ;
DeNucci, Gilberto (Universidade de São Paulo) ;
Sverdloff, Carlos (University of Campinas (Brasil)) ;
Camprubí-Rimblas, Marta (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Cosgrave, David W (University of Galway (Escòcia)) ;
McNicholas, Bairbre (University of Galway (Escòcia)) ;
Cody, Catriona (Connolly Memorial Hospital Blanchardstown) ;
Curley, Gerard (Beaumont Hospital (Dublín, Irlanda)) ;
Smoot, Thomas L. (Frederick Memorial Hospital) ;
Staas, Sabrina (Frederick Memorial Hospital) ;
Sann, Khine (Frederick Memorial Hospital) ;
Sas, Caitlin (Frederick Memorial Hospital) ;
Belani, Anusha (Frederick Memorial Hospital) ;
Hillman, Christopher (Frederick Memorial Hospital) ;
Manggala, Sidharta K. (RSUP Dr Cipto Mangunkusumo) ;
Dita Aditianingsih (RSUP Dr Cipto Mangunkusumo) ;
Sugiarto, Adhrie (RSUP Dr Cipto Mangunkusumo) ;
Yulianti, Mira (RSUP Dr Cipto Mangunkusumo) ;
Herikurniawan, Herikurniawan (RSUP Dr Cipto Mangunkusumo) ;
Sinto, Robert (RSUP Dr Cipto Mangunkusumo) ;
Auerkari, Aino N. (RS Universitas Indonesia) ;
Permana, Septian Adi (RSUD Dr Moewardi) ;
Woodcock, Ashley (University of Manchester) ;
Carroll, Mary (University of Southampton) ;
Wilkinson, Tom (University of Southampton) ;
Singh, Dave (University of Manchester) ;
Shute, Janis (University of Portsmouth) ;
Carroll, Miles (University of Oxford) ;
Page, Clive (King's College London)
Inhaled nebulised unfractionated heparin (UFH) has a strong rationale as a treatment for severe respiratory infections, including COVID-19, due to its antiviral, anti-inflammatory, and anti-coagulant properties, which may prevent viral entry, lung injury progression, and pulmonary thrombosis. [...]
2025 - 10.1016/j.eclinm.2025.103339
EClinicalMedicine, Vol. 88 (September 2025) , art. 103339
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2026-03-20
16:12 |
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10 p, 1.1 MB |
Mammographic density and breast cancer pathological subtypes by menopausal status and body mass index
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Fernández-Morata, Julia (Instituto Mixto de Investigación Escuela Nacional de Sanidad UNED-IMIENS) ;
Pollán, Marina (Instituto de Salud Carlos III) ;
Fernández de Larrea-Baza-Baz, Nerea (Instituto de Salud Carlos III) ;
Pachón-Olmos, Vanessa (Hospital Universitario La Paz (Madrid)) ;
García-Pérez, Javier (Instituto de Salud Carlos III) ;
Castelló, Adela (Instituto de Salud Carlos III) ;
Sierra, María Ángeles (Instituto de Salud Carlos III) ;
Lucas, Pilar (Instituto de Salud Carlos III) ;
Llobet, Rafael (Universitat Politècnica de València) ;
Stradella, Agostina (Institut Català d'Oncologia) ;
Cantos, Blanca (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Ramon y Cajal, Teresa (Institut de Recerca Sant Pau) ;
Santisteban, Marta (Clínica Universidad de Navarra) ;
Seguí, Miguel Ángel (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Santaballa Bertrán, Ana (Hospital Universitari i Politècnic La Fe (València)) ;
Granja, Mónica (Hospital Universitario Clínico San Carlos (Madrid)) ;
Camps-Herrero, Julia (Hospital Universitari de la Ribera (València)) ;
Recalde, Sabela (Institut Català d'Oncologia) ;
Nuñez-García, Beatriz (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Calvo Verges, Nuria (Institut de Recerca Sant Pau) ;
Pérez-Gómez, Beatriz (Instituto de Salud Carlos III) ;
Pastor-Barriuso, Roberto (Instituto de Salud Carlos III) ;
Lope, Virginia (Instituto de Salud Carlos III) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Mammographic density (MD) is an established biomarker of breast cancer (BC) risk. However, its relationship to BC pathological subtypes remains unclear. This study aimed to investigate this association and assess whether it differs by body mass index (BMI) and menopausal status. [...]
2025 - 10.1186/s13058-025-02142-2
Breast cancer research, Vol. 27, Num. 1 (October 2025) , art. 187
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2026-03-18
13:18 |
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9 p, 1.5 MB |
A predictive model for early intubation in patients with COVID-19-induced acute hypoxemic respiratory failure under awake prone position
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Morales-Quinteros, Luis (Vall d'Hebron Institut de Recerca (VHIR)) ;
Fuentes, Nora Angélica (Universidad Nacional de Mar del Plata) ;
Muriel, Alfonso (Hospital Universitario Ramón y Cajal (Madrid)) ;
Olmos, Matías (Universidad Nacional de Mar del Plata) ;
Busico, Marina (Clínica Olivos SMG) ;
Vitali, Alejandra (Sanatorio de la Trinidad Palermo) ;
Gallardo, Adrián (Universidad de Morón) ;
Plata-Menchaca, Erika P. (Hospital Universitari Vall d'Hebron) ;
Ferrer, Ricard (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Artigas Raventós, Antoni (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Esperatti, Mariano (Universidad Nacional de Mar del Plata)
Awake prone positioning (APP) reduces the risk of endotracheal intubation and mortality in COVID-19-related acute respiratory failure (ARF) receiving high-flow nasal oxygen (HFNO). However, a significant proportion of patients undergoing APP are ultimately intubated, and mortality in this subgroup remains high. [...]
