Web of Science: 277 cites, Scopus: 281 cites, Google Scholar: cites
Validation of the "World Health Organization Disability Assessment Schedule, WHODAS-2" in patients with chronic diseases
Garin, Olatz (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya))
Ayuso-Mateos, Jose Luis (Hospital Universitario de la Princesa (Madrid))
Almansa, Josué (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya))
Nieto, Marta (Hospital Universitario de la Princesa (Madrid))
Chatterji, Somnath (Organización Mundial de la Salud)
Vilagut, Gemma (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya))
Alonso Caballero, Jordi (Institut Municipal d'Investigació Mèdica (Barcelona, Catalunya))
Cieza, Alarcos (Ludwig-Maximilians-University (Munic, Alemanya))
Svetskova, Olga (Charles University (Praga, República Txeca))
Burger, Helena (Institute for Rehabilitation (Ljubljana, Eslovènia))
Racca, Vittorio (Fondazione Don Carlo Gnocchi-Onlus (Milà, Itàlia))
Francescutti, Carlo (Agenzia Regionale Sanità (Pordenone, Itàlia))
Vieta, Eduard (Hospital Clínic i Provincial de Barcelona)
Kostanjsek, Nenad (Organización Mundial de la Salud)
Raggi, Alberto (IRCCS Neurological Institute Carlo Besta (Milà, Itàlia))
Leonardi, Matilde (IRCCS Neurological Institute Carlo Besta (Milà, Itàlia))
Ferrer Forés, Maria Montserrat (Universitat Autònoma de Barcelona. Departament de Pediatria, d'Obstetrícia i Ginecologia i de Medicina Preventiva)
MHADIE Consortium

Data: 2010
Resum: Background: The WHODAS-2 is a disability assessment instrument based on the conceptual framework of the International Classification of Functioning, Disability, and Health (ICF). It provides a global measure of disability and 7 domain-specific scores. The aim of this study was to assess WHODAS-2 conceptual model and metric properties in a set of chronic and prevalent clinical conditions accounting for a wide scope of disability in Europe. Methods: 1,119 patients with one of 13 chronic conditions were recruited in 7 European centres. Participants were clinically evaluated and administered the WHODAS-2 and the SF-36 at baseline, 6 weeks and 3 months of follow-up. The latent structure was explored and confirmed by factor analysis (FA). Reliability was assessed in terms of internal consistency (Cronbach's alpha) and reproducibility (intra-class correlation coefficients, ICC). Construct validity was evaluated by correlating the WHODAS-2 and SF-36 domains, and comparing known groups based on the clinical-severity and work status. Effect size (ES) coefficient was used to assess responsiveness. To assess reproducibility and responsiveness, subsamples of stable (at 6 weeks) and improved (after 3 moths) patients were defined, respectively, according to changes in their clinical-severity. Results: The satisfactory FA goodness of fit indexes confirmed a second order factor structure with 7 dimensions, and a global score for the WHODAS-2. Cronbach's alpha ranged from 0. 77 (self care) to 0. 98 (life activities: work or school), and the ICC was lower, but achieved the recommended standard of 0. 7 for four domains. Correlations between global WHODAS-2 score and the different domains of the SF-36 ranged from -0. 29 to -0. 65. Most of the WHODAS-2 scores showed statistically significant differences among clinical-severity groups for all pathologies, and between working patients and those not working due to ill health (p < 0. 001). Among the subsample of patients who had improved, responsiveness coefficients were small to moderate (ES = 0. 3-0. 7), but higher than those of the SF-36. Conclusions: The latent structure originally designed by WHODAS-2 developers has been confirmed for the first time, and it has shown good metric properties in clinic and rehabilitation samples. Therefore, considerable support is provided to the WHODAS-2 utilization as an international instrument to measure disability based on the ICF model.
Drets: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Llengua: Anglès
Document: Article ; recerca ; Versió publicada
Publicat a: Health and quality of life outcomes, Vol. 8, N. 51 (May 2010) , p. 1-15, ISSN 1477-7525

DOI: 10.1186/1477-7525-8-51
PMID: 20482853

15 p, 1.0 MB

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