2025 - 10.1186/s13613-025-01602-4
Annals of Intensive Care, Vol. 15, Num. 1 (November 2025) , art. 188
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2026-03-17
17:04 |
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11 p, 822.4 KB |
Multicentre, prospective, randomized controlled non-inferiority trial of bladder catheter management in short-duration, minimally invasive colon surgery (The Vesicalcath I-Study)
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Serra-Aracil, Xavier (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Hidalgo, Jose (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Perucho, Nuria Llorach (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Montesinos, Cristina Soto (Fundació Althaia (Manresa)) ;
Diaz, Carlos Gómez (Fundació Althaia (Manresa)) ;
Figueras, Regina Vives (Fundació Althaia (Manresa)) ;
Rivilla, Salvadora Delgado (Hospital Universitari MútuaTerrassa) ;
Romero Marcos, Juan Manuel (Hospital Universitari MútuaTerrassa) ;
Gomez, Carlota Cuenca (Hospital Universitari MútuaTerrassa) ;
Ferreres-Serafini, Joan (Hospital Universitari Joan XXIII de Tarragona) ;
Romaguera, Vincent Primo (Hospital Universitari i Politècnic La Fe (València)) ;
Galvez, Ana (Hospital Universitari de Bellvitge) ;
Caro, Aleidis (Hospital Universitari Joan XXIII de Tarragona)
Urinary catheterizationis a routine practice during major surgery to aid fluid resuscitation and monitor hemodynamic stability. However, the optimal duration for catheter retention remains controversial due to associated complications like acute urinary retention (AUR) and urinary tract infections (UTIs). [...]
2025 - 10.1097/JS9.0000000000002962
International journal of surgery, Vol. 111, Num. 11 (November 2025) , p. 8088-8098
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2026-03-17
17:01 |
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12 p, 478.1 KB |
Cross-cultural adaptation and psychometric validation of the Spanish version of the SBAR-LA rubric for structured communication in nursing simulation
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Carballedo-Pulido, Jaime (Universitat de Vic-Universitat Central de Catalunya, Vic, Spain) ;
Farrés-Tarafa, Mariona (Universitat de Barcelona) ;
Roldán Merino, Juan Francisco (Universitat de Vic-Universitat Central de Catalunya, Vic, Spain) ;
Berenguer-Poblet, Marta (Universitat Rovira i Virgili) ;
Girabent-Farrés, Montserrat (Universitat de Vic-Universitat Central de Catalunya, Vic, Spain) ;
Otero-Arús, Carla (Universitat de Vic-Universitat Central de Catalunya, Vic, Spain) ;
Santos-Ruiz, Susana (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona.
Departament d'Infermeria
Although the SBAR framework is widely used in clinical and educational settings, there is a lack of validated Spanish-language tools that objectively assess its use by students in simulation. The adaptation and validation of the SBAR-LA rubric address this gap and provide a resource for training and evaluating structured communication. [...]
2025 - 10.1371/journal.pone.0337533
PloS one, Vol. 20, Num. 11 (November 2025) , art. e0337533
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2026-03-17
16:55 |
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9 p, 1000.0 KB |
The Absence of International Standardized Quality Criteria in Doctorate Programs in Surgery : A Survey Study
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Llorach-Perucho, Núria (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pera Román, Manuel (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Espin-Basany, Eloy (Hospital Universitari Vall d'Hebron) ;
Julián Ibáñez, Joan Francesc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Morote Robles, Juan (Hospital Universitari Vall d'Hebron) ;
Amat-Lefort, Natalia (Leiden University) ;
Serra-Gómez, Álvaro (Leiden University) ;
Grande, L. (Hospital del Mar (Barcelona, Catalunya)) ;
Navarro Soto, Salvador (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Serra-Aracil, Xavier (Universitat Autònoma de Barcelona. Departament de Cirurgia)
A doctorate degree in surgery is awarded by universities in recognition of high-standard academic research. This study explores the global heterogeneity of PhD programs in surgery and evaluates them using a standardized rating scale. [...]
2025 - 10.1177/23821205251389679
Journal of Medical Education and Curricular Development, Vol. 12 (November 2025) , art. 23821205251389679
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2026-03-17
16:41 |
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9 p, 904.2 KB |
PD-L1 and the risk of bacterial infection in patients with chronic liver diseases : An international multicohort study
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Juanola, Adrià (Hospital Clínic i Provincial de Barcelona) ;
Mezzano, Gabriel (Universidad de los Andes (Xile)) ;
Pose, Elisa (Hospital Clínic i Provincial de Barcelona) ;
Moreta, Maria J. (Hospital Clínic i Provincial de Barcelona) ;
Incicco, Simone (University and Hospital of Padova) ;
Gagliardi, Roberta (University and Hospital of Padova) ;
Johansen, Stine (University of Southern Denmark) ;
Torp, Nikolaj (University of Southern Denmark) ;
Israelsen, Mads (University of Southern Denmark) ;
Jiménez-Esquivel, Natalia (Hospital Clínic i Provincial de Barcelona) ;
Castillo-Iturra, Joaquin (Hospital Clínic i Provincial de Barcelona) ;
Ribera Salas, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Gratacós-Ginès, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Soria, Anna (Hospital Clínic i Provincial de Barcelona) ;
Cárdenas, Andrés (Hospital Clínic i Provincial de Barcelona) ;
Pérez-Guasch, Martina (Hospital Clínic i Provincial de Barcelona) ;
Cervera, Marta (Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain) ;
Nadal, Ruth (Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain) ;
Herms, Queralt (Hospital Clínic i Provincial de Barcelona) ;
Tonon, Marta (University and Hospital of Padova) ;
Hansen, Torben (University of Copenhagen) ;
Stankevic, Evelina (University of Copenhagen) ;
Huang, Yun (University of Copenhagen) ;
Vargas Blasco, Víctor (Hospital Universitari Vall d'Hebron) ;
Zaccherini, Giacomo (IRCCS Azienda Ospedaliero-Universitaria di Bologna) ;
Alessandria, Carlo (University of Turin) ;
Uschner, Frank E. (University Hospital of Münster (Alemanya)) ;
Beuers, Ulrich (Universiteit van Amsterdam) ;
Francoz, Claire (Centre de Recherche sur l'Inflammation, France) ;
Mookerjee, Rajeshwar P. (Aarhus University) ;
Laleman, Wim (UZ Leuven) ;
Solé Marcé, Cristina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Bañares, Rafael (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Cuyàs, Berta (Institut de Recerca Sant Pau) ;
Ariza, Xavi (Hospital de Sant Joan Despí Moisès Broggi) ;
Coll, Mar (Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEREHD), Madrid, Spain) ;
Graupera, Isabel (Hospital Clínic i Provincial de Barcelona) ;
Fabrellas, Núria (Universitat de Barcelona) ;
Morales Ruiz, Manuel (Hospital Clínic i Provincial de Barcelona) ;
Thiele, Maja (University of Southern Denmark) ;
Krag, Aleksander (University of Southern Denmark) ;
Angeli, Paolo (University and Hospital of Padova) ;
Piano, Salvatore (University and Hospital of Padova) ;
Solà, Elsa (Stanford University School of Medicine) ;
Ginès, Pere (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Impaired phagocytic capacity due to activation of the PD-1/PD-L1 pathway has been implicated in the development of bacterial infections in patients with cirrhosis. Soluble PD-L1 (sPD-L1) is easily measurable in plasma and has been proposed as a biomarker of sepsis. [...]
2025 - 10.1016/j.jhepr.2025.101597
JHEP Reports, Vol. 7 (September 2025) , art. 101597
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2026-03-16
16:51 |
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14 p, 1.1 MB |
Personalized mechanical ventilation guided by ultrasound in patients with acute respiratory distress syndrome (PEGASUS) : study protocol for an international randomized clinical trial
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Sinnige, Jante S. (Universiteit van Amsterdam) ;
Smit, Marry R. (Universiteit van Amsterdam) ;
Ghose, Aniruddha (Chattogram Medical Centre) ;
de Grooth, Harm-Jan (Vrije Universiteit) ;
Itenov, Theis Skovsgaard (University of Copenhagen) ;
Ischaki, Eleni (University of Athens Medical School) ;
Laffey, John (University of Galway) ;
Paulus, Frederique (Universiteit van Amsterdam) ;
Póvoa, Pedro (University of Lisbon) ;
Pierrakos, Charalampos (Université Libre de Bruxelles) ;
Pisani, Luigi (Università degli Studi di Bari Aldo Moro) ;
Roca Gas, Oriol (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Schultz, Marcus J. (University of Oxford) ;
Szuldrzynski, Konstanty (National Institute of Medicine of the Ministry of Interior and Administration) ;
Tuinman, Pieter R. (Vrije Universiteit Amsterdam) ;
Zimatore, Claudio (Università degli Studi di Bari Aldo Moro) ;
Bos, Lieuwe D. (Universiteit van Amsterdam) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
Acute respiratory distress syndrome (ARDS) is a frequent cause of hypoxemic respiratory failure with a mortality rate of approximately 30%. Identifying ARDS subphenotypes based on "focal" or "non-focal" lung morphology has the potential to better target mechanical ventilation strategies of individual patients. [...]
2024 - 10.1186/s13063-024-08140-7
Trials, Vol. 25 (May 2024) , art. 308
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